| | This journal provides immediate access to some articles. Commentaries Epithelia: Not just physical barriers Tomas Ganz PMCID: PMC122525 Spliceosomal introns in a deep-branching eukaryote: The splice of life Patricia J. Johnson PMCID: PMC122526 Virus self-improvement through inflammation: No pain, no gain Edward S. Mocarski, Jr. PMCID: PMC122527 Rivers dam waves of rabies Bryan Grenfell PMCID: PMC122528 A new mutator phenotype in breast cancer? Johan G. de Boer PMCID: PMC122529 Physical Sciences Applied Physical Sciences Fast 100-nm resolution three-dimensional microscope reveals structural plasticity of mitochondria in live yeast Alexander Egner, Stefan Jakobs, and Stefan W. Hell PMCID: PMC122530 Chemistry The gas phase reaction of singlet dioxygen with water: A water-catalyzed mechanism Xin Xu, Richard P. Muller, and William A. Goddard, III PMCID: PMC122531 Target-induced formation of neuraminidase inhibitors from in vitro virtual combinatorial libraries Matthias Hochgürtel, Heiko Kroth, Dorothea Piecha, Michael W. Hofmann, Claude Nicolau, Sonja Krause, Otmar Schaaf, Gabriele Sonnenmoser, and Alexey V. Eliseev PMCID: PMC122532 Computer Sciences Algorithmic cooling and scalable NMR quantum computers P. Oscar Boykin, Tal Mor, Vwani Roychowdhury, Farrokh Vatan, and Rutger Vrijen PMCID: PMC122533 Engineering The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells Song Li, Peter Butler, Yingxiao Wang, Yingli Hu, Dong Cho Han, Shunichi Usami, Jun-Lin Guan, and Shu Chien PMCID: PMC122560 Physics Algorithmic cooling and scalable NMR quantum computers P. Oscar Boykin, Tal Mor, Vwani Roychowdhury, Farrokh Vatan, and Rutger Vrijen PMCID: PMC122533 Biological Sciences Applied Biological Sciences Aluminum-dependent regulation of intracellular silicon in the aquatic invertebrate Lymnaea stagnalis Mahmoud Desouky, Ravin Jugdaohsingh, Catherine R. McCrohan, Keith N. White, and Jonathan J. Powell PMCID: PMC122534 Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: A method to modulate gene expression Philipp Mayer-Kuckuk, Debabrata Banerjee, Sundeep Malhotra, Mikhail Doubrovin, Marian Iwamoto, Tim Akhurst, Julius Balatoni, William Bornmann, Ronald Finn, Steven Larson, Yuman Fong, Juri Gelovani Tjuvajev, Ronald Blasberg, and Joseph R. Bertino PMCID: PMC122535 Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences Günter Kraus, Rebeca Geffin, Gina Spruill, Andrea K. Young, Rachel Seivright, Diana Cardona, Jennifer Burzawa, and H. James Hnatyszyn PMCID: PMC122536 Biochemistry Covalent modification of proteins by cocaine Shi-Xian Deng, Narine Bharat, Marian C. Fischman, and Donald W. Landry PMCID: PMC122537 Crystal structure of the OpcA integral membrane adhesin from Neisseria meningitidis Stephen M. Prince, Mark Achtman, and Jeremy P. Derrick PMCID: PMC122538 A mammalian homolog of unc-53 is regulated by all-trans retinoic acid in neuroblastoma cells and embryos R. A. Merrill, L. A. Plum, M. E. Kaiser, and M. Clagett-Dame PMCID: PMC122539 Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus Qiulong Huang, Andrew M. Petros, Herbert W. Virgin, Stephen W. Fesik, and Edward T. Olejniczak PMCID: PMC122540 Arm-site binding by λ-integrase: Solution structure and functional characterization of its amino-terminal domain Jonathan M. Wojciak, Dibyendu Sarkar, Arthur Landy, and Robert T. Clubb PMCID: PMC122541 Stop codons preceded by rare arginine codons are efficient determinants of SsrA tagging in Escherichia coli Christopher S. Hayes, Baundauna Bose, and Robert T. Sauer PMCID: PMC122542 Molecular identification of the insect adipokinetic hormone receptors Frank Staubli, Thomas J. D. Jørgensen, Giuseppe Cazzamali, Michael Williamson, Camilla