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National Center for Research Resources, National Institutes of Health. Providing clinical and translational researchers with the training and tools they need to transform basic discoveries into improved human health.

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NCRR's Division for Clinical Research Resources provides funding to biomedical research institutions to establish and maintain specialized clinical research facilities and clinical-grade biomaterials that enable clinical and patient-oriented research.

NCRR's Division of Comparative Medicine helps meet the needs of biomedical researchers for high-quality, disease-free animals and specialized animal research facilities.

NCRR's Division of Research Infrastructure supports programs to enhance the competitiveness of investigators in underserved states and institutions and also provides funding to build, expand, remodel, or renovate research facilities throughout the nation.

NCRR's Science Education Partnership Awards are designed to improve life science literacy throughout the nation.

NCRR's Division of Biomedical Technology supports research to develop innovative technologies and helps make them accessible to the biomedical research community.

Funding Programs

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Funding Category

Program Description

Mechanism

NCRR Contacts

Research Grants

Academic Research Enhancement Awards (AREA):
Supports small-scale, resource-related research projects conducted by faculty at institutions that award bachelor degrees in health or the health sciences. Areas of interest to NCRR include research and development of instruments/technologies, laboratory animal sciences, or lower organisms, tissues, and cells in culture for use in biomedical research.

R15

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Facilities Improvement

Animal Facilities Improvement:
Supports upgrades to animal facilities for the conduct of biomedical and behavioral research funded by the U.S. Public Health Service and assists institutions to comply with the Animal Welfare Act and other Federal requirements related to the care and use of laboratory animals.

G20

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Resources and Centers

Animal Model, Animal, and Biological Materials Resources:
Supports specialized colonies of laboratory animals, including nonhuman primates; biological materials; genetic stocks, and animal-related information resources. These resources serve qualified investigators without regard to scientific disciplines or disease orientations of research activities.

P40

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Resources and Centers

Animal Model, Animal, and Biological Materials Resources (Cooperative Agreement):
Supports development of mammalian and non-mammalian models for all qualified investigators without regard to the scientific disciplines or disease orientations of their research activities.

U42

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Resources and Centers

Biomedical Technology Resource Centers:
Supports centers and core staff who conduct research to discover, create, develop, and disseminate innovative techniques and technologies for a broad spectrum of research activities. Centers are accessible to qualified investigators supported by NIH and other peer-reviewed research project grants.

P41

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Resources and Centers

Clinical and Translational Science Awards:
Provides support to institutions to create a dependable academic home that will speed medical discoveries into improved patient care. Encourages the development of novel methods and approaches to clinical and translational research, enhances informatics and technology resources, and improves training and mentoring to recruit and retain clinical and translational researchers. To create this home, the program allows for local flexibility so that each institution can determine whether to establish a Center, Department, or Institute (C/D/I) in clinical and translational science.

KL2, TL1, UL1

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Research Career Development and Training Awards

Clinical Research Curriculum Award (CRCA):
Provides clinical investigators—through an institutional award—with opportunities to receive high quality, multidisciplinary didactic training as part of their career development.

K30

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Research Grants

Exploratory/Developmental Research Projects - Phase I:
Supports innovative, high-risk, exploratory/development projects for new or improved biomedical technologies or animal or animal-related models for biomedical research applications. Preliminary data are not required. Projects should challenge paradigms and encompass existing novel ideas to improve the understanding of a biomedical research problem.

R21

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Resources and Centers

General Clinical Research Centers:
Supports specialized clinical research facilities, including core research staff, for multidisciplinary inpatient and outpatient studies. Centers, typically located at medical schools and other research institutions, are accessible to qualified investigators supported by NIH and other peer-reviewed research project grants.

M01

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Resources and Centers

Institutional Development Award:
Supports health-related research at institutions in states with historically low aggregate success rates for receiving competitive NIH grant awards. Such support enhances the competitiveness of investigators at eligible institutions and helps broaden the geographic distribution of NIH funding.

P20

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Research Grants

Investigator-Initiated Research Project:
Supports a discrete specified project performed in an investigator's area of competency. Areas of interest to NCRR include research to create new or to improve existing technologies or instruments or to establish, expand, or improve an animal model or model system.

R01

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

Mentored Clinical Research Scholar (CRS) Award:
Provides support to educational institutions to establish programs that will develop the research skills of physicians and dentists so that these professionals may become independent clinical investigators.

K12

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Research Career Development and Training Awards

Mentored Patient-Oriented Research Career Development Award:
Supports clinically trained physicians and dentists to develop clinical research skills required to gain experience in advanced clinical research methods and experimental approaches.

K23

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Research Career Development and Training Awards

Midcareer Investigator Award in Mouse Pathobiology Research:
Supports established pathobiologists to allow them protected time to devote to mouse pathobiology research and to mentor new investigators.

K26

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

Midcareer Investigator Award in Patient-Oriented Research:
Supports clinicians to allow them protected time to devote to clinical/patient-oriented research, enhance clinical research skills, and mentor beginning clinical investigators.

K24

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Resources and Centers

National Primate Research Centers:
Supports specialized nonhuman primate (NHP) research facilities, including core research staff, equipment, NHP breeding colonies, and related resources. These centers are accessible to qualified investigators supported by NIH and other peer-reviewed research project grants.

P51

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

National Research Service Award - Individual Postdoctoral Fellowship:
Provides postdoctoral research training to individuals to broaden their scientific background and potential for research in specified health areas.

F32

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

National Research Service Award - Individual Predoctoral Fellowship:
Provides predoctoral students with supervised research training in specified health and health-related areas leading toward the research degree.

