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NIOSH Safety and Health Topic:

Nanotechnology

NIOSH-HSE International Symposium Scopes Nanotechnology
Research Needs

By plane, train, bus, and car, some 130 leading international experts from industrial hygiene, toxicology, medicine, chemical engineering, and other diverse disciplines converged on Buxton, England, on Oct. 12-14, 2004.

The expert group gathered for the first-ever International Symposium on Occupational Health Implications of Nanomaterials, sponsored by NIOSH and the Health and Safety Executive (HSE), the United Kingdom’s counterpart to the Occupational Safety and Health Administration in the U.S. (HSE’s Health & Safety Laboratory, NIOSH’s research counterpart in the U.K., is located in Buxton.)

NIOSH and HSE convened the research summit to examine occupational health issues related to the production and use of nanomaterials: What is currently known about potential exposures to nanoparticles in such processes? What more do scientists and policy makers need to know, in order to understand the potential occupational health impacts of this 21 st Century technology?

Nanotechnology “could be the next industrial revolution across the world,” John Ewins, head of the science strategy and statistics division of HSE, said in opening the conference.

In the United States, NIOSH is part of a multi-agency program to advance U.S. leadership in this dynamically growing field by facilitating technology transfer and coordinating research to promote wise stewardship. Through the manipulation of materials at atomic, molecular, and macromolecular levels, nanotechnology makes it possible to create new structures and systems with unique properties and benefits. These include new tools to improve medical diagnosis and treatment, cleaner and more efficient energy sources, more powerful computers, and stronger building materials.

‘Kick-Started This Process’  

Never before had leading researchers from the U.S., Europe, and Asia met strategically to share their latest findings related to the occupational health aspects of nanotechnology, and to lay out the areas of study needed to fill critical gaps. “We got together a really effective group of people with an immense amount of knowledge, and we kick-started this process,” HSE’s Brian Fullam said Oct. 14 in closing remarks.

From three days of scientific presentations and workshop deliberations, several consistent themes emerged:

  • In themselves, studies to date do not provide all the information needed for determining, with confidence, whether nanomaterials have occupational health effects. However, they provide a good springboard for designing new research that will move scientific understanding significantly forward. “I came here thinking there were really major gaps in our knowledge,” Dr. Fullam remarked. “I go home thinking, ‘That’s true, but it’s not true.’ ”
  • To fill existing gaps, collaborative research is needed across different scientific disciplines. For example, studies are needed to better define the properties and behavior of nanoparticles; develop a “metric” for measuring exposure to nanoparticles in ways that correlate with potential health factors; assess the adequacy of personal protective equipment; and better assess the relevance of data from laboratory animal studies for predicting potential human effects.
  • While further research is planned and conducted, makers and users of nanomaterials can take precautionary steps to control exposures, using the traditional risk assessment/risk management approach and instituting controls as appropriate.
  • Tools to measure, assess, and control exposures need to be standardized internationally, to avoid confusion and to promote scientific collaboration.
  • Scientists and policy makers should maintain open communication with the public as research, development, and application of nanotechnology advances. It is important to engage discussion “not only among you as experts in the field,” Mr. Ewins of the HSE told the participants, “but [also to secure] the involvement and the confidence of the public. If we lose the public’s trust about anything, then we are in an uphill battle to recover it.”

2005 Nanotechnology Research Symposium Planned

In partnership with the University of Minnesota, NIOSH will sponsor a Second International Symposium on Nanotechnology and Occupational Health on Oct. 4-6, 2005, in Minneapolis, Minn. www.cce.umn.edu/nanotechnology That conference “is going to be, if anything, more important [than the 2004 symposium] as we look back, see where we have gotten and see what gaps we’ve started to plug, and take another big step forward,” Dr. Fullam commented.

Under the National Nanotechnology Initiative and other partnerships, including membership on the Nanostructured Science, Engineering and Technology subcommittee of the National Science and Technology Council committee on technology, NIOSH conducts a robust program of research on nanotechnology and occupational health. More information is available on the NIOSH nanotechnology topic page at www.cdc.gov/niosh/topics/nanotech/ Presentations and proceedings from the 2004 symposium will be posted on the web page as soon as they become available.

 

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