Effect of Chronic PDE5-Inhibition on Endothelial Function in Diabetics

This study has been completed.

Sponsored by:	IRCCS San Raffaele
Information provided by:	IRCCS San Raffaele
ClinicalTrials.gov Identifier:	NCT00420901

Purpose

chronic PDE5-Inhibition improves endothelial function in diabetics

Condition	Intervention	Phase
Diabetes	Drug: sildenafil	Phase III

MedlinePlus related topics: Diabetes

Drug Information available for: Sildenafil citrate Sildenafil

Study Type:	Interventional
Study Design:	Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study
Official Title:	Effect of Chronic Administration of Sildenafil on Endothelial Function in Men With Diabetes

Further study details as provided by IRCCS San Raffaele:

Primary Outcome Measures:

Secondary Outcome Measures:

Estimated Enrollment:	30
Study Start Date:	January 1999
Estimated Study Completion Date:	February 2000

Detailed Description:

Evaluation of endothelial function at baseline and after chronic administration of sildenafil in male subjects with diabetes

Eligibility

Criteria

Inclusion Criteria:

Exclusion Criteria:

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00420901

Locations

Sponsors and Collaborators

IRCCS San Raffaele

Investigators

Study Director:

giuseppe rosano, md

San Raffaele EUR

More Information

Study ID Numbers:	HSRRM1999/4
Study First Received:	January 9, 2007
Last Updated:	January 9, 2007
ClinicalTrials.gov Identifier:	NCT00420901
Health Authority:	Italy: Ethics Committee

Keywords provided by IRCCS San Raffaele:

function
inhibition

Study placed in the following topic categories:

Metabolic Diseases
Diabetes Mellitus
Endocrine System Diseases
Sildenafil

Endocrinopathy
Metabolic disorder
Glucose Metabolism Disorders

Additional relevant MeSH terms:

Vasodilator Agents
Phosphodiesterase Inhibitors
Molecular Mechanisms of Pharmacological Action
Therapeutic Uses

Enzyme Inhibitors
Cardiovascular Agents
Pharmacologic Actions

ClinicalTrials.gov processed this record on January 14, 2009