Randomised Double Blind Placebo Controlled Cross Over Design of the Efficacy of Topical Morphine for Inflammatory Pain in Children With Epidermolysis Bullosa

This study has been completed.

Sponsored by:	Institute of Child Health
Information provided by:	Institute of Child Health
ClinicalTrials.gov Identifier:	NCT00231517

Purpose

Randomised Double blind placebo controlled cross over design study of the efficacy of morphine for inflammatory pain in children with Epidermolysis Bullosa

Condition	Intervention	Phase
Epidermylosis Bullosa	Drug: topical opiod Drug: morphine sulphate in intrasite gel	Phase IV

Genetics Home Reference related topics: epidermolysis bullosa simplex

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Active Control, Crossover Assignment, Efficacy Study

Eligibility

Ages Eligible for Study:	4 Years to 18 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

children under 18 years epidermolysis wounds requiring dressing changes

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00231517

Locations

United Kingdom
Great Ormond Street Hospital and the Institute of Child health
London, United Kingdom, WC1N 1EH

Sponsors and Collaborators

Institute of Child Health

Investigators

Principal Investigator:

Richard Howard, Prof

Institute of Child Health

More Information

Study ID Numbers:	01MH17
Study First Received:	October 3, 2005
Last Updated:	October 11, 2006
ClinicalTrials.gov Identifier:	NCT00231517
Health Authority:	United Kingdom: Research Ethics Committee

Study placed in the following topic categories:

Morphine
Epidermolysis bullosa
Skin Diseases, Vesiculobullous
Genetic Diseases, Inborn
Skin Diseases

Skin Abnormalities
Pain
Epidermolysis Bullosa
Congenital Abnormalities
Skin Diseases, Genetic

Additional relevant MeSH terms:

Sensory System Agents
Therapeutic Uses
Physiological Effects of Drugs
Central Nervous System Depressants
Narcotics

Peripheral Nervous System Agents
Analgesics
Central Nervous System Agents
Pharmacologic Actions
Analgesics, Opioid

ClinicalTrials.gov processed this record on January 14, 2009