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Research and Resources
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Guide for Understanding Genetic Conditions
NIH Web Site for New Investigators
NHLBI Research Initiatives
- Bioengineering Approaches to Energy Balance and Obesity
- Cellular and Genetic Discovery Toward Curative Therapy in Myeloproliferative
Disorders (MPD)
- Centers of Excellence in Translational Human Stem Cell Research
- Community Participation in Research
- Critical Issues in Post-Phlebitic Syndrome
- Heart Failure Clinical Research Network
- Infectious Agents in the Origins of Chronic Lung Disease
- Mechanisms of HIV-Related Pulmonary Complications
- Myelodysplastic Syndrome (MDS): Seeking Cure through Discovery on
Pathogenesis and Disease Progression
- SBIR/STTR Technologies for Monitoring and Performing Resuscitation
- Sickle Cell Disease (SCD) Clinical Research Network
- Specialized Centers of Clinically Oriented Research (SCCOR) in Vascular
Injury, Repair, and Remodeling
Need More Information?
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Guide for Understanding Genetic Conditions
The National Library of Medicine (NLM), NIH, offers information about genetic
conditions and the genes or chromosomes responsible for them on its Genetics
Home Reference Web site. The Web site, which was designed for the public,
provides explanations that are easy to understand.
Users can browse topics by specific genetic conditions, genes, or chromosomes.
The site features an online handbook, titled “Help Me Understand Genetics,”
which is an illustrated, basic explanation of how genes work and how mutations
cause disorders. The handbook also includes current information about genetic
testing, gene therapy, and the Human Genome Project. Additional features on
the Web site include a glossary of genetic and medical terms and links to relevant
genetic resources.
NIH Web Site for New Investigators
The Office of Extramural Research, NIH, established a Web
site for new investigators. The site features resources that new investigators
can use to understand and work with the NIH, describes current NIH funding policies,
and provides links to helpful hints for preparing a first application for NIH
support.
NHLBI Research Initiatives
From time to time, the NHLBI invites investigators to submit grant applications
or contract proposals for specific research programs. We are currently soliciting
applications for the programs described below. For a full details of these and
other research initiatives, visit www.nhlbi.nih.gov/funding/inits/index.htm
or the Web page that is linked each initiative number.
Bioengineering Approaches to Energy Balance and Obesity
- Initiative Number: RFA-HL-04-022
- Applications due: February 16, 2005
- Objective: To develop and validate new and innovative bioengineering technology
to address clinical problems related to energy balance, intake, and expenditure.
Cellular and Genetic Discovery Toward Curative Therapy in Myeloproliferative Disorders (MPD)
- Initiative Number: RFA-HL-04-034
- Applications due: February 16, 2005
- Objective: To search for new cellular and genetic markers associated with
the origin and progression of MPD that can be applied to the development of
new therapeutics.
Centers of Excellence in Translational Human Stem Cell Research
- Initiative Number: RFA-NS-05-005
- Applications due: March 24, 2005
- Objective: To accelerate application of the latest advances in human stem
cell biology for the development of diagnostic or therapeutic uses and for
preclinical studies employing human stem cells in animal models of disease.
Community Participation in Research
- Initiative Number: PAR-05-026
- Applications due: May 17, 2005, 2006, and 2007
- Objective: To support research on health promotion, disease prevention,
and health disparities that is jointly conducted by communities and researchers.
Critical Issues in Post-Phlebitic Syndrome
- Initiative Number:
RFA-HL-05-014
- Applications due: May 24, 2005
- Objective: To support research on venous biology and on post-thrombotic
response of the vein wall and valve function, in order to accelerate preclinical
studies and develop better management principles for post-phlebitic syndrome.
Heart Failure Clinical Research Network
- Initiative Number:
RFA-HL-05-003
- Applications due: August 16, 2005
- Objective: To establish a Heart Failure Clinical Research Network that will
expedite clinical research to evaluate the diagnosis, management, and treatment
of heart failure.
Infectious Agents in the Origins of Chronic Lung Disease
- Initiative Number:
RFA-HL-05-005
- Applications due: May 17, 2005
- Objective: To investigate the contribution of infectious agents or infectious
agent-derived bioproducts to the early origin of chronic lung diseases in
humans.
Mechanisms of HIV-related Pulmonary Complications
- Initiative Number:
RFA-HL-04-031
- Applications due: March 16, 2005
- Objective: To encourage innovative research on the roles of co-infections,
immune factors, and genetic predisposition in the pathogenesis of HIV-related
pulmonary diseases.
Myelodysplastic Syndrome (MDS): Seeking Cure through Discovery on Pathogenesis and Disease Progression
- Initiative Number: RFA-HL-04-033
- Applications due: February 16, 2005
- Objectives: To encourage basic research on the pathogenesis and disease
progression of MDS that can be applied to the development of new therapeutics.
SBIR/STTR Technologies for Monitoring and Performing Resuscitation
- Initiative Number: PA-04-059
- Applications due: April 1, 2005; August 1, 2005; and December 1, 2005
- Objective: To encourage small businesses to participate in the development
of new approaches, tools, methods, devices, and biomaterials for monitoring
and performing resuscitation.
Sickle Cell Disease (SCD) Clinical Research Network
- Initiative Number:
RFA-HL-05-006
- Applications due: April 25, 2005
- Objective: To establish a clinical research network that can translate results
from basic and Phase I/II studies into Phase III trials in patients with SCD
and when appropriate, thalasssemia.
Specialized Centers of Clinically Oriented Research (SCCOR) in Vascular Injury, Repair, and Remodeling
- Initiative Number:
RFA-HL-05-001
- Applications due: May 11, 2005
- Objective: To improve prevention, detection, characterization, management,
and treatment of vascular diseases by investigating the molecular and cellular
mechanisms of vascular injury, repair, and remodeling.
Need More Information?
We are always interested in receiving comments and suggestions from the community.
If you or your organizations have questions for me or for the Institute, please
contact me at nabele@nhlbi.nih.gov or Dr. Carl
Roth at rothc@nih.gov.
Elizabeth G. Nabel, M.D.
Director, NHLBI
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