Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

This study is currently recruiting participants.

Verified by Istanbul Science University, December 2007

Sponsors and Collaborators:	Istanbul Science University Group Florence Nightingale
Information provided by:	Istanbul Science University
ClinicalTrials.gov Identifier:	NCT00571090

Purpose

The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.

Condition	Intervention
Thyroid Nodule	Procedure: Thyroid ultrasonography

MedlinePlus related topics: Cancer Thyroid Cancer Ultrasound

Drug Information available for: Thyroid

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case-Only, Cross-Sectional
Official Title:	Evaluation of Thyroid Fine Needle Aspiration Biopsies: Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules

Further study details as provided by Istanbul Science University:

Primary Outcome Measures:

Thyroid cancer [ Time Frame: one year ] [ Designated as safety issue: No ]

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	1000
Study Start Date:	June 2003
Estimated Study Completion Date:	December 2009

Groups/Cohorts	Assigned Interventions
Thyroid nodule Subjects who present with thyroid nodules will be enrolled into the study. Euthyroid and hypothyroid subjects with a solitary thyroid nodule or multinodular goiter will be enrolled. For subjects with a suppressed TSH, a thyroid scan will be performed. Subjects with a hypoactive nodule in the thyroid scan and a low TSH will be enrolled.	Procedure: Thyroid ultrasonography Ultrasound-guided thyroid fine-needle aspiration biopsy

Eligibility

Ages Eligible for Study:	15 Years to 89 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Endocrinology Clinic

Criteria

Inclusion Criteria:

Subjects with thyroid nodules over 10 mm in the longest diameter
Euthyroid or hypothyroid subjects with a solitary thyroid nodule or multinodular goiter
Subjects with a hypoactive nodule in the thyroid scan and a low TSH

Exclusion Criteria:

Subjects with four or more thyroid nodules that are over 10 mm
Subjects with low TSH and hyperactive nodule on thyroid scan

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00571090

Contacts

Contact: Ahmet Selcuk Can, MD

90-212-2883400 ext 4321

selcukcan@endokrinoloji.com

Locations

Turkey
Group Florence Nightingale	Recruiting
Istanbul, Turkey
Principal Investigator: Ahmet Selcuk Can, MD

Sponsors and Collaborators

Istanbul Science University

Group Florence Nightingale

Investigators

Principal Investigator:

Ahmet Selcuk Can, MD

Istanbul Science University and Group Florence Nightingale

More Information

Responsible Party:	Metropolitan Florence Nightingale Hospital ( Ahmet Selcuk Can, MD )
Study ID Numbers:	B.30.2.IBU.0.01.00.00/511, 511
Study First Received:	December 10, 2007
Last Updated:	December 10, 2007
ClinicalTrials.gov Identifier:	NCT00571090
Health Authority:	Turkey: Ministry of Health

Keywords provided by Istanbul Science University:

Thyroid nodule
Biopsy, Fine-Needle

Study placed in the following topic categories:

Thyroid Nodule
Thyroid Neoplasms
Head and Neck Neoplasms
Endocrine System Diseases

Endocrinopathy
Thyroid Diseases
Endocrine Gland Neoplasms

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site

ClinicalTrials.gov processed this record on January 13, 2009