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Teeth Dosimetry Determination
This study is not yet open for participant recruitment.
Verified by University of Rochester, September 2006
Sponsored by: University of Rochester
Information provided by: University of Rochester
ClinicalTrials.gov Identifier: NCT00178347
  Purpose

Irradiation of any tissue creates changes in that tissue. Ionizing radiation imparts charges to the tissue as it interacts with tissue components, changing the tissue structure. The specific type of modification also depends to some extent upon the type of tissue irradiated. It has been shown that it is possible to read the tooth enamel irradiation record using techniques such as electron paramagnetic resonance (EPR), or electron spin resonance (ESR).

It is proposed to examine radiation responses in approximately one hundred (100) human teeth. This would include teeth free of, as well as those containing, amalgam (silver) restorations. For the first group, teeth that have already been collected (pre-existing pathological specimens) would be used. These teeth were surgical/pathological discards collected without identifiers by the dental providers.


Condition Intervention
Radiation Tolerance
Procedure: Exposure to irradiation (for example, dental X-rays)

Drug Information available for: X-Rays
U.S. FDA Resources
Study Type: Observational
Study Design: Cross-Sectional, Convenience Sample, Retrospective Study
  Eligibility

Genders Eligible for Study:   Both
Criteria

Inclusion Criteria:

  • Discarded pathologic specimens (teeth)
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00178347

Contacts
Contact: Paul Okunieff, MD paul_okunieff@urmc.rochester.edu

Locations
United States, New York
University of Rochester, Dept. Radiation Oncology
Rochester, New York, United States, 14642
Sponsors and Collaborators
University of Rochester
Investigators
Study Chair: Paul Okunieff, MD University of Rochester, Dept. of Radiation Oncology
  More Information

Study ID Numbers: URCC 11070
Study First Received: September 12, 2005
Last Updated: September 6, 2006
ClinicalTrials.gov Identifier: NCT00178347  
Health Authority: United States: Institutional Review Board

ClinicalTrials.gov processed this record on January 14, 2009