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Chloroquine treatment, followed by weekly chloroquine
prophylaxis and then, after delivery, treatment
with primaquine is the appropriate course of treatment.
Primaquine is contraindicated during pregnancy, thus radical
treatment (to eliminate dormant liver stages) must be delayed
until after delivery (and after a normal G6PD test!). During
the rest of the pregnancy, protection against clinical relapses
is achieved through weekly chloroquine prophylaxis. Plasmodium
vivax from Guatemala is unlikely to be chloroquine-resistant
and thus treatment with quinine plus doxycycline is not required.
(In addition, doxycycline is contraindicated in pregnant
women!)
Page last modified : May 21, 2004
Content source: Division of Parasitic Diseases
National Center for Zoonotic, Vector-Borne, and Enteric Diseases (ZVED)
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