NICEATM 5th World Congress Presentations and Posters



ICCVAM-NICEATM Workshop Lectures and Poster Presentations at the 5^th World Congress on Alternatives and Animal Use in the Life Sciences August 21-25, 2005 Berlin, Germany Return to NICEATM/ICCVAM Home Page Adobe Acrobat Reader Required to View Posters and Abstracts Download Adobe Acrobat Reader SATELLITE CONFERENCE 2nd International Conference on the Use of Humane Endpoints in Animal Experiments for Biomedical Research Saturday-Sunday, August 20-21, 2005 Organized by the Paul-Ehrlich-Institut (PEI); the Netherlands Vaccin Institute (NVI), and the University of Birmingham (UK) Federal Institute for Risk Assessment, Berlin http://www.humane-endpoints.org/ Humane Endpoints for Animals Used in Biomedical Research and Testing: Best Practices, Policies, and Progress in the United States. Stokes WS. WORKSHOP LECTURES 5th World Congress Program Page Click on presentation title to view abstract. Monday, August 22, 2005 5.11 Workshop: Mechanisms of Chemically-induced Ocular Injury and Recovery: Current Understanding and Research Needs 11.30-13.30 h ECC Hall D Mechanisms of chemically-induced ocular injury and recovery: Current understanding and knowledge gaps Stokes WS, NY Choksi, DG Allen, JF Truax, RR Tice, C Eskes, M Wind, LM Schechtman, K Hamernik In vitro models for ocular injury: Current and potential biomarkers C Eskes, DG Allen, RR Tice, NY Choksi, JF Truax, W Chambers, Stokes WS, LM Schechtman 3.2 Workshop: Establishing the 3Rs Principle around the World 15.00-17.00 h Estrel Hall A NIEHS: Program in alternative test method research, development and validation JJ Heindel, WS Stokes, C Portier 5.1 Session: Strategies for Using Non-animal Methods in Relation to HPV, Endocrine Disruptors, and REACH Legislation 15.00-17.00 h ECC Hall D ICCVAM's role in validating in vitro test methods for endocrine disruptor screening M Wind, BC Blackard, RR Tice, WS Stokes, LM Schechtman Tuesday, August 23, 2005 3.3 Workshop: Forum of National and International Institutions Funding 10.00-12.00 h Estrel Hall A Research directions in toxicology at the US National Toxicology Program C Portier, J Bucher, WS Stokes, M Wolfe *5.6 Session: In Vitro* Aproaches for Determining Acute Systemic Toxicity** 10.00-12.00 h Estrel Hall C5/C6 Analysis of the correlation between in vitro cytotoxicity data and acute toxic effects in humans S Casati, S Hoffmann, JA Strickland, MW Paris, WS Stokes, RR Tice, I Malerba *5.7 Session: In Vitro* Aproaches for Determining Acute Systemic Toxicity 14.00-16.00 h Estrel Hall C5/C6 The Importance of Good Cell Culture Practice (GCCP) M Balls, S Coecke, G Bowe, J Davis, G Gstraunthaler, T Hartung, R Hay, O-W Merten, A Price, LM Schechtman, G Stacey, WS Stokes Standardization in Cell and Tissue Culture - The Need for Specific GLP Guidelines in the Cell Culture Laboratory (Good Cell Culture Practice - GCCP) G Gstraunthaler, S Coecke, M Balls, G Bowe, J Davis, T Hartung, R Hay, O-W Merten, A Price, WS Stokes, LM Schechtman, G Stacey 5.14 Workshop: Meeting the Challenge of the 7th Amendment to the EU Cosmetics Directive 14.00-16.00 h ECC Hall D Sound Science: A prerequisite for advancing alternative methods and protecting public health WS Stokes Wednesday, August 24, 2005 5.5 Session: Advancements and Needs for Developing and Validating Alternatives for Ocular Irritancy and Corrosivity Testing** 14.00-16.00 h ECC Hall D ICCVAM progress in evaluating in vitro test methods for identifying severe ocular irritants/corrosives J Merrill, K Hamernik, WS