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Sponsors and Collaborators: |
University of Sydney Sydney West Area Health Service |
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Information provided by: | University of Sydney |
ClinicalTrials.gov Identifier: | NCT00261781 |
The major aim of this study is to determine the efficacy of a home-based treadmill walking program in improving walking capacity and quality of life in people with early mid-stage Parkinson's disease(PD).
Condition | Intervention | Phase |
---|---|---|
Idiopathic Parkinson's Disease |
Behavioral: Treadmill training |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Single Blind (Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study |
Official Title: | Does Home-Based Treadmill Training Improve Walking Capacity and Quality of Life in People With Early to Mid-Stage Parkinson's Disease? |
Estimated Enrollment: | 140 |
Study Start Date: | May 2005 |
Estimated Study Completion Date: | December 2009 |
Estimated Primary Completion Date: | December 2009 (Final data collection date for primary outcome measure) |
After Alzheimer's disease, Parkinson's disease (PD) is the most common degenerative neurological condition suffered by Australians, with more than 30,000 Australians having PD at any one time (Parkinson's Australia). Hypokinesia, ie, reduced speed and amplitude of movement, is a major impairment of motor control affecting walking in people with PD. Over time, the development of slow, shuffling walking contributes to loss of independence and falls, with devastating consequences for individuals with PD and their families(Ashburn et al, 2001, Playfer 2001). Any decrease or delay in disability will reduce the personal and financial costs to individuals with PD, their families, health care resources and the community.
A number of previous studies suggest exercise capacity and exercise habits are positively correlated. In people with mild Parkinson's disease (Canning et al 2005), walking capacity, measured as distance walked in the 6-min walk test, correlated with the amount of walking (r=.64, p<0.01) performed each week. Similarly, in an earlier study of people with mild to moderate Parkinson's disease, regular exercise was associated with better exercise capacity (Canning et al 1997). It appears, therefore, that proactive intervention aimed at developing good exercise habits in sedentary individuals with early to mid-stage Parkinson's disease has the potential to reduce or delay walking difficulties.
This study aims to establish the efficacy of a home-based treadmill walking program in providing an early intervention which addresses the primary motor control impairment of hypokinesia, while at the same time maintaining or improving exercise capacity.
Ages Eligible for Study: | 30 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Australia, New South Wales | |
Westmead Hospital | |
Sydney, New South Wales, Australia, 2145 |
Principal Investigator: | Colleen G Canning, PhD | University of Sydney |
Responsible Party: | The University of Sydney ( Dr Colleen Canning ) |
Study ID Numbers: | U3189 |
Study First Received: | December 1, 2005 |
Last Updated: | July 1, 2008 |
ClinicalTrials.gov Identifier: | NCT00261781 |
Health Authority: | Australia: National Health and Medical Research Council |
Treadmill Walking Exercise Automaticity Quality of Life |
Ganglion Cysts Movement Disorders Parkinson Disease Basal Ganglia Diseases Quality of Life |
Central Nervous System Diseases Parkinsonian Disorders Neurodegenerative Diseases Brain Diseases |
Nervous System Diseases |