Lenz, Leif Søndergaard, Peter Roepstorff, and Cornelis J. P. Grimmelikhuijzen PMCID: PMC122543 Solution NMR spectroscopy of [α-15N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence J. Klein-Seetharaman, P. J. Reeves, M. C. Loewen, E. V. Getmanova, J. Chung, H. Schwalbe, P. E. Wright, and H. G. Khorana PMCID: PMC122544 Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 Å resolution: Mimicking the product/substrate of the phospho transfer reactions José Antonio Márquez, Sonja Hasenbein, Brigitte Koch, Sonia Fieulaine, Sylvie Nessler, Robert B. Russell, Wolfgang Hengstenberg, and Klaus Scheffzek PMCID: PMC122545 Structure of spinach chloroplast F1-ATPase complexed with the phytopathogenic inhibitor tentoxin Georg Groth PMCID: PMC122546 Protein–protein interactions monitored in mammalian cells via complementation of β-lactamase enzyme fragments Tom Wehrman, Benjamin Kleaveland, Jeng-Horng Her, Robert F. Balint, and Helen M. Blau PMCID: PMC122547 Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking Lan Guan, Franklin D. Murphy, and H. Ronald Kaback PMCID: PMC122548 Direct real-time evaluation of nitration with green fluorescent protein in solution and within human cells reveals the impact of nitrogen dioxide vs. peroxynitrite mechanisms Michael Graham Espey, Sandhya Xavier, Douglas D. Thomas, Katrina M. Miranda, and David A. Wink PMCID: PMC122549 Engineering a terbium-binding site into an integral membrane protein for luminescence energy transfer José Luis Vázquez-Ibar, Adam B. Weinglass, and H. Ronald Kaback PMCID: PMC122550 Interaction of RNA polymerase with forked DNA: Evidence for two kinetically significant intermediates on the pathway to the final complex Laura Tsujikawa, Oleg V. Tsodikov, and Pieter L. deHaseth PMCID: PMC122551 The tRNA Specificity of Thermus thermophilus EF-Tu Haruichi Asahara and Olke C. Uhlenbeck PMCID: PMC122552 Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes Maddalena Fratelli, Hans Demol, Magda Puype, Simona Casagrande, Ivano Eberini, Mario Salmona, Valentina Bonetto, Manuela Mengozzi, Francis Duffieux, Emeric Miclet, Angela Bachi, Joel Vandekerckhove, Elisabetta Gianazza, and Pietro Ghezzi PMCID: PMC122553 Vanadate trapping of nucleotide at the ATP-binding sites of human multidrug resistance P-glycoprotein exposes different residues to the drug-binding site Tip W. Loo and David M. Clarke PMCID: PMC122554 Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo G. Sebastiaan Winkler, Arnold Kristjuhan, Hediye Erdjument-Bromage, Paul Tempst, and Jesper Q. Svejstrup PMCID: PMC122555 From the Cover:
Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA Tapas K. Hazra, Tadahide Izumi, Istvan Boldogh, Barry Imhoff, Yoke W. Kow, Pawel Jaruga, Miral Dizdaroglu, and Sankar Mitra PMCID: PMC122556 Induction of p57KIP2 expression by p73β Éva Bálint, Andrew C. Phillips, Serguei Kozlov, Colin L. Stewart, and Karen H. Vousden PMCID: PMC122557 Biophysics How the folding rate constant of simple, single-domain proteins depends on the number of native contacts Dmitrii E. Makarov, Craig A. Keller, Kevin W. Plaxco, and Horia Metiu PMCID: PMC122558 Protein unfolding: Rigidity lost A. J. Rader, Brandon M. Hespenheide, Leslie A. Kuhn, and M. F. Thorpe PMCID: PMC122559 The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells Song Li, Peter Butler, Yingxiao Wang, Yingli Hu, Dong Cho Han, Shunichi Usami, Jun-Lin Guan, and Shu Chien PMCID: PMC122560 Ion channel gating: A first-passage time analysis of the Kramers type Igor Goychuk and Peter Hänggi PMCID: PMC122561 Mutation of the myosin converter domain alters cross-bridge elasticity Jan Köhler, Gerhard Winkler, Imke Schulte, Tim Scholz, William