Repository: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant

This study has been completed.

Sponsored by:	Vanderbilt University
Information provided by:	Vanderbilt University
ClinicalTrials.gov Identifier:	NCT00179075

Purpose

This is a repository to store blood and stem cell samples for future research.

Condition
Hematopoietic Stem Cell Transplantation Graft vs Host Disease

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Prospective
Official Title:	Repository for Study: Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)

Further study details as provided by Vanderbilt University:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	100
Study Start Date:	April 2003
Study Completion Date:	April 2008

Detailed Description:

Our Hypothesis is that the graft-versus-tumor effect can be enhanced while minimizing the complications of GVHD by determining the qualitative and quantitative changes in T regulatory cells throughout the transplant process. Our understanding of this can lead to new treatment strategies and improved clinical therapeutic implications.

Eligibility

Ages Eligible for Study:	18 Years to 70 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Criteria

Inclusion Criteria:

Patients 18-70 years old undergoing either autologous transplant or allogeneic transplant for various hematologic conditions

Exclusion Criteria:

Patients < 18 or > 70 years old undergoing either autologous transplant or allogeneic transplant

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00179075

Locations

United States, Tennessee
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232

Sponsors and Collaborators

Vanderbilt University

Investigators

Principal Investigator:

Adetola A Kassim, MD

Vanderbilt University

More Information

Responsible Party:	Vanderbilt University ( Adetola A. Kassim, MD )
Study ID Numbers:	BMT 030263
Study First Received:	September 13, 2005
Last Updated:	December 12, 2008
ClinicalTrials.gov Identifier:	NCT00179075
Health Authority:	United States: Institutional Review Board

Keywords provided by Vanderbilt University:

T-Lymphocyte Subsets

Study placed in the following topic categories:

Graft versus host disease
Graft vs Host Disease
Homologous wasting disease

Additional relevant MeSH terms:

Immune System Diseases

ClinicalTrials.gov processed this record on January 14, 2009