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Sponsored by: |
Ligand Pharmaceuticals |
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Information provided by: | NIH AIDS Clinical Trials Information Service |
ClinicalTrials.gov Identifier: | NCT00002212 |
The purpose of this study is to see if it is safe and effective to give Targretin capsules to patients with AIDS-related Kaposi's sarcoma (KS).
Condition | Intervention | Phase |
---|---|---|
Sarcoma, Kaposi HIV Infections |
Drug: Bexarotene |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment, Safety Study |
Official Title: | Phase II Evaluation of Targretin Capsules in Patients With AIDS-Related Kaposi's Sarcoma |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria
Patients must have:
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions or symptoms are excluded:
Concurrent Medication:
Excluded:
Concurrent Treatment:
Excluded:
Radiotherapy, cryotherapy, photodynamic therapy, and/or laser therapy for any KS indicator lesion.
Prior Medication:
Excluded:
Prior Treatment:
Excluded:
United States, California | |
Desert Univ School of Medicine | |
Palm Springs, California, United States, 92262 | |
United States, Louisiana | |
Tulane Univ School of Medicine | |
New Orleans, Louisiana, United States, 70112 | |
United States, Pennsylvania | |
Milton S Hershey Med Ctr | |
Hershey, Pennsylvania, United States, 17033 |
Study ID Numbers: | 287A, L1069-21 |
Study First Received: | November 2, 1999 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00002212 |
Health Authority: | United States: Food and Drug Administration |
Sarcoma, Kaposi Acquired Immunodeficiency Syndrome Anticarcinogenic Agents |
Sexually Transmitted Diseases, Viral Malignant mesenchymal tumor Acquired Immunodeficiency Syndrome Sarcoma, Kaposi Soft tissue sarcomas Immunologic Deficiency Syndromes Herpesviridae Infections Virus Diseases |
Neoplasms, Connective and Soft Tissue Kaposi sarcoma Bexarotene HIV Infections Sexually Transmitted Diseases Sarcoma DNA Virus Infections Retroviridae Infections |
Anticarcinogenic Agents RNA Virus Infections Slow Virus Diseases Neoplasms by Histologic Type Immune System Diseases Antineoplastic Agents Physiological Effects of Drugs |
Infection Protective Agents Pharmacologic Actions Neoplasms Therapeutic Uses Lentivirus Infections Neoplasms, Vascular Tissue |