McKenna, Bernhard Brenner, and Theresia Kraft PMCID: PMC122562 Structural studies of the scrapie prion protein by electron crystallography Holger Wille, Melissa D. Michelitsch, Vincent Guénebaut, Surachai Supattapone, Ana Serban, Fred E. Cohen, David A. Agard, and Stanley B. Prusiner PMCID: PMC122563 A Gaussian-chain model for treating residual charge–charge interactions in the unfolded state of proteins Huan-Xiang Zhou PMCID: PMC122564 Mechanical force generation by G proteins Ioan Kosztin, Robijn Bruinsma, Paul O'Lague, and Klaus Schulten PMCID: PMC122565 Fold prediction of helical proteins using torsion angle dynamics and predicted restraints Chao Zhang, Jingtong Hou, and Sung-Hou Kim PMCID: PMC122566 Cell Biology Embryonic stem cells and somatic cells differ in mutation frequency and type Rachel B. Cervantes, James R. Stringer, Changshun Shao, Jay A. Tischfield, and Peter J. Stambrook PMCID: PMC122567 Haploinsufficiency of mTR results in defects in telomere elongation Karen S. Hathcock, Michael T. Hemann, Kay Keyer Opperman, Margaret A. Strong, Carol W. Greider, and Richard J. Hodes PMCID: PMC122568 Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert Yie Liu, Hue Kha, Mark Ungrin, Murray O. Robinson, and Lea Harrington PMCID: PMC122569 Neutrophils lacking phosphoinositide 3-kinase γ show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis Michael Hannigan, Lijun Zhan, Zhong Li, Youxi Ai, Dianqing Wu, and Chi-Kuang Huang PMCID: PMC122570 Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration Naoki Itano, Fukiko Atsumi, Takahiro Sawai, Yoichi Yamada, Osamu Miyaishi, Takeshi Senga, Michinari Hamaguchi, and Koji Kimata PMCID: PMC122571 Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines Luca Roz, Marcella Gramegna, Hideshi Ishii, Carlo M. Croce, and Gabriella Sozzi PMCID: PMC122572 Element-specific localization of Drosophila retrotransposon Gag proteins occurs in both nucleus and cytoplasm S. Rashkova, S. E. Karam, and M.-L. Pardue PMCID: PMC122573 Integrins regulate the apoptotic response to DNA damage through modulation of p53 Jean McArthur Lewis, Tony Nguyen Truong, and Martin Alexander Schwartz PMCID: PMC122574 Targeted new membrane addition in the cleavage furrow is a late, separate event in cytokinesis C. B. Shuster and D. R. Burgess PMCID: PMC122575 Immortalization of a primate bipotent epithelial liver stem cell Jean-Etienne Allain, Ibrahim Dagher, Dominique Mahieu-Caputo, Nathalie Loux, Marion Andreoletti, Karen Westerman, Pascale Briand, Dominique Franco, Philippe Leboulch, and Anne Weber PMCID: PMC122576 Characterization of mutant tobacco mosaic virus coat protein that interferes with virus cell-to-cell movement Mohammed Bendahmane, Judit Szécsi, Iju Chen, R. Howard Berg, and Roger N. Beachy PMCID: PMC122577 Developmental Biology Design of an HIV-1 lentiviral-based gene-trap vector to detect developmentally regulated genes in mammalian cells Zhennan Lai, Ina Han, Misun Park, and Roscoe O. Brady PMCID: PMC122578 Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis Seiji Takashima, Masafumi Kitakaze, Masanori Asakura, Hiroshi Asanuma, Shoji Sanada, Fumi Tashiro, Hitoshi Niwa, Jun-ichi Miyazaki, Seiichi Hirota, Yukihiko Kitamura, Takashi Kitsukawa, Hajime Fujisawa, Michael Klagsbrun, and Masatsugu Hori PMCID: PMC122579 The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression Ying Guo, Robert Costa, Heather Ramsey, Trevor Starnes, Gail Vance, Kent Robertson, Mark Kelley, Rolland Reinbold, Hans Scholer, and Robert Hromas PMCID: PMC122580 Ecology From the Cover:
