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| Sponsors and Collaborators: |
The Alfred La Trobe University Austin Hospital, Melbourne Australia Victorian Tuberculosis and Lung Association |
|---|---|
| Information provided by: | The Alfred |
| ClinicalTrials.gov Identifier: | NCT00168285 |
Purpose
Interstitial lung disease (ILD) is a highly disabling group of conditions including idiopathic pulmonary fibrosis (IPF), acute and chronic interstitial pneumonias, connective tissue diseases and sarcoidosis. People with ILD frequently experience breathlessness on exertion, which limits their ability to undertake daily activities. People with ILD report very poor quality of life due to low levels of physical functioning and vitality, and high levels of breathlessness and fatigue. There are few treatments for ILD and those that are available have limited impact on quality of life.
The aim of this study is to assess the effects of Pulmonary Rehabilitation, which consists of specialised exercise training for people with lung disease, on exercise capacity and quality of life in people with ILD. We hypothesis that exercise training will result in reduced dyspnoea, improved exercise tolerance and enhanced quality of life.
| Condition | Intervention |
|---|---|
|
Interstitial Lung Disease |
Behavioral: Pulmonary Rehabilitation |
| Study Type: | Interventional |
| Study Design: | Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Safety/Efficacy Study |
| Official Title: | Pulmonary Rehabilitation in Interstitial Lung Disease - a Multi-Centre, Single-Blinded Randomised Controlled Trial |
| Estimated Enrollment: | 56 |
| Study Start Date: | March 2005 |
| Estimated Study Completion Date: | May 2007 |
Interstitial lung disease (ILD) is a highly disabling group of conditions including idiopathic pulmonary fibrosis (IPF), acute and chronic interstitial pneumonias, connective tissue diseases and sarcoidosis. People with ILD frequently experience breathlessness on exertion, which limits their ability to undertake daily activities and reduces health-related quality of life.Available treatments for ILD have proved largely ineffective, offering no improvement in survival and demonstrating only limited impact on quality of life.
Aims of the Research
Comparisons: 8 weeks exercise training compared to control group (maximal exercise capacity, functional exercise capacity, dyspnoea, quality of life).
Eligibility| Ages Eligible for Study: | 40 Years to 90 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Australia, Victoria | |
| Alfred Hospital | |
| Melbourne, Victoria, Australia, 3004 | |
| Austin Hospital | |
| Melbourne, Victoria, Australia, 3084 | |
| Principal Investigator: | Anne E Holland, PhD | Alfred Hospital and LaTrobe University |
| Principal Investigator: | Matthew Conron, MBBS | The Alfred |
| Principal Investigator: | Prue Munro, BAppSc | The Alfred |
| Principal Investigator: | Christine McDonald, MBBS PhD | Austin Hospital, Melbourne Australia |
| Principal Investigator: | Catherine Hill, PhD | Austin Hospital, Melbourne Australia |
More Information
| Study ID Numbers: | PRIDe |
| Study First Received: | September 13, 2005 |
| Last Updated: | April 4, 2007 |
| ClinicalTrials.gov Identifier: | NCT00168285 |
| Health Authority: | Australia: National Health and Medical Research Council |
|
Exercise Pulmonary rehabilitation Idiopathic pulmonary fibrosis Connective tissue disorders |
|
Lung Diseases, Interstitial Respiratory Tract Diseases Fibrosis Hamman-Rich syndrome |
Lung Diseases Connective Tissue Diseases Pulmonary Fibrosis |
