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Thursday, September 20, 2007 |
Volume
19 Number 12 |
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This weekly update provides information about the impact of human genetic research on disease prevention & public health. |
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New article, Most Science Studies Appear to Be Tainted By Sloppy
Analysis, published in the Wall Street Journal, quoting John Ioannidis, MD, PhD, Muin J. Khoury, MD, PhD, and other experts. |
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The U.S. Department of Health and Human Services releases new report, Personalized Health Care: Opportunities, Pathways, Resources, presenting a “long-range plan for achieving much more individualized treatment for patients, especially by using genetic information and health information technology.” Read the news release |
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What's New in HuGENet™
September 2007 |
- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Cancer |
Gene chip helps doctor target cancer treatment,
(last accessed 2/2008) Reuters Health, September 19 |
Genetics hold promise, challenges for cancer
care, Medline Plus, September 16 |
Gene profiling can single out the worst cases of multiple myeloma and guide therapy, EurekAlert, September 18 |
Linchpin gene may be useful target for breast cancer therapies, Medical News Today, September 16 |
Test for lung cancer looks for discomforting quiet among protective genes, EurekAlert, September 18 |
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Ethical, Legal, and Social Issues (ELSI) |
Concern over DNA database access, BBC News, September 17 |
Gene therapy death draws scrutiny, CBS News, September 17 |
Gene logic helping FDA in standardizing genomic data,
(last accessed 2/2008) BioWorld Today, September 17 |
Call for more genetic research in the sport and exercise sciences, News-Medical.Net, September 14 |
Other News |
Closing in on genes involved with rheumatoid arthritis, Science Daily, September 20 |
New method speeds up gene discovery, pinpoints cholesterol gene, Medical News Today, September 17 |
Drug resistance gene has spread from East Coast to Midwest, EurekAlert, September 19 |
Genetic variant linked to odor perception, EurekAlert, September 16 |
Scientists identify cause of Job's syndrome, NIH News, September 19 |
Hepatitis-promoting protein caught in the act, The News-Gazette,com, September 16 |
Cautious optimism for sufferers of joint pain, New York Times, September 18 |
The importance of gene regulation for common human disease, EurekAlert, September 16 |
Mutations in the glucocerebrosidase gene are risk factors for Parkinson's disease, News-Medical.Net, September 18 |
Making gene therapy safer: delivering genes via polymers, Science Daily, September 16 |
Researchers discover gene mutation thought to control energy levels, Medical News Today, September 18 |
Discovery of gene responsible for binocular
vision, News-Medical.Net, September 14 |
Targeted Genetics reports on recombinant DNA advisory committee (RAC) review of its phase 1/2 trial of TgAAC94 for rheumatoid arthritis, Medical News Today, September 18 |
Gene Logic teams up with FDA to explore genomic data quality, Reuters, September 14 |
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Genetic factors in pain and its treatment
Stamer UM & Stuber F
Curr Opin Anaesthesiol 2007 Oct;20(5):478-84
Probability of detecting disease-associated single nucleotide polymorphisms in case-control genome-wide association studies
Gail MH, et al.
Biostatistics 2007 Sep
Log-linear model based multifactor dimensionality reduction method to detect gene-gene interactions
Lee SY, et al.
Bioinformatics 2007 Sep
Genetics of Alzheimer's disease. A rapidly evolving field
Serretti A, et al.
J Alzheimers Dis 2007 Sep;12(1):73-92
Polymorphisms in the endothelial protein C receptor gene and thrombophilia
Medina P, et al.
Thromb Haemost 2007 Sep;98(3):564-9
Current pharmacogenetic developments in oral anticoagulation therapy: The influence of variant VKORC1 and CYP2C9 alleles
Oldenburg J, et al.
Thromb Haemost 2007 Sep;98(3):570-8
Recent advances in genetic analysis of multiple sclerosis: genetic associations and therapeutic implications
Niino M, et al.
Expert Rev Neurother 2007 Sep;7(9):1175-88
C-reactive protein gene polymorphisms, C-reactive protein blood levels, and cardiovascular disease risk
Hage FG & Szalai AJ
J Am Coll Cardiol 2007 Sep;50(12):1115-22
Accurate Prediction of Deleterious Protein Kinase Polymorphisms
Torkamani A & Schork NJ
Bioinformatics 2007 Sep
Developing Effective Screening Strategies in Multiple Endocrine Neoplasia Type 1 (MEN 1) on the Basis of Clinical and Sequencing Data of German Patients with MEN 1
Schaaf L, et al.
Exp Clin Endocrinol Diabetes 2007 Sep;115(8):509-17
How the I1307K adenomatous polyposis coli gene variant contributes in the assessment of risk of colorectal cancer, but not stomach cancer, in a Turkish population
Dundar M, et al.
Cancer Genet Cytogenet 2007 Sep;177(2):95-7
Combination of enzyme analysis, allele-specific PCR and sequencing to detect mutations in the GALT gene
Calderon FR, et al.
J Inherit Metab Dis 2007 Sep
Executive function and genetic predisposition to schizophrenia-the Maudsley family study
Birkett P, et al.
Am J Med Genet B Neuropsychiatr Genet 2007 Sep
Genetic variation in five genes important in telomere biology and risk for breast cancer
Savage SA, et al.
Br J Cancer 2007 Sep;97(6):832-6
The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified
Li WF, et al.
Breast Cancer Res Treat 2007 Sep
Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with increased risk for oral cancer
Vairaktaris E, et al.
Acta Oncol 2007 May:1-6
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