The Effect of Beer, Red Wine and Fruit Juice on Blood Vessel Function in Persons With Cardiovascular Disease

This study is ongoing, but not recruiting participants.

Sponsored by:	Aalborg Hospital
Information provided by:	Aalborg Hospital
ClinicalTrials.gov Identifier:	NCT00382551

Purpose

To study the effect of red wine, beer and fruit juice on endothelial function in patients with coronary Heart disease

Condition	Intervention	Phase
Coronary Heart Disease	Behavioral: Moderate daily consumption of Red wine Behavioral: Moderate daily consumption of beer Behavioral: Moderate consumption of fruit juice rich in polyphenolics	Phase 0

MedlinePlus related topics: Coronary Artery Disease Heart Diseases

Drug Information available for: Ethanol

Study Type:	Interventional
Study Design:	Prevention, Randomized, Open Label, Uncontrolled, Crossover Assignment, Efficacy Study
Official Title:	The Effect of Alcohol and Polyphenolic Compounds on Endothelial Function

Further study details as provided by Aalborg Hospital:

Primary Outcome Measures:

Changes in flow-mediated vasodilation after 2 weeks intervetion compared with baseline

Secondary Outcome Measures:

Lipid status after 2 weeks intervention compared with baseline
Effects in Coagulation factors after 2 weeks intervention
Effects on markers of inflammation after 2 weeks intervention
Effects on markers of endothelial function after 2 weeks intervention
Changes in the overall antioxidant activity in plasma after 2 weeks intervention

Estimated Enrollment:	50
Study Start Date:	October 2006

Eligibility

Criteria

Inclusion Criteria:

Men or postmenopausal women with stable coronary heart disease
Coronary heart disease should be verifided by coronary angiography with at least 50% stenois in at least one coronary vessel.

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00382551

Locations

Denmark
Department of Cardiology, Aalborg Hospital, Science and Innovation Center
Aalborg, Denmark, 9000

Sponsors and Collaborators

Aalborg Hospital

Investigators

Study Director:

Erik B Schmidt, Professor

Department of Cardiology, Aalborg Hospital , Aarhus University Hospital

More Information

Study ID Numbers:	VN-20060043
Study First Received:	September 28, 2006
Last Updated:	April 3, 2007
ClinicalTrials.gov Identifier:	NCT00382551
Health Authority:	Denmark: National Board of Health; Denmark: Ethics Committee

Keywords provided by Aalborg Hospital:

Alcohol
Red wine
Endothelial function
Flow-mediated vasodilation
Cardiovascular disease

Study placed in the following topic categories:

Arterial Occlusive Diseases
Coronary Disease
Heart Diseases
Myocardial Ischemia
Vascular Diseases

Arteriosclerosis
Ischemia
Coronary Artery Disease
Ethanol

Additional relevant MeSH terms:

Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 14, 2009