The Effect Of Light On Scar Appearance - Full Text View

Sponsored by:	Northwestern University
Information provided by:	Northwestern University
ClinicalTrials.gov Identifier:	NCT00544635

Purpose

The goal of this project is to examine the ability of light exposure to improve the appearance of cutaneous scars.

Condition	Intervention
Cutaneous Scars	Device: no intervention Device: light

MedlinePlus related topics: Scars

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Placebo Control, Single Group Assignment, Efficacy Study
Official Title:	The Effect Of Light On Scar Appearance

Further study details as provided by Northwestern University:

Primary Outcome Measures:

Scar vascularity [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
Scar pigmentation [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
Scar thickness [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
Scar length [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
Scar width [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
Scar surface area [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment:	50
Study Start Date:	November 2005
Estimated Study Completion Date:	December 2008
Estimated Primary Completion Date:	December 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
A: Experimental scars will be treated with light	Device: light scars will be treated with light
B: Placebo Comparator no intervention	Device: no intervention no intervention

Detailed Description:

Light would be efficacious in improving scar appearance due to its known effects on wound healing, acne, and its use for skin rejuvenation. Light interacts with cells and stimulates the production of new collagen and elastin. This same energy can be used to inhibit collagen formation and help improve scars.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Have two lesions that have been selected for excision
Have two cutaneous scars from previous excisions as part of a standard of care
Subjects are in good health
Subject has a willingness and the ability to understand and provide informed consent for the use of their tissue and communicate with the investigator

Exclusion Criteria:

Pregnancy or lactation
Subjects who are unable to understand the protocol or to give informed consent
Subjects with mental illness

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00544635

Locations

United States, Illinois
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611

Sponsors and Collaborators

Northwestern University

Investigators

Principal Investigator:

Murad Alam, MD

Northwestern University

More Information

Responsible Party:	Northwestern University ( Murad Alam, MD )
Study ID Numbers:	1253-010
Study First Received:	October 12, 2007
Last Updated:	October 3, 2008
ClinicalTrials.gov Identifier:	NCT00544635
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Skin Diseases
Cicatrix

ClinicalTrials.gov processed this record on January 14, 2009