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Thursday, November 29, 2007 |
Volume
19 Number 21 |
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This weekly update provides information about the impact of human genetic research on disease prevention & public health. |
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NOPHG Announces New Funding Opportunity
CDC's National Office of Public Health Genomics announces a new funding opportunity for those interested in genomics translation research.
> Read more |
EGAPP Stakeholders Group
The CDC's National Office of Public Health Genomics announces the first meeting of the Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Stakeholders Group (ESG).
> Read more |
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New report, “Family history as a risk factor for common, complex
disease,” produced by the PHG Foundation. Author: Adam Butterworth. |
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New podcast, “Family History – An Early Warning for Your Child,” produced by CDC’s National Center on Birth Defects and Developmental Disabilities. |
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New Genomics Forum of the American Public Health Association was approved this month. Interested individuals can join for free |
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The Secretary’s Advisory Committee on Genetics, Health, and Society invites input on the Committee’s draft report, U.S. System of Oversight of Genetic Testing: A Response to the Charge of the Secretary of HHS, by December 21, 2007. |
- The following are headlines from on-line news articles published during the past week.
- The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
- Free registration required for some articles.
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Cancer |
Ethnic and racial disparities in colorectal cancer risk may be genetic, Medical News Today, November 29 |
BRCA genes raise breast cancer risk for men
too, Reuters Health, November 27 |
Genetic and behavioral differences add to prostate cancer disparities, Medical News Today, November 29 |
More accurate method of estimating breast cancer risk in African American women developed, NIH News, November 27 |
New perspectives on health disparities in breast cancer research, EurekAlert, November 28 |
Cancer drug works by overactivating cancer gene, Medical News Today, November 21 |
Breast cancer risk underestimated for blacks, study says, Washington Post, November 28 |
Genetics and Risk, This Week on Your Cancer Today™,
(last accessed 2/2008) Broadcast Newsroom, November 16 |
Breast cancer gene, smoking link 'high', National Nine News, November 27 |
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Ethical, Legal and Social Issues (ELSI) |
UW-Madison scientists guide human skin cells to embryonic state, EurekAlert, November 20 |
Threats to your genetic privacy, U.S. News & World Report, November 16 |
Race, genetics could 'disrupt' pursuit of using DNA to tailor medicine, health care, opinion piece says, Medical News Today, November 16 |
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Genetic Testing |
Aetna to offer access to confidential telephonic cancer genetic counseling to health plan
members, Aetna, November 27 |
The serious business of gene tests, Yahoo Finance, November 19 |
Pre-marital tests do not solve genetic risks,
(last accessed 2/2008) GulfNews.com, November 21 |
My Genome, Myself: Seeking clues in DNA, The New York Times, November 17 |
Google-backed 23andMe offers $999 DNA test,
(last accessed 2/2008) USA Today, November 20 |
Company offers genome assessments, The New York Times, November 16 |
Retail genomics within spitting distance, Economist.com, November 20 |
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Mental Health |
Brain pattern associated with genetic risk of Obsessive Compulsive Disorder, Science Daily, November 26 |
Major U.S. autism study gets under way, Washingtonpost.com, November 16 |
Brain function in Parkinson's patients normalized by gene therapy, Medical News Today, November 20 |
Study links asthma and post-traumatic stress disorder, EurekAlert, November 15 |
Variant of CDC2 gene may be potential risk marker for Alzheimer's, News-Medical.Net, November 20 |
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Other News |
Litinspector: Quick and easy retrieval of pathways, genes, gene functions, gene-gene interactions and more, Medical News Today, November 29 |
Evolutionary comparison finds new human
genes, Medical News Today, November 21 |
Breathe deep: Which patients could benefit from inhaled steroids in cystic fibrosis, EurekAlert, November 28 |
Top Washington health officials to honor Framingham heart study participants, Medical News Today, November 21 |
A flare for gene silencing, Nanowerk, November 28 |
Tumornators rock to fight rare genetic nerve disease, Redandblack.com, November 20 |
Mexican Americans carrying Haplotype H6 of the CYP2E1 gene have a greater risk of alcoholism, Medical News Today, November 27 |
Scientists decode genes of resistant TB,
(last accessed 2/2008) Reuters Health, November 20 |
U.S. gene therapy study to continue, International Herald Tribune, November 26 |
Breakthrough in organ rejection diagnosis examines gene behavior, Medical News Today, November 20 |
Gene research sheds light on Huntington’s
disease, Himtimes, November 24 |
Coordinate gene regulation during Hematopoiesis is related to genomic organization, Medical News Today, November 19 |
Rebuilding the evolutionary history of HIV-1 unravels a complex loop, EurekAlert, November 23 |
Genomic Instability, Human RecQ Helicases and Homologous Recombination, Medical News Today, November 15 |
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PedGenie: meta genetic association testing in mixed family and case-control designs
Curtin K, et al.
