Selected Publications

Ion Channel Physiology Group

1. Pettit, D.L., Shao, Z. & Yakel, J.L. (2001) β-Amyloid 1-42 peptide directly modulates nicotinic receptors in the rat hippocampal slice. J. Neuroscience (Rapid Communication) 21:RC120:1-5.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11150356)
2. Khiroug, S.S., Harkness, P.C., Lamb, P.W., Sudweeks, S.N., Khiroug, L., Millar, N.S., & Yakel, J.L. (2002) Rat nicotinic ACh receptor α7 and β2 subunits co-assemble to form functional heteromeric nicotinic receptor channels. J. Physiology 540: 425-434.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11956333)
3. Sudweeks, S.N., van Hooft, J.A., & Yakel, J.L. (2002) Serotonin 5-HT3 Receptors in Rat CA1 Hippocampal Interneurons: Functional and Molecular Characterization. J. Physiology 544:715-726.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12411518)
4. Khiroug, L., Giniatullin, R., Klein, R.C., Fayuk, D. & Yakel, J.L. (2003) Functional mapping and Ca2+ regulation of nicotinic acetylcholine receptor channels in rat hippocampal CA1 neurons. J. Neuroscience 23: 9024-9031.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14534236)
5. Klein, R.C. & Yakel, J.L. (2004) Inhibition of nicotinic acetylcholine receptors by Apolipoprotein E-derived peptides in rat hippocampal slices. Neuroscience (Rapid Report) 127: 563-567.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15283956)
6. Fayuk, D. & Yakel, J.L. (2004) Regulation of nicotinic acetylcholine receptor channel function by acetylcholinesterase inhibitors in rat hippocampal CA1 interneurons. Mol. Pharm. 66: 658-666.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15322258)
7. Fayuk, D. & Yakel, J.L. (2005) Ca2+ permeability of nicotinic acetylcholine receptors in rat hippocampal CA1 interneurons. J. Physiology 566: 759-768.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15932886)
8. Klein, R.C. & Yakel, J.L. (2005) Paired-pulse potentiation of α7-containing nAChRs in rat hippocampal CA1 stratum radiatum interneurons. J. Physiology 568: 881-889.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16141265)
9. Gay, E.A., Klein, R.C. & Yakel, J.L. (2006) Apolipoprotein E-derived peptides block α7 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J. Pharm. Exp. Ther. 316: 835-842.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16249370)
10. Klein, R.C. & Yakel, J.L. (2006) Functional somato-dendritic α7-containing nicotinic acetylcholine receptors in the rat basolateral amygdala complex. J. Physiology 576: 865-872.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16931547)
11. Fayuk, D. & Yakel, J.L. (2007) Dendritic Ca²⁺ signaling due to activation of α7-containing nicotinic acetylcholine receptors in rat hippocampal neurons. J. Physiology 582: 597-611. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17510177&ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
12. Gay, E.A., Bienstock, R. J., Lamb, P.W. & Yakel, J.L. (2007) Structural determinates for apolipoproteinE–derived peptide interaction with the α7 nicotinic acetylcholine receptor. Mol. Pharm 72:838–849. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17609418&ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
13. Gay, E.A. & Yakel, J.L. (2007) Gating of nicotinic ACh receptors; new insights into structural transitions triggered by agonist binding that induce channel opening. J. Physiology (Topical Review) 584: 727-733. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17823204&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
14. Fayuk D, Yakel JL. (2007) Dendritic Ca2+ signaling due to activation of a7-containing nicotinic acetylcholine receptors in rat hippocampal neurons. The Journal of Physiology Pt 2:597-611. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17510177)
15. Gay EA, Giniatullin R, Skorinkin A, Yakel JL. (2008) Aromatic residues at position 55 of rat alpha7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization. The Journal of physiology 586(4):1105-1115. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18096596)
16. Poisik OV, Shen J-X, Jones S, Yakel JL. (2008) Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia Nigra pars reticulata. The Journal of physiology 586(5):1365-1378. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18202094)
17. Gay EA, Klein RC, Melton MA, Blackshear PJ, Yakel JL. (2008) Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide. The Journal of pharmacology and experimental therapeutics 327(3):884-890. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18812491)

 Back to top