CDC's National Office of Public Health Genomics seeks a new health scientist. For more information about this position, click on the U.S. Department of Health and Human Services website and enter the vacancy number. The deadline to apply is March 12, 2008. CDC Employees: Use HHS-CDC-T2-2008-0382 if you are a current employee. If you are a current employee who is also a medical officer, please use HHS-CDC-T1-2008-0009. Non-CDC: Use HHS-CDC-D2-2008-0136 if you are a non-federal applicant. If you are a non-federal applicant who is also a medical doctor (MD), please use HHS-CDC-D1-2008-0007.
	New article “Cracking the Code, Integrating Asthma Genomics into Public Health” published in the March/April issue of Advance newsletter for Managers of Respiratory Care. See quotes by Dr. Muin J. Khoury and other experts.
	The National Institutes of Health (NIH) is hosting a meeting on "Translating Whole Genome Association Data into Clinical Research and Practice", March 10-11, 2008 in Bethesda, MD as part the NIH Genes, Environment, and Health Initiative.
	CDC is sponsoring an ASHG Genetics and Public Health Research and Practice Program fellowship to enhance CDC’s current activities and develop new approaches in integrating genetics and genomics into public health policy and programs at the national, state, and local levels. The deadline to apply is March 15, 2008.
	NIH's National Human Genome Research Institute is sponsoring a grant for Centers of Excellence in Genomics Science to advance genome research. For more information, visit the NIH web site.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

catmap: Case-control And TDT Meta-Analysis Package
Nicodemus KK
BMC Bioinformatics 2008 Feb;9(1):130

Recent advances in the genetics of phaeochromocytoma and functional paraganglioma
Gimenez-Roqueplo AP, et al.
Clin Exp Pharmacol Physiol 2008 Apr;35(4):376-9

Clinical consequences of ADRbeta2 polymorphisms
Hawkins GA, et al.
Pharmacogenomics 2008 Mar;9(3):349-58

Pharmacogenomics of anti-TB drugs-related hepatotoxicity
Roy PD, et al.
Pharmacogenomics 2008 Mar;9(3):311-21

Selection of Influential Genetic Markers Among a Large Number of Candidates Based on Effect Estimation Rather than Hypothesis Testing: An Approach for Genome-Wide  Association Studies
Stromberg U, et al.
Epidemiology 2008 Feb

Discovering susceptibility genes for asthma and allergy
Vercelli D
Nat Rev Immunol 2008 Mar;8(3):169-82

Genome-wide approaches to identify pharmacogenetic contributions to adverse drug  reactions
Nelson MR, et al.
Pharmacogenomics J 2008 Feb

Susceptibility loci involved in cisplatin-induced cytotoxicity and apoptosis
Shukla SJ, et al.
Pharmacogenet Genomics 2008 Mar;18(3):253-62

A simulated genetic structure for bipolar illness
Nurnberger JI Jr
Am J Med Genet B Neuropsychiatr Genet 2008 Mar

Asthma from a pharmacogenomic point of view
Szalai C, et al.
Br J Pharmacol 2008 Mar

Bias-reduced estimators and confidence intervals for odds ratios in genome-wide association studies Zhong H & Prentice RL
Biostatistics 2008 Feb

 

Health Behavior Changes After Genetic Risk Assessment for Alzheimer Disease: The  REVEAL Study
Chao S, et al.
Alzheimer Dis Assoc Disord 2008 Jan-2008 Mar;22(1):94-7

Ethical, legal, and social concerns about expanded newborn screening: fragile X syndrome as a prototype for emerging issues
Bailey DB Jr, et al.
Pediatrics 2008 Mar;121(3):e693-704

A systematic review of the clinical validity and clinical utility of DNA testing  for hereditary haemochromatosis in at-risk populations
Bryant J, et al.
J Med Genet 2008 Feb

Genetic screening in reproductive health care
Mennuti MT
Clin Obstet Gynecol 2008 Mar;51(1):3-23

 

Probability of BRCA1/2 mutation varies with ovarian histology: results from screening 442 ovarian cancer families
Evans DG, et al.
Clin Genet 2008 Feb

Colorectal Adenomas in Young Patients: Microsatellite Instability is not a Useful Marker to Detect New Cases of Lynch Syndrome
Ferreira S, et al.
Dis Colon Rectum 2008 Feb

 

Selection of Influential Genetic Markers Among a Large Number of Candidates Based on Effect Estimation Rather than Hypothesis Testing: An Approach for Genome-Wide  Association Studies Stromberg U, et al.
Epidemiology 2008 Feb

Whole-genome association study of bipolar disorder
Sklar P, et al.
Mol Psychiatry 2008 Mar

Newly identified genetic risk variants for celiac disease related to the immune response
Hunt KA, et al.
Nat Genet 2008 Mar

Genome-wide association for methamphetamine dependence: convergent results from 2 samples
Uhl GR, et al.
Arch Gen Psychiatry 2008 Mar;65(3):345-55

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending March 5, 2008, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorder
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Diseases of the Musculoskeletal System and Connective Tissue

For more information on HuGE, please visit the HuGENet™ home page