To Determine the Feasibility of a Clinical Trial Comparing Anticoagulants Versus Antiplatelets in the Acute Treatment of Patients With Cervical Artery Dissection

This study is currently recruiting participants.

Verified by St George's, University of London, September 2005

Sponsors and Collaborators:	St George's, University of London The Stroke Association
Information provided by:	St George's, University of London
ClinicalTrials.gov Identifier:	NCT00238667

Purpose

This is a feasibility study to determine if a sufficient number of patients can be recruited throughout the United Kingdom and whether sufficient endpoints can be generated for a full scale therapeutic trial of anticoagulants versus antiplatelets in acute cervical artery dissection treatment.

Condition
Cervical Artery Dissection Carotid Artery Dissection Vertebral Artery Dissection Stroke

MedlinePlus related topics: Blood Thinners

U.S. FDA Resources

Study Type:	Observational
Study Design:	Longitudinal, Defined Population, Prospective Study
Official Title:	Cervical Artery Dissection in Stroke Study

Further study details as provided by St George's, University of London:

Estimated Enrollment:

250

Show Detailed Description

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Extracranial carotid or vertebral artery dissection with symptom onset within the last 7 days. This includes:
1. Ipsilateral transient ischemic attack or stroke
2. Ipsilateral Horner's syndrome or neck pain with known date of onset.
Imaging evidence of definite or probable dissection on MRI/MRA, CTA or ultrasound.

Exclusion Criteria:

Intracranial cerebral artery dissection
Symptom onset after 7 days
Contraindication to either antiplatelet agents or anticoagulation therapy
Patient's refusal to consent
Patients who are undergoing angiography and stenting or surgery for treatment of their dissection.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00238667

Locations

United Kingdom, England
St. George's University of London, Clinical Neuroscience Department, Cranmer Terrace	Recruiting
London, England, United Kingdom, SW17 0RE
Contact: Dr. Ranjith K Menon, MRCP 0447786257463 rmenon@sgul.ac.uk
Principal Investigator: Professor John W Norris, MD, FRCP

Sponsors and Collaborators

St George's, University of London

The Stroke Association

Investigators

Principal Investigator:	Professor John W Norris, MD, FRCP	St George's, University of London
Principal Investigator:	Professor Hugh Markus, DM, FRCP	St George's, University of London

More Information

Related Info This link exits the ClinicalTrials.gov site

Study ID Numbers:	CAMER5UA, 04/Q0803/113, 04.0287, 04/Q0803/15, 04/Q0803/215, TSA2004/16
Study First Received:	October 11, 2005
Last Updated:	October 16, 2006
ClinicalTrials.gov Identifier:	NCT00238667
Health Authority:	United Kingdom: Research Ethics Committee

Keywords provided by St George's, University of London:

Extracranial carotid artery dissection
Dissection and stroke

Study placed in the following topic categories:

Cerebral Infarction
Aneurysm
Stroke
Vascular Diseases
Wounds and Injuries
Central Nervous System Diseases
Disorders of Environmental Origin

Trauma, Nervous System
Brain Diseases
Cerebrovascular Disorders
Vertebral Artery Dissection
Aneurysm, Dissecting
Cerebrovascular Trauma

Additional relevant MeSH terms:

Nervous System Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 14, 2009