Predicting the spatial dynamics of rabies epidemics on heterogeneous landscapes David L. Smith, Brendan Lucey, Lance A. Waller, James E. Childs, and Leslie A. Real PMCID: PMC122581 Rapid prehistoric extinction of iguanas and birds in Polynesia David W. Steadman, Gregory K. Pregill, and David V. Burley PMCID: PMC122582 From the Cover:
Community-wide distribution of predator–prey interaction strength in kelp forests Enric Sala and Michael H. Graham PMCID: PMC122583 Evolution A new evolutionary scenario for the Mycobacterium tuberculosis complex R. Brosch, S. V. Gordon, M. Marmiesse, P. Brodin, C. Buchrieser, K. Eiglmeier, T. Garnier, C. Gutierrez, G. Hewinson, K. Kremer, L. M. Parsons, A. S. Pym, S. Samper, D. van Soolingen, and S. T. Cole PMCID: PMC122584 Conflicting levels of selection in the accumulation of mitochondrial defects in Saccharomyces cerevisiae Douglas R. Taylor, Clifford Zeyl, and Erin Cooke PMCID: PMC122585 Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis Hiroshi Akashi and Takashi Gojobori PMCID: PMC122586 From the Cover:
A spliceosomal intron in Giardia lamblia Julie E. J. Nixon, Amy Wang, Hilary G. Morrison, Andrew G. McArthur, Mitchell L. Sogin, Brendan J. Loftus, and John Samuelson PMCID: PMC122587 How many named species are valid? John Alroy PMCID: PMC122588 Genetics On the sequencing of the human genome Robert H. Waterston, Eric S. Lander, and John E. Sulston PMCID: PMC122589 Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia Hui Liu, Simon C. Heath, Christina Sobin, J. Louw Roos, Brandi L. Galke, Maude L. Blundell, Marge Lenane, Brian Robertson, Ellen M. Wijsman, Judith L. Rapoport, Joseph A. Gogos, and Maria Karayiorgou PMCID: PMC122590 Enhancer action in trans is permitted throughout the Drosophila genome Ji-Long Chen, Kathryn L. Huisinga, Michaela M. Viering, Sharon A. Ou, C.-ting Wu, and Pamela K. Geyer PMCID: PMC122591 Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus Bernice Porjesz, Laura Almasy, Howard J. Edenberg, Kongming Wang, David B. Chorlian, Tatiana Foroud, Alison Goate, John P. Rice, Sean J. O'Connor, John Rohrbaugh, Samuel Kuperman, Lance O. Bauer, Raymond R. Crowe, Marc A. Schuckit, Victor Hesselbrock, P. Michael Conneally, Jay A. Tischfield, Ting-Kai Li, Theodore Reich, and Henri Begleiter PMCID: PMC122592 A robust inducible-repressible promoter greatly facilitates gene knockouts, conditional expression, and overexpression of homologous and heterologous genes in Tetrahymena thermophila Yuhua Shang, Xiaoyuan Song, Josephine Bowen, Robert Corstanje, Yan Gao, Jacek Gaertig, and Martin A. Gorovsky PMCID: PMC122593 Comprehensive analysis of CpG islands in human chromosomes 21 and 22 Daiya Takai and Peter A. Jones PMCID: PMC122594 The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1 Xiaolan Zhao and Rodney Rothstein PMCID: PMC122595 A screen for dominant mutations applied to components in the Drosophila EGF-R pathway Annabel Guichard, Shaila Srinivasan, Georgianna Zimm, and Ethan Bier PMCID: PMC122596 DNA-dependent protein kinase suppresses double-strand break-induced and spontaneous homologous recombination Chris Allen, Akihiro Kurimasa, Mark A. Brenneman, David J. Chen, and Jac A. Nickoloff PMCID: PMC122597 Quantitative measurement of translesion replication in human cells: Evidence for bypass of abasic sites by a replicative DNA polymerase Sharon Avkin, Sheera Adar, Gil Blander, and Zvi Livneh PMCID: PMC122598 Genetic instability favoring transversions associated with ErbB2-induced mammary tumorigenesis Shiquan Liu, Wenjing Liu, John L. Jakubczak, Gregory L. Erexson, Kenneth R. Tindall, Richard Chan, William J. Muller, Sankar Adhya, Susan Garges, and Glenn Merlino PMCID: PMC122599 Immunology An unusual Fc receptor-related protein expressed in human centroblasts Fabio Facchetti, Marina Cella, Silvana