The U.S. Departments of the Treasury, Labor, and Health and Human Services request comments regarding sections 101 through 104 of the Genetic Information Nondiscrimination Act of 2008. The deadline for comments is December 9.
	New article, Health-Related Direct-to-Consumer Genetic Tests: A Public Health Assessment and Analysis of Practices Related to Internet-Based Tests for Risk of Thrombosis, published in the November 2008 issue of Public Health Genomics. Authors: Goddard KAB, Robitaille J, Dowling N, Parrado AR, Fishman J, et al.
	Special December 2008 supplement of Obesity including 16 articles on topics from genetics studies using animal models to prevention and treatment of obesity in humans. This supplement is based on proceedings of the “Gene-Nutrition and Gene-Physical Activity Interactions in the Etiology of Obesity” workshop sponsored by the NCI’s Division of Cancer Control and Population Sciences.
	New article, Learning the Universe of Genetic Testing,(1.3 MB)published in the November 30, 2008 issue of AAPA News. See quotes by Francis Collins, MD, PhD, Wylie Burke, MD, PhD, Greg Ferro, MD, and Muin J. Khoury, MD, PhD.
	New training program in clinical and public health genomics at the Netherlands Institute for Health Sciences
	Summer Institute in Genetic Epidemiology at the Washington University in St. Louis School of Medicine offers all-expense-paid training and mentoring in genetic epidemiology to junior-level faculty and scientists.
	New genetics fellowship position with CDC’s Division of Laboratory Systems in the National Center for Preparedness, Detection, and Control of Infectious Disease. Read the announcement. (75 KB) For more information, contact Ira Lubin at ilubin@cdc.gov.

• The following are headlines from on-line news articles published during the past week.
• The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
• Free registration required for some articles.

Invited Commentary: From Genome-Wide Association Studies to Gene-Environment-Wide Interaction Studies--Challenges and Opportunities Khoury MJ & Wacholder S Am J Epidemiol 2008 Nov

A Decade of Public Health Genomics in the United States: Centers for Disease Control and Prevention 1997-2007
Khoury MJ, et al.
Public Health Genomics 2008 Sep

Canada: Public Health Genomics
Little J, et al.
Public Health Genomics 2009;12(2):112-20

Programs for calculating the statistical powers of detecting susceptibility genes in case-control studies based on multistage designs
Kitamura N, et al.
Bioinformatics 2008 Nov

Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: A systematic in-depth review
Boes E, et al.
Exp Gerontol 2008 Nov

Personalizing Nutrigenomics Research through Community Based Participatory Research and Omics Technologies
McCabe-Sellers B, et al.
OMICS 2008 Dec;12(4):263-72

Nutrigenomics and Ethics Interface: Direct-to-Consumer Services and Commercial Aspects
Ries NM & Castle D
OMICS 2008 Dec;12(4):245-50

Mannose-binding lectin genetics: from A to Z
Garred P
Biochem Soc Trans 2008 Dec;36(Pt 6):1461-6

Pharmacogenetics and breast cancer endocrine therapy: CYP2D6 as a predictive factor for tamoxifen metabolism and drug response?
Stearns V & Rae JM
Expert Rev Mol Med 2008;10:e34

The Virtues of a Deliberately Misspecified Disease Model in Demonstrating a Gene-Environment Interaction
Burstyn I, et al.
Occup Environ Med 2008 Nov

Gene-Environment Interaction in Genome-Wide Association Studies
Murcray CE, et al.
Am J Epidemiol 2008 Nov

Invited Commentary: Efficient Testing of Gene-Environment Interaction
Chatterjee N & Wacholder S
Am J Epidemiol 2008 Nov

Gene-environment interaction and obesity
Qi L & Cho YA
Nutr Rev 2008 Dec;66(12):684-94

Genetic determination of irritable bowel syndrome
Hotoleanu C, et al.
World J Gastroenterol 2008 Nov;14(43):6636-40

