Study of Gated External-Beam Radiotherapy for Internal, Extra-Cranial Tumors

This study is currently recruiting participants.

Verified by University of Rochester, September 2006

Sponsored by:	University of Rochester
Information provided by:	University of Rochester
ClinicalTrials.gov Identifier:	NCT00178477

Purpose

The purpose of this research study is to evaluate the use of breath-holding during the radiation treatment of lung and liver tumors as a means to correct for the movement of the tumor caused by breathing. A better understanding of the typical tumor motion caused by breathing can help determine whether simple passive breathing and/or breath-holding could be used for the future treatment of similar lung and liver tumors using radiosurgery techniques.

Condition	Intervention
Neoplasm, Metastatic	Procedure: stereotactic body radiation therapy with breath-holding

MedlinePlus related topics: Cancer

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Historical Control, Single Group Assignment, Efficacy Study
Official Title:	Feasibility Study for Gated External-Beam Radiotherapy for Patients With Internal, Extra-Cranial Tumors

Further study details as provided by University of Rochester:

Estimated Enrollment:	48
Study Start Date:	January 2002
Estimated Study Completion Date:	January 2006

Detailed Description:

Must be already enrolled on URCC 8700 or URCC 9700

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

The patient is enrolled on U8700 RSRB # A Phase II Study For Using Radiosurgery On Limited Metastases Of Breast Cancer or U9700 A Pilot Study For Using Radiosurgery On Limited Metastases.

The patient is ≥ 18 years of age

Informed consent is obtained

Exclusion Criteria:

The patient meets inclusion criteria

Contraindications are as for any MRI procedure:

Patients with implanted, large metal objects; pregnant women; and those with adverse reactions to tight spaces will be precluded from participating in this study.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00178477

Contacts

Contact: Paul Okunieff, MD

585-375-5972

paul_okunieff@urmc.rochester.edu

Locations

United States, New York
University of Rochester Department of Radiation Oncology	Recruiting
Rochester, New York, United States, 14642
Contact: Walter O'Dell, PhD 585-275-9996 Walter_odell@urmc.rochester.edu
Sub-Investigator: Paul Okunieff, MD
Sub-Investigator: Alan Katz, MD
Sub-Investigator: Michael Milano, MD

Sponsors and Collaborators

University of Rochester

Investigators

Principal Investigator:

Walter O'Dell, PhD

University of Rochester

More Information

Study ID Numbers:	URCC 3701
Study First Received:	September 13, 2005
Last Updated:	September 6, 2006
ClinicalTrials.gov Identifier:	NCT00178477
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Neoplasm Metastasis

Additional relevant MeSH terms:

Neoplasms
Neoplastic Processes
Pathologic Processes

ClinicalTrials.gov processed this record on January 14, 2009