BMC Bioinformatics 2007 Nov;8(1):448
MDRView: a visualization of the polymorphisms of MDR1(ABCB1) GENE in breast cancer
Edlira X, et al.
Conf Proc IEEE Eng Med Biol Soc 2007;1:4592-4
Negative Selection on BRCA1 Susceptibility Alleles Sheds Light on the Population Genetics of Late-Onset Diseases and Aging Theory
Pavard S & Metcalf CJ
PLoS ONE 2007;2(11):e1206
Race, genetics and medicine: does the color of a leopard's spots matter?
Bamshad M & Guthery SL
Curr Opin Pediatr 2007 Dec;19(6):613-8
The genetic basis of psoriasis
Valdimarsson H
Clin Dermatol 2007 Nov-2007 Dec;25(6):563-7
Studies of association in complex diseases: Statistical problems related to the analysis of genetic polymorphisms
Salas A & Carracedo A
Rev Clin Esp 2007 Dec;207(11):563-5
CYP2D6 polymorphism: implications for antipsychotic drug response, schizophrenia and personality traits
Dorado P, et al.
Pharmacogenomics 2007 Nov;8(11):1597-608
Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations
Fackenthal JD & Olopade OI
Nat Rev Cancer 2007 Dec;7(12):937-48
Breakthroughs in genetic studies of ankylosing spondylitis
Brown MA
Rheumatology (Oxford) 2007 Nov
Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes
Nordgard SH, et al.
Breast Cancer Res 2007 Nov;9(6):113
beta-Adrenergic receptor polymorphisms: relationship to the beta-agonist controversy and clinical implications
Taylor DR
Expert Opin Pharmacother 2007 Dec;8(18):3195-203
Pharmacogenomics in prevention of diabetic cardiovascular disease: utilization of the haptoglobin genotype in determining benefit from vitamin E
Levy AP & Blum S
Expert Rev Cardiovasc Ther 2007 Nov;5(6):1105-11
Family history of diabetes, autoimmunity, and risk factors for cardiovascular disease among children with diabetes in the SEARCH for Diabetes in Youth Study
Gilliam LK, et al.
Pediatr Diabetes 2007 Dec;8(6):354-61
Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism
Mosconi L, et al.
Proc Natl Acad Sci U S A 2007 Nov
Parental history of Type 2 diabetes in patients with nonaffective psychosis
Fernandez-Egea E, et al.
Schizophr Res 2007 Nov
Sex Differences in Heritability of Ischemic Stroke. A Systematic Review and Meta-Analysis
Touze E & Rothwell PM
Stroke 2007 Nov
MRI Screening in a Clinic Population with a Family History of Breast Cancer
Yu J, et al.
Ann Surg Oncol 2007 Nov
Family History of Cancer and Risk of Lung Cancer among Nonsmoking Chinese Women
Zhang Y, et al.
Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2432-5
Sex- and Kindred-Specific Familial Risk of Non Hodgkin's Lymphoma
Czene K, et al.
Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2496-9
Aggregation of cancer in first-degree relatives of patients with glioma
Scheurer ME, et al.
Cancer Epidemiol Biomarkers Prev 2007 Nov;16(11):2491-5
Cancer Risk Management Practices of Noncarriers Within BRCA1/2 Mutation Positive Families in the Kathleen Cuningham Foundation Consortium for Research Into Familial Breast Cancer
Dawson SJ, et al.
J Clin Oncol 2007 Nov
Cancer risk reduction and reproductive concerns in female BRCA1/2 mutation carriers
Staton AD, et al.
Fam Cancer 2007 Nov
Genetic testing for melanoma predisposition: current challenges
Gerstenblith MR, et al.
Cancer Nurs 2007 Nov-2007 Dec;30(6):452-9
Results communication and patient education after screening for possible hemochromatosis and iron overload: experience from the HEIRS Study of a large ethnically and linguistically diverse group
Walker AP, et al.
Genet Med 2007 Nov;9(11):778-91
Barriers to participating in genetic counseling and BRCA testing during primary treatment for breast cancer
Schlich-Bakker KJ, et al.
Genet Med 2007 Nov;9(11):766-77
Toxicogenetics of antiretroviral therapy: genetic factors that contribute to metabolic complications
Tarr PE & Telenti A
Antivir Ther 2007;12(7):999-1013
Assessing hypothetical scenario methodology in genetic susceptibility testing analog studies: a quantitative review
Persky S, et al.
Genet Med 2007 Nov;9(11):727-38
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