Arterial Stiffness, Wave Reflections and Renal Failure

This study is currently recruiting participants.

Verified by Klinikum Kreuzschwestern Wels, July 2006

Sponsored by:	Klinikum Kreuzschwestern Wels
Information provided by:	Klinikum Kreuzschwestern Wels
ClinicalTrials.gov Identifier:	NCT00354588

Purpose

Cardiovascular risk is high in patients with renal failure.
Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure

Condition
Chronic Renal Failure Arterial Stiffness Arterial Wave Reflections

MedlinePlus related topics: Kidney Failure

Study Type:	Observational
Study Design:	Natural History, Longitudinal, Defined Population, Prospective Study
Official Title:	Observational Study on the Prognostic Significance (Renal and Cardiovascular) of Arterial Stiffness and Arterial Wave Reflections in Patients With Mild to Moderate Renal Impairment

Further study details as provided by Klinikum Kreuzschwestern Wels:

Estimated Enrollment:	250
Study Start Date:	January 2006
Estimated Study Completion Date:	December 2010

Eligibility

Criteria

Inclusion Criteria:

chronic renal failure patients (KDOQI III, IV) undergoing regular control visits at our nephrology department
> 19 years
written informed consent

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00354588

Contacts

Contact: Thomas Weber, MD

0043 7242 415 2215

Locations

Austria
Cardiology and Nephrology Department Klinikum Wels	Recruiting
Wels, Austria, 4600
Principal Investigator: Thomas Weber, MD
Cardiology and Nephrology Departments University Graz	Recruiting
Graz, Austria
Contact: Sabine Horn, Prof
Principal Investigator: Sabine Horn, Prof
Principal Investigator: Robert Zweiker, Prof

Sponsors and Collaborators

Klinikum Kreuzschwestern Wels

Investigators

Principal Investigator:	Thomas Weber, MD	Cardiology Department, Klinikum Wels, Austria
Principal Investigator:	Manfred Wallner, MD	Nephrology Department, Klinikum Wels, Austria

More Information

Study ID Numbers:	WelsEK 206
Study First Received:	July 19, 2006
Last Updated:	July 19, 2006
ClinicalTrials.gov Identifier:	NCT00354588
Health Authority:	Austria: Government of Upper Austria, Social Department

Keywords provided by Klinikum Kreuzschwestern Wels:

chronic renal failure
arterial stiffness
arterial wave reflections

Study placed in the following topic categories:

Renal Insufficiency
Urologic Diseases
Renal Insufficiency, Chronic

Kidney Failure, Chronic
Kidney Diseases
Kidney Failure

ClinicalTrials.gov processed this record on January 14, 2009