Fundus Changes in the Microphthalmy Eyes - Full Text View

Sponsored by:	Hospital de Olhos Sadalla Amin Ghanem
Information provided by:	Hospital de Olhos Sadalla Amin Ghanem
ClinicalTrials.gov Identifier:	NCT00811512

Purpose

The goal is to describe the fundamental aspects of fundoscopic eye in patients with microphthalmia

Condition
Eye Diseases, Hereditary

Genetics Home Reference related topics: Lenz microphthalmia syndrome oculofaciocardiodental syndrome Peters plus syndrome

MedlinePlus related topics: Eye Diseases

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Retrospective
Official Title:	Fundus Changes in the Microphthalmy Eyes

Further study details as provided by Hospital de Olhos Sadalla Amin Ghanem:

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	3
Study Start Date:	May 2007
Study Completion Date:	October 2008
Primary Completion Date:	September 2008 (Final data collection date for primary outcome measure)

Detailed Description:

Microphthalmos is a developmental ocular disorder defined as a small eyeball. The condition can be associated with abnormalities of anterior and posterior segments. The most common anterior characteristics include corneal opacities, angle-closure and a shallow anterior chamber and cataract. The main findings of posterior segment are uveal effusion, retinal folds, abnormalities of macular capillary vascularization, absence of foveal depression and peripheral retinoschisis. We performed on 3 patients with microphthalmos and their OCT features of posterior segment.

Eligibility

Ages Eligible for Study:	10 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes
Sampling Method:	Non-Probability Sample

Study Population

the study is the description of three cases of microphthalmy with changes to fund of the eye, all documented with optical coherence tomography and clinical characteristics.

Criteria

Inclusion Criteria:

Clinical diagnosis of microphthalmia

Exclusion Criteria:

Eyes larger than 18mm

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00811512

Sponsors and Collaborators

Hospital de Olhos Sadalla Amin Ghanem

Investigators

Principal Investigator:

Fernando J Novelli, Bsc

Hospital de Olhos Sadalla Amin Ghanem

More Information

Responsible Party:	Fernando Jose De Novelli ( Fernando Jose De Novelli )
Study ID Numbers:	sadalla1
Study First Received:	December 18, 2008
Last Updated:	December 18, 2008
ClinicalTrials.gov Identifier:	NCT00811512
Health Authority:	Brazil: Ethics Committee

Keywords provided by Hospital de Olhos Sadalla Amin Ghanem:

retina
fold
fovea

Study placed in the following topic categories:

Genetic Diseases, Inborn
Eye Diseases
Eye Diseases, Hereditary

ClinicalTrials.gov processed this record on January 14, 2009