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 Thursday, June 14, 2007     Volume 18   Number 24  
Genomics & Health Weekly Update Genomics & Health Weekly Update Family History Genomics & Health Weekly Update Family History Population Research Genomics in Practice General Public
  This weekly update provides information about the impact of human genetic research on disease prevention & public health. open mailbox for email deliveryGet email updates
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Skin cancer is the most common form of cancer in the United States. Most skin cancers are caused by exposure to ultraviolet rays from the sun.
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Sunburn Prevalence Among Adults -- United States 1999, 2003, and 2004, MMWR, June 1, 2007   pdf icon (310KB)
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blue dotAnnouncements
blue dotGenomics In The News
blue dotScientific Literature
blue dotHuGE Articles
blue dotBack Issues

 
Genomics Announcements
   

bullhorn

New June issue of PHG Foundation's monthly newsletter, featuring genomics and policy news
   
CDC sponsored material
 New HuGE case study on obesity and genetic testing: Using Whole Genome Scans to Discover Obesity Genes: Implications for the Clinical Utility of Genetic Testing in Obesity
   

CDC sponsored material

New book review of Battle of the Genomes: The Struggle for Survival in a Microbial World written by Marta Gwinn, MD, MPH, of CDC’s National Office of Public Health Genomics, was published in the June 2007 issue of the Emerging Infectious Diseases journal.
   
CDC sponsored material
 What's New in HuGENet™
June 2007


Genomics In The News

  • The following are headlines from on-line news articles published during the past week.
  • The headlines and lead sentence are exactly as they appear in the popular press & do not necessarily reflect the opinions or recommendations of CDC.
  • Free registration required for some articles.
line
 Chronic Disease

Gene mutation slashes prostate cancer survival
time, non-gov warning icon New Scientist, June 13

 Genetic defect links respiratory disease and congenital heart disease, non-gov warning icon EurekAlert, June 11
Gene switched off in cancer can be turned on, non-gov warning icon
Medical News Today, June 12

Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway, non-gov warning icon EurekAlert, June 11
Sun exposure early in life linked to specific skin cancer gene mutation, non-gov warning icon Medical News Today, June 11 Cancer gene pathway triggers micro RNAS to suppress tumors, non-gov warning icon Medical News Today, June 9
Comorbidities common in bipolar disorder may have genetic link, non-gov warning icon Science Daily, June 11 Gene variations point to why lung cancer drugs work better in Japanese vs. US patients, non-gov warning icon Medical News Today, June 7


 Family History
 Genetic Testing
Genomics called key on asthma, non-gov warning icon Red Orbit, June 10
Genetic testing helps families fight cancer, Star Tribune, June 10


 Other News

DNA Sequences That Bind Proteins To Engage Gene Transcription - More Green Lights, non-gov warning icon Medical News Today, June 14

Identification of genetic risk factor for Coeliac disease promises improved treatment, non-gov warning icon EurekAlert, June 10

UVa researchers restore genes in human inner ear cells, non-gov warning icon EurekAlert, June 14

 Sleeping beauty 'Jumping gene' shows promise for Sickle Cell gene therapy, non-gov warning icon Science Daily, June 10
Experiments To Annotate All 399 Protein-Coding Genes - Pervasive Transcription, Fewer
Boundaries, non-gov warning icon Medical News Today, June 14

Insurance companies should have access to genetic information, non-gov warning icon Medical News Today, June 8
The wider view from a detailed focus, non-gov warning icon EurekAlert, June 13

Cochlear implant restores hearing to patient with rare genetic disorder, non-gov warning icon Science Daily, June 8
New applied biosystems software accelerates the identification of genetic variants used in biomedical research, non-gov warning icon Yahoo Finance, June 13 (last accessed 01/2008) University of Manchester researchers reveal clues to new genes behind rheumatoid arthritis, non-gov warning icon The University of Manchester, June 7
Researchers reveal structure of protein altered in autism, non-gov warning icon EurekAlert, June 12 Virus widely used in gene therapy research yields important clues to genomic instability, non-gov warning icon Medical News Today, June 7
CA9 gene expression in conventional renal cell carcinoma: A potential marker for prediction of early metastasis after Nephrectomy, non-gov warning icon Medical News Today, June 11 Dietary preferences and patterns may be linked to genes, non-gov warning icon EurekAlert, June 7
Fifth gene responsible for Joubert Syndrome
identified, non-gov warning icon Science Daily, June 11
  
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Genomics in Scientific Literature
Featured Item

Non-Replication and Inconsistency in the Genome-Wide Association Setting
Ioannidis JP
Hum Hered 2007 Jun;64(4):203-13
 General Articles

Impact of genetic factors on outcome from brain injury
Wilson M & Montgomery H
Br J Anaesth 2007 Jun

Replicating genotype-phenotype associations; Editor's summary  (last accessed 2/2008)
Chanock SJ, et al.
Nature 2007 Jun;447(7145):655-60

Activated protein C resistance and factor V Leiden: a review
Rosendorff A & Dorfman DM
Arch Pathol Lab Med 2007 Jun;131(6):866-71

Using Risk-based Sampling to Enrich Cohorts for Endpoints, Genes, and Exposures
Weinberg CR, et al.
Am J Epidemiol 2007 Jun

Genetic variation in human disease and a new role for copy number variants
Shelling AN & Ferguson LR
Mutat Res 2007 May

Genetic determinants of HDL: monogenic disorders and contributions to variation
Klos KL & Kullo IJ
Curr Opin Cardiol 2007 Jul;22(4):344-51

 

 Family History

Genetics of restless legs syndrome (RLS): State-of-the-art and future directions
Winkelmann J, et al.
Mov Disord 2007 Jun

Familial clustering of chronic kidney disease
Satko SG, et al.
Semin Dial 2007 May-2007 Jun;20(3):229-36

 

 Genetic Testing

Should healthcare providers have a duty to warn family members of individuals with an HNPCC-causing mutation? A survey of patients from the Ontario Familial Colon Cancer Registry
Kohut K, et al.
J Med Genet 2007 Jun;44(6):404-7

Attitudes towards predictive genetic testing in minors for familial breast cancer: A systematic review
Borry P, et al.
Crit Rev Oncol Hematol 2007 Jun
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HuGE Published Literature [ back to top ]

Articles that report on population prevalence of genotypes, gene-disease associations, gene-environment and gene-gene interactions and evaluation of genetic tests. For more information on HuGE, please visit the HuGENet™ home page

For the week ending June 13, 2007, there are HuGE articles in the following areas:

Gene Variant Frequency
Infectious and Parasitic Diseases
Neoplasms
Endocrine, Nutritional and Metabolic Diseases
Mental Disorders
Diseases of the Nervous System and Sense Organs
Diseases of the Circulatory System
Diseases of the Respiratory System
Diseases of the Digestive System
Diseases of the Skin and Subcutaneous Tissue
Diseases of the Musculoskeletal System and Connective Tissue
Congenital Anomalies
Injury and Poisoning

For more information on HuGE, please visit the HuGENet™ home page

 

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Page last reviewed: June 14, 2007 (archived document)
Content Source: National Office of Public Health Genomics