Stokes, LM Schechtman, M Wind Minimizing pain and distress in ocular safety testing: Current best practices and research needs WS Stokes, K Gupta, D Lowther, W Chambers, M Wind, M Snyder, A Jacobs, R Bronaugh, DG Allen, RR Tice, J Merrill, LM Schechtman 5.13 Workshop: Strategies for Priorotizing and Streamlining the Validation Process 14.00-16.00 h Estrel Hall A The ICCVAM nomination and submission process and guidelines for new, revised, and alternative test methods LM Schechtman, ML Wind, WS Stokes The use of test method performance standards to streamline the validation process WS Stokes, LM Schechtman, ML Wind, A Rispin, K Gupta, RR Tice POSTER PRESENTATIONS Tuesday, August 23, 2005 [5th World Congress Program Page] 13.00-14.00 h Click on presentation title to view abstract. 5.1 Session: Strategies for Using Non-animal Methods in Relation to HPV, Endocrine Disruptors, and REACH Legislation. P088 ICCVAM recommended reference chemicals for validation of in vitro estrogen and androgen receptor binding and transcriptional activation assays Blackard BC, CJ Inhof, RR Tice, WS Stokes, M Wind, D Hattan, LM Schechtman View Poster. 5.5 Session: Advancements and Needs for Developing and Validating Alternatives for Ocular Irritancy and Corrosivity Testing. P156 Performance of the Bovine Corneal Opacity and Permeability (BCOP) test method in detecting ocular corrosives and severe irritants Tice RR, DG Allen, BC Blackard, NY Choksi, CJ Inhof, JF Truax, WS Stokes View Poster. P157 Performance of the Isolated Rabbit Eye (IRE) test method in detecting ocular corrosives and severe irritants Truax JF, DG Allen, BC Blackard, NY Choksi, CJ Inhof, RR Tice, WS Stokes View Poster. P158 Performance of the Isolated Chicken Eye (ICE) test method in detecting ocular corrosives and severe irritants Allen DG, BC Blackard, NY Choksi, CJ Inhof, JF Truax, RR Tice, WS Stokes View Poster. P159 Performance of the Hen's Egg Test - Chorioallantoic Membrane (HET-CAM) test method in detecting ocular corrosives and severe irritants Choksi NY, DG Allen, BC Blackard, CJ Inhof, RR Tice, JF Truax, WS Stokes View Poster. P160 Proposed reference substances for optimization and validation studies with in vitro ocular test methods Allen DG, BC Blackard, NY Choksi, JF Truax, RR Tice, WS Stokes, K Hamernik, J Merrill, L Schechtman, M Wind View Poster. P161 Estimated under- and over-classification rates for a 1-3 rabbit sequential Draize rabbit eye test Haseman J, RR Tice, DG Allen, NY Choksi, WS Stokes View Poster. *5.6 Session: In Vitro* Aproaches for Determining Acute Systemic Toxicity.** P181 Protocol optimization during a validation study to evaluate in vitro cytotoxicity assays for estimating rodent acute systemic toxicity Paris MW, JA Strickland, WS Stokes, S Casati, RR Tice, H Raabe, C Cao, R Clothier, J Harbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, J Haseman, P Crockett, M Wenk, M Vallant View Poster. P185 Results of the final phase of a validation study to evaluate in vitro cytotoxicity assays for estimating rodent acute systemic toxicity Stokes WS, MW Paris, JA Strickland, S Casati, RR Tice, H Raabe, C Cao, R Clothier, JHarbell, G Mun, A Sizemore, G Moyer, J Madren-Whalley, C Krishna, M Owen, N Bourne, J Haseman, P Crockett, E Harvey, R Lee, M Wenk, M Vallant View Poster. P186 Data collection and analysis for an in vitro cytotoxicity validation study Strickland JA, MW Paris, H Raabe, J Haseman, S Casati, R Clothier, C Cao, P Crockett, RR Tice, WS Stokes View Poster.

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