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| Sponsored by: |
Emory University |
|---|---|
| Information provided by: | Emory University |
| ClinicalTrials.gov Identifier: | NCT00599014 |
Purpose
Heart failure is a very common cause of hospital admission and there are half a million new cases diagnosed each year in the United States. While some important progress has been made over the last two decades for the treatment of heart failure, there still remains a critical need for further advances in our understanding of this disease in order to significantly improve patient outcomes. Large numbers of heart failure patients need to be studied over time to allow scientists to investigate those factors that influence the responses to therapy.
| Condition |
|---|
|
Heart Failure |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
| Official Title: | The Atlanta Cardiomyopathy Consortium |
Blood for DNA/RNA/Proteomics analysis and Urine for proteomic analysis
| Estimated Enrollment: | 1000 |
| Study Start Date: | November 2007 |
| Estimated Study Completion Date: | December 2011 |
| Estimated Primary Completion Date: | December 2011 (Final data collection date for primary outcome measure) |
In this study information will be collected on patients with heart failure and their progress and outcomes will be followed over time. The aim is to understand the natural history, risk factors for improvement or progression, and determinants of response to therapy for heart failure. Of interest are many aspects of heart failure including genetic influences, quality of life issues, how individuals cope with feelings about having heart disease, and how they manage their day-to-day symptoms etc.. A database will be created of approximately 1,000 heart failure patients from Emory, Crawford Long, Wesley Woods, Grady, and the VA Medical Center.
This is strictly an observational study and subjects will not be receiving any experimental therapy nor will their routine medical care be affected in any way. Data to be collected includes:
After collecting data, a variety of statistical tests will be run to analyze factors that influence heart failure patients' responses to treatment. The results of this analysis will be used to optimize therapy for future heart failure patients.
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Cardiology and general medicine clinics; Inpatients from cardiology services
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Maureen O Lobb, PhD, RN | 404-712-7838 | omauree@emory.edu |
| Contact: LaRonica McPherson, BSN | 404-778-3846 | LaRonica.McPherson@emoryhealthcare.org |
| United States, Georgia | |
| Emory University | Recruiting |
| Atlanta, Georgia, United States, 30322 | |
| Study Director: | Greg Giamouzis, MD | Emory University |
More Information
| Responsible Party: | Associate Professor of Medicine (cardiology) Emory University ( Principal Investigator: Javed Butler, MD, MPH ) |
| Study ID Numbers: | 5380 |
| Study First Received: | January 11, 2008 |
| Last Updated: | January 22, 2008 |
| ClinicalTrials.gov Identifier: | NCT00599014 |
| Health Authority: | United States: Institutional Review Board |
|
Cardiomyopathy, heart failure, DNA, echocardiography, messenger RNA, natural history |
|
Heart Failure Heart Diseases Cardiomyopathies |
|
Cardiovascular Diseases |