Festa, Daved H. Fremont, and Marco Colonna PMCID: PMC122600 Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes David H. Wagner, Jr., Gisela Vaitaitis, Richard Sanderson, Michelle Poulin, Cathleen Dobbs, and Kathryn Haskins PMCID: PMC122601 Combined expression of pTα and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis Diana Bellavia, Antonio F. Campese, Saula Checquolo, Anna Balestri, Andrea Biondi, Giovanni Cazzaniga, Urban Lendahl, Hans J. Fehling, Adrian C. Hayday, Luigi Frati, Harald von Boehmer, Alberto Gulino, and Isabella Screpanti PMCID: PMC122602 Negative regulation of Lck by Cbl ubiquitin ligase Navin Rao, Sachiko Miyake, Alagarsamy Lakku Reddi, Patrice Douillard, Amiya K. Ghosh, Ingrid L. Dodge, Pengcheng Zhou, Norvin D. Fernandes, and Hamid Band PMCID: PMC122603 Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-β production by fibroblasts Takao Kodera, Tracy L. McGaha, Robert Phelps, William E. Paul, and Constantin A. Bona PMCID: PMC122604 Medical Sciences UBE1L is a retinoid target that triggers PML/RARα degradation and apoptosis in acute promyelocytic leukemia Sutisak Kitareewan, Ian Pitha-Rowe, David Sekula, Christopher H. Lowrey, Michael J. Nemeth, Todd R. Golub, Sarah J. Freemantle, and Ethan Dmitrovsky PMCID: PMC122605 Prions in skeletal muscle Patrick J. Bosque, Chongsuk Ryou, Glenn Telling, David Peretz, Giuseppe Legname, Stephen J. DeArmond, and Stanley B. Prusiner PMCID: PMC122606 Profound defects in pancreatic β-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1α, and Hnf-3β David Q. Shih, Markus Heimesaat, Satoru Kuwajima, Roland Stein, Christopher V. E. Wright, and Markus Stoffel PMCID: PMC122607 Direct external imaging of nascent cancer, tumor progression, angiogenesis, and metastasis on internal organs in the fluorescent orthotopic model Meng Yang, Eugene Baranov, Jin-Wei Wang, Ping Jiang, Xiaoen Wang, Fang-Xian Sun, Michael Bouvet, A. R. Moossa, Sheldon Penman, and Robert M. Hoffman PMCID: PMC122608 Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts Thorsten Berg, Steven B. Cohen, Joel Desharnais, Corinna Sonderegger, Daniel J. Maslyar, Joel Goldberg, Dale L. Boger, and Peter K. Vogt PMCID: PMC122609 Bombesin antagonists inhibit growth of MDA-MB-435 estrogen-independent breast cancers and decrease the expression of the ErbB-2/HER-2 oncoprotein and c-jun and c-fos oncogenes Ana M. Bajo, Andrew V. Schally, Magdalena Krupa, Francine Hebert, Kate Groot, and Karoly Szepeshazi PMCID: PMC122610 The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium Silvia C. Finnemann, Lawrence W. Leung, and Enrique Rodriguez-Boulan PMCID: PMC122611 The Arf tumor suppressor gene promotes hyaloid vascular regression during mouse eye development Robyn N. McKeller, Jennifer L. Fowler, Justine J. Cunningham, Nikita Warner, Richard J. Smeyne, Frederique Zindy, and Stephen X. Skapek PMCID: PMC122612 Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia Peter Chu, Dieter Deforce, Irene M. Pedersen, Youngsoo Kim, Shinichi Kitada, John C. Reed, and Thomas J. Kipps PMCID: PMC122613 Immunization of Aotus monkeys with a functional domain of the Plasmodium falciparum variant antigen induces protection against a lethal parasite line Dror I. Baruch, Benoit Gamain, John W. Barnwell, JoAnn S. Sullivan, Anthony Stowers, G. Gale Galland, Louis H. Miller, and William E. Collins PMCID: PMC122614 MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq Tetsuo Minamino, Toshiaki Yujiri, Naohiro Terada, George E. Taffet, Lloyd H. Michael, Gary L. Johnson, and Michael D. Schneider PMCID: PMC122615 G protein-coupled receptor kinase 4 gene variants in human essential hypertension Robin A. Felder, Hironobu Sanada, Jing