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Volume 17(1);  January 2008
Editorial
Changes at Protein Science
Brian W. Matthews
Protein Sci. 2008 January; 17(1): 1.
PMCID: PMC2144587
Review
Amyloid—a state in many guises: Survival of the fittest fibril fold
Jesper S. Pedersen and Daniel E. Otzen
Protein Sci. 2008 January; 17(1): 2–10. doi: 10.1110/ps.073127808.
PMCID: PMC2144592
Accelerated Communication
Energetic rationale for an unexpected and abrupt reversal of guanidinium chloride-induced unfolding of peptide deformylase
Alexander K. Berg, Sumathra Manokaran, Daniel Eiler, Joel Kooren, Sanku Mallik, and D.K. Srivastava
Protein Sci. 2008 January; 17(1): 11–15. doi: 10.1110/ps.073270608.
PMCID: PMC2144594
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5
Lidia Mosyak, Katy Georgiadis, Tania Shane, Kristine Svenson, Tracy Hebert, Thomas McDonagh, Stewart Mackie, Stephane Olland, Laura Lin, Xiaotian Zhong, Ronald Kriz, Erica L. Reifenberg, Lisa A. Collins-Racie, Christopher Corcoran, Bethany Freeman, Richard Zollner, Tod Marvell, Matthew Vera, Phaik-Eng Sum, Edward R. Lavallie, Mark Stahl, and William Somers
Protein Sci. 2008 January; 17(1): 16–21. doi: 10.1110/ps.073287008.
PMCID: PMC2144589
Articles
Functional flexibility of human cyclin-dependent kinase-2 and its evolutionary conservation
Iveta Bártová, Jaroslav Koča, and Michal Otyepka
Protein Sci. 2008 January; 17(1): 22–33. doi: 10.1110/ps.072951208.
PMCID: PMC2144583
DNA inhibits catalysis by the carboxyltransferase subunit of acetyl-CoA carboxylase: Implications for active site communication
Brian K. Benson, Glen Meades, Jr, Anne Grove, and Grover L. Waldrop
Protein Sci. 2008 January; 17(1): 34–42. doi: 10.1110/ps.073186408.
PMCID: PMC2144591
Folding thermodynamics and kinetics of the leucine-rich repeat domain of the virulence factor Internalin B
Naomi Courtemanche and Doug Barrick
Protein Sci. 2008 January; 17(1): 43–53. doi: 10.1110/ps.073166608.
PMCID: PMC2144584
Robust recognition of zinc binding sites in proteins
Jessica C. Ebert and Russ B. Altman
Protein Sci. 2008 January; 17(1): 54–65. doi: 10.1110/ps.073138508.
PMCID: PMC2144590
Characterization of an exosite binding inhibitor of matrix metalloproteinase 13
Lata T. Gooljarsingh, Ami Lakdawala, Frank Coppo, Lusong Luo, Gregg B. Fields, Peter J. Tummino, and Richard R. Gontarek
Protein Sci. 2008 January; 17(1): 66–71. doi: 10.1110/ps.073130208.
PMCID: PMC2144595
Identification of transient hub proteins and the possible structural basis for their multiple interactions
Miho Higurashi, Takashi Ishida, and Kengo Kinoshita
Protein Sci. 2008 January; 17(1): 72–78. doi: 10.1110/ps.073196308.
PMCID: PMC2144588
Modeling of protein binary complexes using structural mass spectrometry data
J.K. Amisha Kamal and Mark R. Chance
Protein Sci. 2008 January; 17(1): 79–94. doi: 10.1110/ps.073071808.
PMCID: PMC2144602
Contributions of a disulfide bond to the structure, stability, and dimerization of human IgG1 antibody CH3 domain
Arnold McAuley, Jaby Jacob, Carl G. Kolvenbach, Kimberly Westland, Hyo Jin Lee, Stephen R. Brych, Douglas Rehder, Gerd R. Kleemann, David N. Brems, and Masazumi Matsumura
Protein Sci. 2008 January; 17(1): 95–106. doi: 10.1110/ps.073134408.
PMCID: PMC2144599
Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins
Cyril Pimentel, Sarrah M'Barek, Violetta Visan, Stephan Grissmer, François Sampieri, Jean-Marc Sabatier, Hervé Darbon, and Ziad Fajloun
Protein Sci. 2008 January; 17(1): 107–118. doi: 10.1110/ps.073122908.
PMCID: PMC2144586
The yeast Ski complex is a hetero-tetramer
Silvia A. Synowsky and Albert J.R. Heck
Protein Sci. 2008 January; 17(1): 119–125. doi: 10.1110/ps.073155908.
PMCID: PMC2144600
Crystal structure of 5-methylthioribose 1-phosphate isomerase product complex from Bacillus subtilis: Implications for catalytic mechanism
Haruka Tamura, Yohtaro Saito, Hiroki Ashida, Tsuyoshi Inoue, Yasushi Kai, Akiho Yokota, and Hiroyoshi Matsumura
Protein Sci. 2008 January; 17(1): 126–135. doi: 10.1110/ps.073169008.
PMCID: PMC2144596
Crystal structure of an archaeal Ski2p-like protein from Pyrococcus horikoshii OT3
Xiaodong Zhang, Takashi Nakashima, Yoshimitsu Kakuta, Min Yao, Isao Tanaka, and Makoto Kimura
Protein Sci. 2008 January; 17(1): 136–145. doi: 10.1110/ps.073107008.
PMCID: PMC2144603
Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite
Robson Q. Monteiro, Alireza R. Rezaie, Jong-Sup Bae, Eric Calvo, John F. Andersen, and Ivo M.B. Francischetti
Protein Sci. 2008 January; 17(1): 146–153. doi: 10.1110/ps.073016308.
PMCID: PMC2144593
Protein Structure Reports
The hypothetical protein Atu4866 from Agrobacterium tumefaciens adopts a streptavidin-like fold
Xuanjun Ai, Anthony Semesi, Adelinda Yee, Cheryl H. Arrowsmith, Wing-Yiu Choy, and Shawn S.C. Li
Protein Sci. 2008 January; 17(1): 154–158. doi: 10.1110/ps.073167408.
PMCID: PMC2144585
Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response
Manchi C.M. Reddy, Kuppan Gokulan, William R. Jacobs, Jr, Thomas R. Ioerger, and James C. Sacchettini
Protein Sci. 2008 January; 17(1): 159–170. doi: 10.1110/ps.073192208.
PMCID: PMC2144582
For the Record
Solution NMR studies of apo-mSin3A and -mSin3B reveal that the PAH1 and PAH2 domains are structurally independent
Yuan He and Ishwar Radhakrishnan
Protein Sci. 2008 January; 17(1): 171–175. doi: 10.1110/ps.073097308.
PMCID: PMC2144601
Selenoproteinless animals: Selenophosphate synthetase SPS1 functions in a pathway unrelated to selenocysteine biosynthesis
Alexey V. Lobanov, Dolph L. Hatfield, and Vadim N. Gladyshev
Protein Sci. 2008 January; 17(1): 176–182. doi: 10.1110/ps.073261508.
PMCID: PMC2144598
Protein folding transition states probed by loop extension
Ignacio Enrique Sánchez
Protein Sci. 2008 January; 17(1): 183–186. doi: 10.1110/ps.073217708.
PMCID: PMC2144597
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