Mosaic Vaccine Designer

Purpose: The Mosaic Vaccine Designer will generate candidate vaccine protein cocktails that optimize the coverage, by a small set of mosaic proteins that could be included in a vaccine cocktail, of potential T-cell epitopes in a large diverse set of proteins.

The Mosaic Explanation page provides additional information to get you started. Please read it before using this tool.

Usage: Paste your protein sequences in the box, or upload a file containing sequences. Input sequences do not need to be aligned. When your job is completed, a link to your results will be sent to the e-mail address you provide.
Your job may take several hours or even days, depending on your input.

Download stand-alone Mosaic Vaccine Designer

• Mosaic Vaccine Designer source code and documentation

Related Programs

• Epitope Coverage Assessment Tool: Epicover
• Positional Epitope Coverage Assessment Tool: Posicover

Contributors

• Hyejin Yoon - web implementation and perl programming (at lanl.gov, email address 'hyoon'),
• Will Fischer - perl programming (at lanl.gov, email address 'wfischer'),
• Simon Perkins - original algorithm and C programming (at ultraspectral.com, email address 'simon.perkins')

References

• Vaccine design paper (Fischer et al. 2007): Nature abstract or PubMed abstract
• Tool description paper (Thurmond et al. 2008): Bioinformatics abstract or PubMed abstract