DISEASE CHARACTERISTICS:

• Histologically documented and completely resected stage III or stage IV renal cell carcinoma, clinically staged within 2 months prior to initiation of therapy
• No evidence of nephrotic syndrome

PATIENT CHARACTERISTICS:

Age:

• Over 16

Performance status:

• ECOG 0-2

Hematopoietic:

• WBC at least 3,000/mm^3
• Granulocyte count at least 1,500/mm^3
• Platelet count 50,000/mm3 to 500,000/mm^3
• Hemoglobin at least 10 g/dL
• No hematologic abnormalities

Hepatic:

• PT no greater than 1.5 times control
• PTT less than 1.5 times control
• Hepatitis B surface antigen negative

Renal:

• Creatinine no greater than 4.0 mg/dL
• Calcium no greater than 12 mg/dL
• No symptomatic hypercalcemia

Cardiovascular:

• No uncontrolled or severe cardiac disease, e.g.:

  • No myocardial infarction within 6 months
  • No congestive heart failure

Other:

• HIV negative
• No significant organ dysfunction
• No other serious medical illness that would limit life expectancy
• No significant CNS disease including uncontrolled or untreated psychiatric or seizure disorders
• No uncontrolled bacterial, viral, or fungal infection
• No active peptic or duodenal ulcer
• Adequate peripheral venous access required
• No prior malignancy within past 5 years except inactive nonmelanoma skin cancer or carcinoma in situ of the cervix
• Not pregnant
• Negative pregnancy test

PRIOR CONCURRENT THERAPY:

• No other concurrent postnephrectomy adjuvant therapy

Biologic therapy:

• No concurrent immunotherapy

Chemotherapy:

• No concurrent chemotherapy

Endocrine therapy:

• More than 1 week since prior corticosteroids (except as inhalation therapy for respiratory ailments or replacement for adrenal insufficiency)

• No concurrent therapy with the following:

  • Estrogens (except as postmenopausal replacement therapy)
  • Androgens
  • Progestins
  • Antiestrogens
  • Antiandrogens
  • LHRH analogues or antagonists
  • Other hormones

Radiotherapy:

• Not specified

Surgery:

• See Disease Characteristics
• No prior solid organ allograft
• More than 3 weeks since major surgery, including nephrectomy