Home
Search
Study Topics
Glossary
|
|
|
|
|
|
Sponsors and Collaborators: |
Beth Israel Medical Center Solvay Pharmaceuticals St. Luke's-Roosevelt Hospital Center University of Iowa University of Delaware Ohio State University |
---|---|
Information provided by: | Beth Israel Medical Center |
ClinicalTrials.gov Identifier: | NCT00483418 |
The purpose of this study is to survey the total serum testosterone levels in male patients with hormone-independent malignancies. The prevalence of hypogonadism is not known, but is thought to be significant. Results will be adjusted for age and stratified for type of cancer, stage, study site,and presence of opiate use for pain management, which is known to reduce testosterone levels.
Condition |
---|
Hypogonadism |
Study Type: | Observational |
Study Design: | Cohort, Cross-Sectional |
Official Title: | Survey of Testosterone Levels in a Diverse Set of Male Patients With Hormone-Independent Cancers |
Estimated Enrollment: | 412 |
Study Start Date: | June 2007 |
Estimated Study Completion Date: | December 2008 |
Estimated Primary Completion Date: | December 2008 (Final data collection date for primary outcome measure) |
Fatigue - extreme tiredness - is associated with cancer as well as its treatment. It has many causes, including the direct effects of the cancer itself, nutritional changes, anemia, changes in activity levels, worry, or, perhaps, hormones such as testosterone. This study is a survey of the amount of testosterone in the blood of men being treated for cancers that are not directly influenced by testosterone (not prostate or testicular tumors).
Testosterone is a hormone that is made by the body from teenage years through adulthood, and helps define male characteristics: sexual function, muscle building, ability to grow hair and deepen the voice. It is believed that the amount of fatigue experienced by men with cancer may be at least and in part due to reduced testosterone levels.
Male cancer patients will be recruited for this study at the time of regularly scheduled visits with their oncologists for treatment or for follow-up care. Patients who agree to participate and sign a consent will be asked to answer questions about their health, medications, vitamins & supplements, and to complete a standardized questionnaire about their quality of life. One tube of blood (8.5 cc) will be drawn at the same time as the other blood tests scheduled for that visit to avoid an additional blood draw. Various elements of the collected information will be compared with the testosterone levels to see if any meaningful patterns exist. The study sample will be drawn from a geographically diverse set of oncology practices in the US. A larger follow-up study is planned if testosterone levels are found to be lower in men with cancer than similar age men without cancer, or if low testosterone levels are associated with more fatigue.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Men with non-hormone dependent cancers who are having blood drawn for other purposes before 12 noon.
Inclusion Criteria:
Exclusion Criteria:
Contact: Victoria Rosenwald, RN MPH | 212 844-8285 | vrosenwa@chpnet.org |
Contact: Stewart B Fleishman, MD | 212 844-6295 | sfleishm@chpnet.org |
United States, New York | |
Beth Israel Medical Center | Recruiting |
New York, New York, United States, 10003 | |
Contact: vr121@columbia.edu 212-844-8285 vr121@columbia.edu | |
Contact: Victoria Rosenwald 212-844-8285 vr121@columbia.edu | |
Sub-Investigator: Victoria Rosenwald |
Principal Investigator: | Stewart B Fleishman, MD | Continuum Cancer Centers of New York |
Responsible Party: | Beth Israel Oncology Research Office ( Victoria Rosenwald RN MPH ) |
Study ID Numbers: | 062-07 |
Study First Received: | June 6, 2007 |
Last Updated: | May 7, 2008 |
ClinicalTrials.gov Identifier: | NCT00483418 |
Health Authority: | United States: Institutional Review Board |
male cancer |
Testosterone Hypogonadism Gonadal Disorders Endocrine System Diseases |
Methyltestosterone Endocrinopathy Testosterone 17 beta-cypionate |
Physiological Effects of Drugs Hormones, Hormone Substitutes, and Hormone Antagonists Hormones Pharmacologic Actions Androgens |