Hereditary hemochromatosis
Fix OK & Kowdley KV
Minerva Med 2008 Dec;99(6):605-17

Prioritizing Risk Pathways: A Novel Association Approach to Searching for Disease Pathways Fusing SNPs and Pathways
Chen L, et al.
Bioinformatics 2008 Nov

Implications of gene-drug interactions in smoking cessation for improving the prevention of chronic degenerative diseases
Quaak M, et al.
Mutat Res 2008 Nov

Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction
Andreassi MG
Mutat Res 2008 Nov

Generalized linear modeling with regularization for detecting common disease rare haplotype association
Guo W & Lin S
Genet Epidemiol 2008 Nov

A likelihood ratio test of population Hardy-Weinberg equilibrium for case-control studies
Yu C, et al.
Genet Epidemiol 2008 Nov

Phenotypic variations on the theme of CNVs
O'Donovan MC, et al.
Nat Genet 2008 Dec;40(12):1392-3

Family History Questionnaires Designed for Clinical Use: A Systematic Review
Reid GT, et al.
Public Health Genomics 2009;12(2):73-83

Family history of acute appendicitis
Ergul E, et al.
J Pak Med Assoc 2008 Nov;58(11):635-7

Family history of cancer predicts Papanicolaou screening behavior for African American and white women
Williams KP, et al.
Cancer 2008 Nov

Family history of breast cancer and all-cause mortality after breast cancer diagnosis in the Breast Cancer Family Registry
Chang ET, et al.
Breast Cancer Res Treat 2008 Nov

A population-based case-control study of the familial risk of abdominal aortic aneurysm
Larsson E, et al.
J Vasc Surg 2008 Nov

Sibling and parental history in type 2 diabetes risk among ethnic Chinese: the Chin-Shan Community Cardiovascular Cohort Study
Chien KL, et al.
Eur J Cardiovasc Prev Rehabil 2008 Nov

 

Clinical guidelines versus universal molecular testing: are we ready to choose an optimal strategy for lynch syndrome identification?
Byfield SA & Syngal S
Am J Gastroenterol 2008 Nov;103(11):2837-40

Changes in Diet and Physical Activity Following BRCA1/2 Testing
O'Neill SC, et al.
J Psychosoc Oncol 2008;26(3):63-80

Health-Related Direct-to-Consumer Genetic Tests: A Public Health Assessment and Analysis of Practices Related to Internet-Based Tests for Risk of Thrombosis
Goddard KA, et al.
Public Health Genomics 2009;12(2):92-104

Genetic Screening: Programs, Principles, and Research - Thirty Years Later. Reviewing the Recommendations of the Committee for the Study of Inborn Errors of  Metabolism (SIEM)
Simopoulos AP
Public Health Genomics 2009;12(2):105-11

Can genetic testing guide treatment in breast cancer?
Tutt A & Ashworth A
Eur J Cancer 2008 Nov

Genetic Testing Before Serologic Screening in Relatives of Patients With Celiac Disease as a Cost Containment Method
Chang M & Green PH
J Clin Gastroenterol 2008 Nov

Uptake of clinical genetic testing for ovarian cancer in Ontario: A population-based study
Metcalfe KA, et al.
Gynecol Oncol 2008 Nov

The impact of familial environment on depression scores after genetic testing for cancer susceptibility
Ashida S, et al.
Clin Genet 2008 Nov

 

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum
Gieger C, et al.
PLoS Genet 2008 Nov;4(11):e1000282

Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci
Lei SF, et al.
Hum Genet 2008 Nov

A Genome-Wide Association Study of Schizophrenia Using Brain Activation as a Quantitative Phenotype
Potkin SG, et al.
Schizophr Bull 2008 Nov

Human genetic selection on the MTHFR 677C>T polymorphism
Mayor-Olea A, et al.
BMC Med Genet 2008 Nov;9(1):104

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