Xu, Pei-Ying Yu, Zheng Wang, Hidetsuna Watanabe, Laureano D. Asico, Wei Wang, Shaopeng Zheng, Ikuyo Yamaguchi, Scott M. Williams, James Gainer, Nancy J. Brown, Debra Hazen-Martin, Lee-Jun C. Wong, Jean E. Robillard, Robert M. Carey, Gilbert M. Eisner, and Pedro A. Jose PMCID: PMC122616 Identification of gene function and functional pathways by systemic plasmid-based ribozyme targeting in adult mice Mohammed Kashani-Sabet, Yong Liu, Sylvia Fong, Pierre-Yves Desprez, Shuqing Liu, Guanghuan Tu, Mehdi Nosrati, Chakkrapong Handumrongkul, Denny Liggitt, Ann D. Thor, and Robert J. Debs PMCID: PMC122617 Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation Lynda Elghazi, Corentin Cras-Méneur, Paul Czernichow, and Raphael Scharfmann PMCID: PMC122618 The identification of E2F1-specific target genes Julie Wells, Carrie R. Graveel, Stephanie M. Bartley, Steven J. Madore, and Peggy J. Farnham PMCID: PMC122619 Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex Juan Mucci, Alejandra Hidalgo, Esteban Mocetti, Pablo F. Argibay, M. Susana Leguizamón, and Oscar Campetella PMCID: PMC122620 Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia Geraldine Canny, Ofer Levy, Glenn T. Furuta, Sailaja Narravula-Alipati, Richard B. Sisson, Charles N. Serhan, and Sean P. Colgan PMCID: PMC122621 Deficient Smad7 expression: A putative molecular defect in scleroderma Chunming Dong, Shoukang Zhu, Tao Wang, Woohyun Yoon, Zhiru Li, Rene J. Alvarez, Peter ten Dijke, Barbara White, Fredrick M. Wigley, and Pascal J. Goldschmidt-Clermont PMCID: PMC122622 The quantity of nitric oxide released by macrophages regulates Chlamydia-induced disease Jin Huang, Fred J. DeGraves, Stephen D. Lenz, Dongya Gao, Pu Feng, Dan Li, Tobias Schlapp, and Bernhard Kaltenboeck PMCID: PMC122623 Microbiology Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection Kaman Chan, Timothy Knaak, Laura Satkamp, Olivier Humbert, Stanley Falkow, and Lalita Ramakrishnan PMCID: PMC122624 Ammonium/methylammonium transport (Amt) proteins facilitate diffusion of NH3 bidirectionally Eric Soupene, Haidy Lee, and Sydney Kustu PMCID: PMC122625 From the Cover:
Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication Hua Zhu, Jian-Ping Cong, Deborah Yu, Wade A. Bresnahan, and Thomas E. Shenk PMCID: PMC122626 Chronic intracellular infection of alfalfa nodules by Sinorhizobium meliloti requires correct lipopolysaccharide core Gordon R. O. Campbell, Bradley L. Reuhs, and Graham C. Walker PMCID: PMC122627 Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein Lisa Z. Scheifele, Rachel A. Garbitt, Jonathan D. Rhoads, and Leslie J. Parent PMCID: PMC122628 Neurobiology Some properties of human neuronal α7 nicotinic acetylcholine receptors fused to the green fluorescent protein Eleonora Palma, Anna M. Mileo, Ataúlfo Martínez-Torres, Fabrizio Eusebi, and Ricardo Miledi PMCID: PMC122629 The single-channel properties of human acetylcholine α7 receptors are altered by fusing α7 to the green fluorescent protein Sergio Fucile, Eleonora Palma, Ataúlfo Martínez-Torres, Ricardo Miledi, and Fabrizio Eusebi PMCID: PMC122630 Somatic action potentials are sufficient for late-phase LTP-related cell signaling Serena M. Dudek and R. Douglas Fields PMCID: PMC122631 Ionic dependence of Ca2+ channel modulation by syntaxin 1A Ofer Wiser, Roy Cohen, and Daphne Atlas PMCID: PMC122632 Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis Shu-ichi Okamoto, Zhen Li, Chung Ju, Marion N. Schölzke, Emily Mathews, Jiankun Cui, Guy S. Salvesen, Ella Bossy-Wetzel, and Stuart A. Lipton PMCID: PMC122633 Voltage opens unopposed gap junction hemichannels formed by a connexin 32 mutant associated with X-linked Charcot-Marie-Tooth