CDC's National Office of Public Health Genomics seeks a new behavioral health scientist. For more information about the position, visit the U.S. Department of Health and Human Services web site and enter the vacancy number (HHS-CDC-T2-2008-0766 — for current employees or HHS-CDC-D2-2008-0312 — for non-federal applicants). The deadline to apply is September 23, 2008.
	New National Cancer Institute Public Health Genomics Web site. Learn about public health genomics funding opportunities, training, seminars, and more.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Cancer
New approach to detect rare genetic variants aims to help women evaluate hormone replacement therapy and breast cancer risk, Medical News Today, September 18	Significant benefits in non-small-cell lung cancer from customizing erlotinib treatment, News-Medical.Net, September 15
'1-hit' event provides new opportunity for colon cancer prevention, say Fox Chase researchers, EurekAlert, September 15	Variations in cyclin D1 gene increase susceptibility to malignant melanoma, News-Medical.Net, September 15
Identification of cancer-causing gene in many colon cancers, Medical News Today, September 15	Scientists discover common variants in the human genome..., News-Medical.Net, September 14
Scientists identify ependymoma genes, News-Medical.Net, September 15	Risk of breast cancer mutations..., News-Medical.Net, September 11

Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer Boccia S, et al. Cancer Lett 2008 Sep

Candidate gene polymorphisms and the 9p21 locus in acute coronary syndromes
Tousoulis D, et al.
Trends Mol Med 2008 Sep

Genetics and genome-wide association studies: surgery-guided algorithm and promise for future breast cancer personalized surgery
Roukos DH
Expert Rev Mol Diagn 2008 Sep;8(5):587-97

Genes, environment, and interactions in prevention of type 2 diabetes: a focus on physical activity and lifestyle changes
Qi L, et al.
Curr Mol Med 2008 Sep;8(6):519-32

Identifying modifier genes of monogenic disease: strategies and difficulties
Genin E, et al.
Hum Genet 2008 Sep

Power, Validity, Bias and Robustness of Family-based Association Analysis Methods in the Presence of Linkage for Late Onset Diseases
Nsengimana J & Barrett JH
Ann Hum Genet 2008 Sep

Genetic susceptibility to autoimmune disorders: clues from gene association and gene expression studies
Gutierrez-Roelens I & Lauwerys BR
Curr Mol Med 2008 Sep;8(6):551-61

Estimating the Single Nucleotide Polymorphism Genotype Misclassification From Routine Double Measurements in a Large Epidemiologic Sample
Heid IM, et al.
Am J Epidemiol 2008 Sep

Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions
van Os J, et al.
Schizophr Bull 2008 Sep

Preterm birth and inflammation-The role of genetic polymorphisms
Holst D & Garnier Y
Eur J Obstet Gynecol Reprod Biol 2008 Sep

The genetics of type 2 diabetes: a realistic appraisal circa 2008
Florez JC
J Clin Endocrinol Metab 2008 Sep

Validity of a self-reported measure of familial history of obesity
Paradis AM, et al.
Nutr J 2008 Sep;7(1):27

A Pilot Study of a Family History Risk Assessment Tool for Cardiovascular Disease
Macleod HM & McNally EM
J Genet Couns 2008 Sep

 

The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV
Schackman BR, et al.
AIDS 2008 Oct;22(15):2025-33

The Trajectory of Psychological Impact in BRCA1/2 Genetic Testing: Does Time Heal?
Beran TM, et al.
Ann Behav Med 2008 Sep

What Patients and Their Relatives Think About Testing for BMPR2
Jones DL, et al.
J Genet Couns 2008 Sep

Decreasing uptake of predictive testing for Huntington's disease in a German centre: 12 years' experience (1993-2004)
Bernhardt C, et al.
Eur J Hum Genet 2008 Sep

Familial Aggregation of Common Sequence Variants on 15q24-25.1 in Lung Cancer
Liu P, et al.
J Natl Cancer Inst 2008 Sep

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending September 17, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Certain Conditions Originating in the Perinatal Period
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page