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 Thursday, October 11, 2007 Volume 19   Number 15
Weekly Update banner Family History Population Research Genomics in Practice General Public
This weekly update provides information about the impact of human genetic research on disease prevention & public health.
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 Upcoming Events

EpiGenetics 2007 Australian Scientific Conference  non-gov warning icon

American Society of Human Genetics 57th Annual Meeting  non-gov warning icon

Genome Informatics non-gov warning icon (last accessed 2/2008)



 Let's Go Surfing

Your Family History & Breast Cancer, Oregon Genetics Program  you will need a free version of Acrobat Reader to view this file (121KB)

Controversy Arises About Advertisement Campaign for BRCA Genetic Testing, Michigan Cancer Consortium non-gov warning icon you will need a free version of Acrobat Reader to view this file (207KB)

Exploring the gene scene non-gov warning icon

HuGE Navigator

New Online Database: HuGE Navigator
HuGE Navigator non-gov warning icon provides access to a continuously updated knowledge base in human genome epidemiology, including

information on population prevalence of genetic variants, gene-disease associations, gene-gene and gene-environment interactions, and evaluation of genetic tests.

Genomics Announcements
   
CDC-sponsored event

Join the Mid-West Community Genetics Forum on Genomics, Community and Equity: A Continuing Dialogue non-gov warning icon presented by the University of Michigan, Center for Public Health and Community Genomics on October 12th, 2007. Forums will be held in Illinois, Iowa, Michigan, Minnesota, and Missouri.

   
CDC-sponsored event
 
October public health genomics seminar presented by CDC
"Can we use family history as a tool for disease prevention and public health?"
Oct 18, 2007, Rockville, MD (ENVISION – Atlanta, GA)
   


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
Featured Item 3 Win Nobel in Medicine for Gene Technologynon-gov warning icon New York Times, October 9

Cancer

Three new genes discovered that cause lung cancernon-gov warning icon Medical News Today, October 9

HMMR gene emerges as a key player in breast cancernon-gov warning icon News-Medical.Net, October 8

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Ethical, Legal, and Social Issues (ELSI)

NHGRI funds new centers for excellence in ethical, legal and social implications research, NIH News, October 10

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Genetic Testing

Personalizing prescriptions: Genetic tests help doctors find right dose of medicine, non-gov warning icon South Bend Tribune, October 10

Genetic breast cancer testing brings controversy, non-gov warning icon (last accessed 2/2008) Yahoo News, October 9

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Other News

Better understanding of what genomic changes paved the way for modern humans, non-gov warning icon News-Medical.Net, October 9

KGI professor contributes new insights on 'jumping genes', non-gov warning icon EurekAlert, October 8

Bioengineer examines genetic basis for malevolent behavior, non-gov warning icon Medical News Today, October 9

Emory scientists awarded $3m for autism gene research, non-gov warning icon Medical News Today, October 5

Genetics' super summer, non-gov warning icon Channel News Asia, October 9

Largest study of child health ever conducted in the United States, non-gov warning icon News-Medical.Net, October 4

Researchers expand efforts to explore functional landscape of the human genome, NIH News, October 9

Gene-chip studies provide new leads in treating abnormal lung development in premature newborns, non-gov warning icon News-Medical.Net, October 4

Carriers of 'plaque' gene at greater risk, non-gov warning icon Science Daily, October 8 Researchers identify genes that increase rheumatoid arthritis risk, NIH News, October 4

Financial choices influenced by genes, non-gov warning icon International Herald Tribune, October 8

 
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Genomics in Scientific Literature
Featured Item

The Framingham Heart Study, on its way to becoming the gold standard for Cardiovascular Genetic Epidemiology?
Jaquish CE
BMC Med Genet 2007 Oct;8(1):63

 General Articles

Genetics of Ankylosing Spondylitis: An Update
Rahman P
Curr Rheumatol Rep 2007 Oct;9(5):383-9

ADHD Genetics: 2007 Update
Elia J & Devoto M
Curr Psychiatry Rep 2007 Oct;9(5):434-9

Genetics and smoking behavior
Schnoll RA, et al.
Curr Psychiatry Rep 2007 Oct;9(5):349-57

Validity of models for predicting BRCA1 and BRCA2 mutations
Parmigiani G, et al.
Ann Intern Med 2007 Oct;147(7):441-50

Participation bias and its impact on the assembly of a genetic specimen repository for a myocardial infarction cohort
Arruda-Olson AM, et al.
Mayo Clin Proc 2007 Oct;82(10):1185-91

The Framingham Heart Study, on its way to becoming the gold standard for Cardiovascular Genetic Epidemiology?
Jaquish CE
BMC Med Genet 2007 Oct;8(1):63

Interleukin-6 -174G/C Polymorphism and Ischemic Stroke. A Systematic Review
Tso AR, et al.
Stroke 2007 Oct

Fine Mapping versus Replication in Whole-Genome Association Studies
Clarke GM, et al.
Am J Hum Genet 2007 Nov;81(5):995-1005

Haplotype-Based Association Analysis via Variance-Components Score Test
Tzeng JY & Zhang D
Am J Hum Genet 2007 Nov;81(5):927-38

A randomization test for controlling population stratification in whole-genome association studies
Kimmel G, et al.
Am J Hum Genet 2007 Nov;81(5):895-905

Practical aspects of delivering hereditary cancer risk counseling
Demarco TA, et al.
Semin Oncol 2007 Oct;34(5):369-78

 

 Genetic Testing

Ethical and legal aspects of cancer genetic testing
Offit K & Thom P
Semin Oncol 2007 Oct;34(5):435-43

Psychosocial and behavioral impact of genetic counseling and testing
Vadaparampil ST, et al.
Breast Dis 2007;27:97-108

International perspectives on genetic counseling and testing for breast cancer risk
Meiser B, et al.
Breast Dis 2007;27:109-25

Life After BRCA1/2 Testing: Family Communication and Support Issues
Demarco TA & McKinnon WC
Breast Dis 2007;27:127-36

Genetic screening for iron overload: No evidence of discrimination at 1 year
Hall MA, et al.
J Fam Pract 2007 Oct;56(10):829-34

 

 Family History

Do physicians take action on high risk family history information provided by patients outside of a clinic visit?
Volk LA, et al.
Stud Health Technol Inform 2007;129:13-7

Familial concordance in cancer survival: a Swedish population-based study
Lindstrom LS, et al.
Lancet Oncol 2007 Oct

Familial aggregation of left main coronary artery disease and future risk of coronary events in asymptomatic siblings of affected patients
Fischer M, et al.
Eur Heart J 2007 Oct

Value of database linkage: are patients at risk of familial colorectal cancer being referred for genetic counselling and testing?
Wong C, et al.
Intern Med J 2007 Oct

Breast cancer screening compliance among young women in a free access healthcare  system
Amin A, et al.
J Surg Oncol 2007 Oct

Contribution of inherited heart disease to sudden cardiac death in childhood
Hofman N, et al.
Pediatrics 2007 Oct;120(4):e967-73

Family history of asthma and atopy: in-depth analyses of the impact on asthma and wheeze in 7- to 8-year-old children
Bjerg A, et al.
Pediatrics 2007 Oct;120(4):741-8

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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending October 10, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Diseases of the Blood and Blood-Forming Organs Disorders
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Digestive System
Diseases of the Genitourinary System
Complications of Pregnancy, Childbirth, and the Puerperium
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies

For more information on HuGE, please visit the HuGENet™ home page

 

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Page last reviewed: October 11, 2005 (archived document)
Content Source: National Office of Public Health Genomics