Full Text View  
  Tabular View  
  Contacts and Locations  
  No Study Results Posted  
  Related Studies  
Spatial Neglect and Bias in Near and Far Space
This study is currently recruiting participants.
Verified by National Institute of Neurological Disorders and Stroke (NINDS), December 2008
Sponsors and Collaborators: Kessler Medical Rehabilitation Research Center
National Institute of Neurological Disorders and Stroke (NINDS)
Information provided by: National Institute of Neurological Disorders and Stroke (NINDS)
ClinicalTrials.gov Identifier: NCT00350012
  Purpose

The purpose of this research study is to learn how people distribute their visual attention when looking at objects nearby versus far away, and why vision may become distracted at near versus far distances.


Condition
Stroke

MedlinePlus related topics: Rehabilitation
U.S. FDA Resources
Study Type: Observational
Study Design: Case Control, Prospective
Official Title: Spatial Neglect and Bias in Near and Far Space

Further study details as provided by National Institute of Neurological Disorders and Stroke (NINDS):

Biospecimen Retention:   None Retained

Biospecimen Description:

Estimated Enrollment: 400
Study Start Date: May 2004
Estimated Study Completion Date: April 2009
Estimated Primary Completion Date: April 2009 (Final data collection date for primary outcome measure)
Groups/Cohorts
1
Persons who have had a stroke
2
Healthy volunteers

Detailed Description:

Visual distraction is a problem that more often occurs people who have suffered strokes than in the general population. Problems of visual attention generally appear immediately following a stroke, and may impair driving and other functions. While it is thought that there is a natural course of improvement over time, little is known about how this improvement occurs. Some studies suggest that recovery is only partial, meaning certain aspects of visual attention may improve while other aspects remain but escape notice.

The purpose of this study is to examine the effect of stroke on a person's visual attention when looking at objects nearby versus far away, and to learn why a person's visual attention may become more distracted at near versus far distances. The purpose of this study is also to understand how modeled interventions, such as eye patching or prism goggles, affect impairment measures of visual attention.

After an initial screening (including attention, thinking, memory, and visual judgment tests), participants will be given a neurological examination. Participants may be asked to perform visual tasks while wearing an eye patch or prism goggles. Next, they will be asked to perform a line bisection task by looking at lines on a video screen either at close or far distances and, using a laser pointer, marking the center of the lines as they appear on-screen. Participants may be asked to perform other, similar visual tasks as well.

Duration of the study for participants varies, ranging from 1 or 2 sessions totaling approximately 2 hours to multiple sessions spanning a year.

Research from this study may help researchers better understand problems associated with stroke and may lead to therapies designed to promote improved visual attention.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Persons who have had a stroke. Also, healthy volunteers.

Criteria

Inclusion Criteria:

  • The subject has a history of stroke.
  • The subject is 18 to 100 years old.
  • The subject is able to give Informed consent.
  • The subject is post-Stroke with left-hemisphere injury and has no spatial neglect (no attentional imbalance).
  • The subject is post-stroke with right hemisphere damage and has spatial neglect (attentional imbalance).
  • Healthy subject with no brain injury.
  • The subject is post stroke and has hemianopia (a "visual field cut").
  • The subject is able and willing to comply with the study protocol, including availability for all scheduled clinic visits.

Exclusion Criteria:

  • Subjects with brain tumors, head injury with loss of consciousness, visual disorders other than corrected near or far-sightedness, history of learning disabilities, dementia or Alzheimer's Disease.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00350012

Contacts
Contact: Siby Varughese, MA, RN (973) 324-3564

Locations
United States, New Jersey
Kessler Medical Rehabilitation Research and Education Center, 1199 Pleasant Valley Way Recruiting
West Orange, New Jersey, United States, 07052
Contact: Anna M. Barrett, MD     973-324-3569        
Sponsors and Collaborators
Kessler Medical Rehabilitation Research Center
Investigators
Principal Investigator: Anna M. Barrett, MD Stroke Rehabilitation Research, Kessler Medical Rehabilitation Research and Education Center
  More Information

Responsible Party: Kessler Medical Rehabilitation Research and Education Center ( Anna M. Barrett, MD, Behavioral Neurology/Cognitive Rehabilitation Associate Professor of Physical Medicine and Rehabilitation, and Neurology and Neurosciences, UMDNJ--NJMS Director, Stroke Rehabilitation Research )
Study ID Numbers: K02NS047009
Study First Received: July 6, 2006
Last Updated: December 9, 2008
ClinicalTrials.gov Identifier: NCT00350012  
Health Authority: United States: Federal Government

Keywords provided by National Institute of Neurological Disorders and Stroke (NINDS):
stroke
visual
spatial neglect

Study placed in the following topic categories:
Cerebral Infarction
Stroke
Vascular Diseases
Central Nervous System Diseases
Brain Diseases
Cerebrovascular Disorders

Additional relevant MeSH terms:
Nervous System Diseases
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 14, 2009