disease C. K. Abrams, M. V. L. Bennett, V. K. Verselis, and T. A. Bargiello PMCID: PMC122634 Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism Beatriz Morte, Jimena Manzano, Thomas Scanlan, Björn Vennström, and Juan Bernal PMCID: PMC122635 sgk, a primary glucocorticoid-induced gene, facilitates memory consolidation of spatial learning in rats Kuen J. Tsai, Shau K. Chen, Yun L. Ma, Wei L. Hsu, and Eminy H. Y. Lee PMCID: PMC122636 Disruption of estrogen receptor β gene impairs spatial learning in female mice Emilie F. Rissman, Amy L. Heck, Julie E. Leonard, Margaret A. Shupnik, and Jan-Åke Gustafsson PMCID: PMC122637 Induction of behavioral associative memory by stimulation of the nucleus basalis Dewey E. McLin, III, Alexandre A. Miasnikov, and Norman M. Weinberger PMCID: PMC122638 The vitelliform macular dystrophy protein defines a new family of chloride channels Hui Sun, Takashi Tsunenari, King-Wai Yau, and Jeremy Nathans PMCID: PMC122639 Notch receptor cleavage depends on but is not directly executed by presenilins Yoshihito Taniguchi, Helena Karlström, Johan Lundkvist, Tomohiko Mizutani, Akira Otaka, Monica Vestling, Alan Bernstein, Dorit Donoviel, Urban Lendahl, and Tasuku Honjo PMCID: PMC122640 Reelin function in neural stem cell biology H. M. Kim, T. Qu, V. Kriho, P. Lacor, N. Smalheiser, G. D. Pappas, A. Guidotti, E. Costa, and K. Sugaya PMCID: PMC122641 Updating of the visual representation in monkey striate and extrastriate cortex during saccades Kae Nakamura and Carol L. Colby PMCID: PMC122642 Frequency-dependent synchrony in locus ceruleus: Role of electrotonic coupling Veronica A. Alvarez, Carson C. Chow, Elisabeth J. Van Bockstaele, and John T. Williams PMCID: PMC122643 Glial protein S100B modulates long-term neuronal synaptic plasticity Hiroshi Nishiyama, Thomas Knöpfel, Shogo Endo, and Shigeyoshi Itohara PMCID: PMC122644 Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons Cristine Alves da Costa, Erwan Paitel, Mark P. Mattson, Robert Amson, Adam Telerman, Karine Ancolio, and Frédéric Checler PMCID: PMC122645 Learning to see the trees before the forest: Reversible deactivation of the superior colliculus during learning of local and global visual features Stephen G. Lomber PMCID: PMC122646 Pharmacology Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: Implications in atherosclerosis Tapan K. Mukherjee, Hillary Dinh, Gautam Chaudhuri, and Lauren Nathan PMCID: PMC122647 Physiology Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection K. Joseph Hurt, Biljana Musicki, Michael A. Palese, Julie K. Crone, Robyn E. Becker, John L. Moriarity, Solomon H. Snyder, and Arthur L. Burnett PMCID: PMC122648 Short day lengths augment stress-induced leukocyte trafficking and stress-induced enhancement of skin immune function Staci D. Bilbo, Firdaus S. Dhabhar, Kavitha Viswanathan, Alison Saul, Steven M. Yellon, and Randy J. Nelson PMCID: PMC122649 An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart Sebastian K. G. Maier, Ruth E. Westenbroek, Kenneth A. Schenkman, Eric O. Feigl, Todd Scheuer, and William A. Catterall PMCID: PMC122650 Plant Biology AtKC1, a silent Arabidopsis potassium channel α-subunit modulates root hair K+ influx Birgit Reintanz, Alexander Szyroki, Natalya Ivashikina, Peter Ache, Matthias Godde, Dirk Becker, Klaus Palme, and Rainer Hedrich PMCID: PMC122651 Evidence for in vivo modulation of chloroplast RNA stability by 3′-UTR homopolymeric tails in Chlamydomonas reinhardtii Yutaka Komine, Elise Kikis, Gadi Schuster, and David Stern PMCID: PMC122652 Functional asymmetry of photosystem II D1 and D2 peripheral chlorophyll mutants of Chlamydomonas reinhardtii Jun Wang, David Gosztola, Stuart V. