Centers for Disease Control and Prevention Centers for Disease Control and Prevention CDC Home Search CDC CDC Health Topics A-Z site search
National Office of Public Health Genomics
Centers for Disease Control and Prevention
Office of Genomics and Disease Prevention
Site Search

HuGENet Publications
Assessment of cumulative evidence on genetic associations: interim guidelines
John PA Ioannidis1–3,*, Paolo Boffetta4, Julian Little5, Thomas R O’Brien6, Andre G Uitterlinden7, Paolo Vineis8, David J Balding8 Anand Chokkalingam9, Siobhan M Dolan10, W Dana Flanders11, Julian PT Higgins12, Mark I McCarthy13,14, David H McDermott15, Grier P Page16, Timothy R Rebbeck174, Daniela Seminara18 and Muin J Khoury19
International Journal of Epidemiology 2008; 37(1):120-132
line

FIGURE 1: Categories for the credibility of cumulative epidemiological evidence. The three letters correspond (in order) to amount of evidence, replication and protection from bias. Evidence is categorized as strong, when there is A for all three items, and is categorized as weak when there is a C for any of the three items. All other combinations are categorized as moderate

figure 1

<< back to publication

 
Page last reviewed: March 20, 2008 (archived document)
Content Source: National Office of Public Health Genomics