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6th World Congress on Alternatives &
Animal Use in the Life Sciences
August 21-25, 2007
Tokyo, Japan

View Schedule of NICEATM/ICCVAM Presentations

Wednesday, Aug. 22

Session 9-2(1): Globalization: Validation and International Cooperation
10:15-12:15, Room 1-A

Title Fostering International Validation and Acceptance of New and Alternative Methods: ICCVAM and NICEATM Initiatives
Authors W Stokes, M Wind, L Schechtman, R Tice
Presenter William Stokes
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First Poster Session
13:30-15:30, Room 1-B

Title Topical Anesthetic Pre-treatment in the Draize Eye Test: Impact on Hazard Classification
Authors NY Choksi, JK Haseman, JF Truax, JM Charles, GR Wnorowski, DJ Merkel, WS Stokes
Presenter William Stokes
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Title The Redesigned NICEATM-ICCVAM Website: Improving Communication with Stakeholders
Authors D Winters, CS Sprankle, S Bailey, DG Allen, RR Tice, and WS Stokes
Presenter Raymond Tice
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Title Reducing Animal Use for Acute Oral Toxicity Testing: ICCVAM Recommendations for the Use of In Vitro Cytotoxicity Test Methods
Authors M Wind, A Rispin, R Tice, W Stokes
Presenter William Stokes
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Session 4-4: Methodology for the Validation Process of Alternative Assays
16:15-18:45, Room 3-G

Title Reference Chemicals: Issues and Challenges
Presenter Amy Rispin

Session 5-12: Comet Assay
Chairs: Raymond Tice and Brian Barlinson
16:15-18:45, Room 3-E

Title The Comet Assay: An Overview
Presenter Raymond Tice

Session 10-3: Linking Risk Assessment and Risk Management
16:15-18:45, Room 3-F

Title Risk Assessment Approach and Regulation
Presenter Marilyn Wind

Thursday, Aug. 23

Session 4-3: Regulatory Requirements for the Consideration of Alternatives
10:15-12:15, Room 1-A

Title U.S. Perspective on the “Consideration of Alternatives” Regulatory Requirement
Presenter Jodie Kulpa-Eddy

Session 5-1: Alternatives for Acute Systemic Toxicity
Chairs: Raymond Tice and Silvia Casati
13:00-15:00, Room 3-C

Title Alternatives for Acute Oral Systemic Toxicity Testing: NICEATM/ICCVAM Current and Planned Activities
Authors RR Tice, J Strickland, M Paris, M Wind, W Stokes
Presenter Raymond Tice
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Title The NICEATM/ECVAM Validation Study of In Vitro Cytotoxicity Test Methods for Estimating Rat Acute Oral Toxicity
Authors J Strickland, M Paris, S Casati, R Tice, W Stokes
Presenter Judy Strickland
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Session 5-2: Research, Development and Evaluation of Alternatives for Ocular Toxicity
Chairs: William Stokes and Odile deSilva
13:00-15:00, Room 3-F

Title Alternatives for Ocular Toxicity Testing: ICCVAM and NICEATM Recent and Planned Initiatives
Authors W Stokes, M Wind, N Choksi, D Allen, R Tice
Presenter William Stokes
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Session 7-2: Achievement in Other Biologicals Quality Control
Chairs: Richard McFarland and Toru Kawanishi
13:00-15:00, Room 3-J

Title 3Rs in Gene Therapies and Cellular Therapies in USA
Presenter Richard McFarland

Session 10-2: Assessment of Animal Health Risks and Animal Welfare Risks
13:00-15:00, Room 1-A

Title The Use of Alternative Methods in Public Health Practice Must Be Deliberative and Judicious
Presenter Moiz Mumtaz

Friday, Aug. 24

Session 2-4: Public Participation in Decision-Making on Animal Use in Different Cultural Contexts
Chairs: Margaret Snyder and Baroness Perry of Southwark
10:15-12:15, Room 3-E

Second Poster Session
15:30-17:30, Room 1-B

Title In Vitro Cytotoxicity Test Methods for Estimating Rat Acute Oral Toxicity: Prediction of GHS Acute Oral Toxicity Hazard Categories
Authors M Paris, J Strickland, S Casati, R Tice, W Stokes
Presenter William Stokes
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Title In Vitro Cytotoxicity Test Methods for Estimating Starting Doses for Rat Acute Oral Toxicity Tests: Impact on Animal Savings
Authors J Strickland, M Paris, S Casati, E Harvey, R Lee, W Jones, A Rispin, R Tice, W Stokes
Presenter Amy Rispin
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Title ICCVAM Recommendations for the Use of In Vitro Test Methods for the Identification and Classification of Ocular Corrosives and Severe Irritants
Authors KL Hamernik, JC Merrill, A Jacobs, D Lowther, M Wind, A Rispin, RR Tice, WS Stokes
Presenter Karen Hamernik
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Title Relationship Between Adverse Ocular Effects and Their Reversibility
Authors RR Tice, DG Allen, NY Choksi, JF Truax, WS Stokes
Presenter Raymond Tice
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Title ICCVAM Revised Recommended Substances for the Validation of In Vitro Estrogen Receptor and Androgen Receptor Binding and Transcriptional Activation Test Methods
Authors DG Hattan, ML Wind, P Ceger, FH Deal, RR Tice, WS Stokes
Presenter David Hattan
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Title Standardization of Protocols for the Validation of an In Vitro Estrogen Receptor Transcriptional Activation Assay
Authors RR Tice, FH Deal, P Ceger, GC Clark, JD Gordon, WS Stokes
Presenter Raymond Tice
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Title NICEATM/ECVAM/JaCVAM Multi-phased International Validation Study of an In Vitro Estrogen Receptor Transcriptional Activation Assay to Detect Agonist and Antagonist Activity
Authors WS Stokes, S Bremer, M Jacobs, A Ono, H Kojima, P Ceger, FH Deal, RR Tice
Presenter William Stokes
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Title Alternatives to the Mouse LD50 Assay For Botulinum Toxin Testing: An ICCVAM/NICEATM/ECVAM Sponsored Workshop
Authors JA Kulpa-Eddy, AC Jacobs, M Halder, TA Burns, NY Choksi, DG Allen, DW Winters, RR Tice, and WS Stokes
Presenter Jodie Kulpa-Eddy
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Title NICEATM and ICCVAM Evaluation of Five In Vitro Test Methods for Assessing Potential Pyrogenicity of Pharmaceuticals and Other Products
Authors RD McFarland, EA Lipscomb, DG Allen, JF Truax, RR Tice, and WS Stokes
Presenter Richard McFarland
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Title Evaluation Of Potential False Negative Corrosive Chemicals in Proposed In Vitro Dermal Irritation Assays
Authors DG Allen, J Truax, A Rispin, A Jacobs, K Hamernik, RR Tice, WS Stokes
Presenter W. Stokes
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Saturday, Aug. 25

Session 2-2(2): Impacts of Policy Implementation on Trends in Animal Use and Science
10:15-12:15, Room 3-G

Title A Review of Trends in Animal Use in the United States
Presenter Jodie Kulpa-Eddy

Session 5-10: Validation
10:15-12:15, Room 3-C

Title The ICCVAM Process for Validation and Evaluation of New and Alternative Methods
Authors M Wind and W Stokes
Presenter Marilyn Wind
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