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Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma
This study is currently recruiting participants.
Verified by Cedars-Sinai Medical Center, January 2008
Sponsored by: Cedars-Sinai Medical Center
Information provided by: Cedars-Sinai Medical Center
ClinicalTrials.gov Identifier: NCT00598949
  Purpose

The purpose of the study is to determine genetic links among blood-relatives and between spouses of patients with pituitary tumors.


Condition
Pituitary Adenoma

MedlinePlus related topics: Cancer
U.S. FDA Resources
Study Type: Observational
Study Design: Family-Based, Prospective
Official Title: Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma

Further study details as provided by Cedars-Sinai Medical Center:

Biospecimen Retention:   Samples With DNA

Biospecimen Description:

cell lines are established for future genetic analysis


Estimated Enrollment: 600
Study Start Date: January 2003
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
Detailed Description:

The purpose of the family study is to investigate the genetic basis for the development of pituitary tumors by assessing the prevalence of pituitary tumors in relatives of probands with the disease as compared to the prevalence in unrelated spouses sharing a similar environment.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

tertiary referral center

Criteria

Inclusion Criteria:

  • patients harboring secretory or non-secretory adenomas and/or siblings and/or spouses

Exclusion Criteria:

  • patient without consenting siblings and/or siblings and/or spouses
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00598949

Contacts
Contact: Vivien Bonert, MD 310-423-2830 Bonertv@cshs.org
Contact: Alexis Jacobs, RN, BSN 310-423-3395 Alexis.Jacobs@cshs.org

Locations
United States, California
Cedars-Sinai Medical Center, Pituitary Center Recruiting
Los Angeles, California, United States, 90048
Contact: Vivien Bonert, MD     310-423-2830     Bonertv@cshs.org    
Contact: Alexis Jacobs, RN, BSN     310-423-3395     Alexis.Jacobs@cshs.org    
Sponsors and Collaborators
Cedars-Sinai Medical Center
Investigators
Principal Investigator: Vivian Bonert, MD Cedars-Sinai Medical Center
  More Information

Responsible Party: Cedars-Sinai Medical Center, Pituitary Center ( Vivien Bonert, MD )
Study ID Numbers: 3765, 3765
Study First Received: January 11, 2008
Last Updated: January 11, 2008
ClinicalTrials.gov Identifier: NCT00598949  
Health Authority: United States: Institutional Review Board

Keywords provided by Cedars-Sinai Medical Center:
pituitary adenoma

Study placed in the following topic categories:
Hypothalamic Diseases
Pituitary Diseases
Central Nervous System Diseases
Endocrine System Diseases
Pituitary Neoplasms
Central Nervous System Neoplasms
Brain Diseases
Supratentorial Neoplasms
Brain Neoplasms
Endocrinopathy
Adenoma
Nervous System Neoplasms
Neoplasms, Glandular and Epithelial
Endocrine Gland Neoplasms

Additional relevant MeSH terms:
Neoplasms
Neoplasms by Site
Neoplasms by Histologic Type
Hypothalamic Neoplasms
Nervous System Diseases

ClinicalTrials.gov processed this record on January 14, 2009