F31

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

National Research Service Award - Institutional Training:
Enables institutions to award NRSAs to persons selected by them for predoctoral and postdoctoral research training in specified shortage areas.

T32

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

National Research Service Award - Professional Student Short-Term Research Training:
Supports institutions to provide veterinary students in health professional schools research experience for periods of two to three months—during quarters or summer periods—to encourage research in areas of national need.

T35

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

National Research Service Award - Senior Fellows:
Provides support to allow for protected time for training scientists who have at least 7 years of research experience and wish to significantly change the direction of their research careers, or to broaden their scientific background by acquiring new research capabilities. An award may be used in conjunction with sabbatical leave.

F33

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Career Development and Training Awards

NIH Pathway to Independence (PI) Award:
Provides opportunities for promising postdoctoral scientists to receive both mentored and independent research support from the same award. The initial phase will provide 1–2 years of mentored support for highly promising, postdoctoral research scientists, followed by up to 3 years of independent support contingent on securing an independent research position. Award recipients will be expected to compete successfully for independent R01 support from the NIH during the career transition award period.

K99, R00

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Resources and Centers

Research Centers in Minority Institutions (RCMI):
Supports research infrastructure at institutions that have more than 50 percent enrollment of under-represented minority students and that offer doctoral degrees in health professions and health-related sciences. Infrastructure support includes laboratory and animal facility renovations, faculty recruitment, pilot research projects, equipment acquisition, and more.

G12

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Resources and Centers

Research Centers in Minority Institutions Clinical Research Infrastructure Initiative (RCRII):
Supports RCMI-eligible institutions affiliated with medical schools to establish independent clinical research centers.

P20

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Facilities Improvement

Research Facilities Improvement:
Supports expansion, remodeling, renovation, or alteration of existing research facilities or construction of new research facilities. Facilities must support basic or clinical biomedical or behavioral research or research training.

C06

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Research Grants

Resource-Related Grant:
Supports applied studies to characterize and develop new animal, cell culture, or computer/mathematics models (or to improve existing ones) that have the potential for becoming well-used systems for research projects. Applicants must demonstrate a need for the resource within the biomedical research community.

R24

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Resources and Centers

Resource-Related Research Projects:
Supports research projects that contribute to improvement of resources capability to serve biomedical research.

U24

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Grants

Science Education Partnership Award:
Supports partnerships among biomedical and behavioral researchers, educators, community groups, and other organizations to create and disseminate science education programs that provide students, teachers, and the general public with a better understanding of life sciences. Programs are also designed to encourage students to pursue higher science education and scientific careers.

R25

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Research Grants

Scientific Conferences:
Supports grantee-sponsored and directed international and national meetings, conferences, and workshops related to research resources.

R13, U13

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Shared Instrumentation

Shared Instrumentation Grants:
Supports the purchase of commercially available and technologically sophisticated instruments in the $100,000 to $500,000 price range. Instruments must be used on a shared basis at institutions with a high concentration of investigators supported by NIH research project grants.

S10

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Shared Instrumentation

Shared Instrumentation, High-End Grants:
Supports the acquisition of a major, advanced instrument in the $750,000 to $2,000,000 range (direct costs only). The instrument must be used on a shared basis at institutions with a high concentration of investigators supported by NIH research project grants.

S10

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Small Business Award Programs

Small Business Innovation Research Awards (SBIR):
Phase I (R43) supports research to establish the technical merit and feasibility of research ideas that may ultimately lead to commercial products or services that will have broad application to biomedical research. Phase I also determines the quality of performance of the small business awardee organization prior to providing further federal support.

R43

Dr. Amy Swain, Health Scientist Administrator
301-435-0752
swaina@mail.nih.gov

Small Business Award Programs

Small Business Innovation Research Awards (SBIR):
Phase II (R44) supports research or research and development (R&D) initiated in Phase I that is likely to result in commercial products or services.

R44

Dr. Amy Swain, Health Scientist Administrator
301-435-0752
swaina@mail.nih.gov

Small Business Award Programs

Small Business Technology Transfer Program (STTR):
Phase I (R41) and Phase II (R42) of the STTR Program seek to increase the commercialization of technology developed through Federal funding that will ultimately benefit the public. However, the unique feature of the STTR Program is the requirement for the small business concern applicant organization to partner and formally collaborate with research universities and other nonprofit research institutions. Important differences between the SBIR and STTR program requirements are explained on the NIH SBIR and STTR Web site.

R41, R42

Dr. Amy Swain, Health Scientist Administrator
301-435-0752
swaina@mail.nih.gov

Research Career Development and Training Awards

Special Emphasis Research Career Award in Pathology and Comparative Medicine:
Supports graduate veterinarians with experience in laboratory animal sciences to become independent biomedical investigators in research that is related to comparative medicine.

K01

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Resources and Centers

Specialized Center (Cooperative Agreement):
Supports any part of the full range of research and development where the spectrum of activities comprises a multi-disciplinary approach on a specific disease or biomedical problem area.

U54

Biomedical Technology
301-435-0755
BTADIR@ncrr.nih.gov

Clinical Research
301-435-0790
CRADIR@ncrr.nih.gov

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

Research Infrastructure
301-435-0788
RIADIR@ncrr.nih.gov

Research Career Development and Training Awards

Training for Veterinary Students in Animal-Oriented, Hypothesis-Based Research - Institutional Training:
Enables institutions to award grants to support individuals pursuing a degree in veterinary medicine (D.V.M. or V.M.D.) for a one-year training opportunity in hypothesis-based laboratory animal medicine, comparative medicine or pathology, or related areas in biomedical research.

T32

Comparative Medicine
301-435-0744
CMADIR@ncrr.nih.gov

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