Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes - Full Text View

Sponsored by:	John H. Stroger Hospital
Information provided by:	John H. Stroger Hospital
ClinicalTrials.gov Identifier:	NCT00718198

Purpose

This study is a retrospective cross-sectional study at one institution, where the investigators compared diabetic patients admitted to Medicine Services from March-April 2006 (before CPOE was implemented) to patients admitted from October-November 2007 (one year after CPOE implementation). Capillary blood glucose values, Hemoglobin AIC, diabetes medication profile and demographic data were obtained to compare between groups. The investigators hypothesized that a computer-based protocol that emphasizes basal-bolus and correctional insulin orders and excludes sliding scale, in conjunction with nursing personnel inservicing, improves outcomes.

Condition
Diabetes Mellitus

MedlinePlus related topics: Diabetes

Drug Information available for: Insulin

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Cross-Sectional
Official Title:	Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes

Further study details as provided by John H. Stroger Hospital:

Primary Outcome Measures:

Mean Inpatient Glucose [ Time Frame: Duration of Inpatient Stay ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Percentage of normoglycemic (70 to 150 mg/dl) patient-days [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Percentage of hyperglycemic patient-days [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Percentage of Patient-days with glucose less than 70 mg/dl [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: Yes ]
Percentage of Patients with inpatient or recent (less than 6 months) hemoglobin AIC [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Length of stay [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Distribution of oral hypoglycemic use [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Distribution of type of insulin therapy used [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: No ]
Percent of patient-days with severe hypoglycemia [ Time Frame: Duration of Inpatient stay ] [ Designated as safety issue: Yes ]

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	413
Study Start Date:	March 2006
Study Completion Date:	June 2008
Primary Completion Date:	December 2007 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Group admitted 1 (one) month before CPOE protocol changes were made
2 Group admitted 1 (one) year after CPOE protocol changes were made

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

Diabetic patients admitted to Medicine Services

Criteria

Inclusion Criteria:

Clinical diagnosis of Diabetes Mellitus

Exclusion Criteria:

Admitted to Non-Medicine Hospital Services

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00718198

Locations

United States, Illinois
John H. Stroger Jr. Hospital
Chicago, Illinois, United States, 60612

Sponsors and Collaborators

John H. Stroger Hospital

Investigators

Principal Investigator:	Yannis S Guerra, MD	Rush University Hospital/John H Stroger Jr. Hospital
Study Chair:	Krishna Das, MD	John H. Stroger Jr. Hospital
Study Chair:	Pete Antonopoulos, MD	John H. Stroger Jr. Hospital
Study Chair:	Irene Benson, RN	John H. Stroger Jr. Hospital
Study Chair:	Shane Borkowski, MD	John H. Stroger Jr. Hospital
Study Chair:	Leon Fogelfeld, MD	John H. Stroger Jr. Hospital
Study Chair:	Melanie Gordon, MD	John H. Stroger Jr. Hospital
Study Chair:	Betsy Palal, MD	John H. Stroger Jr. Hospital
Study Chair:	Joana Witsil, MD	John H. Stroger Jr. Hospital
Study Director:	Evelyn Lacuesta, MD	John H. Stroger Jr. Hospital

More Information

Responsible Party:	Rush University Hospital/John H. Stroger Jr. Hospital of Cook County ( Yannis Guerra )
Study ID Numbers:	JHSEndo01
Study First Received:	July 16, 2008
Last Updated:	July 16, 2008
ClinicalTrials.gov Identifier:	NCT00718198
Health Authority:	United States: Institutional Review Board

Keywords provided by John H. Stroger Hospital:

Inpatient
Computer Physician Order Entry
Diabetes Mellitus

Study placed in the following topic categories:

Metabolic Diseases
Diabetes Mellitus
Endocrine System Diseases
Endocrinopathy

Metabolic disorder
Glucose Metabolism Disorders
Insulin

ClinicalTrials.gov processed this record on January 13, 2009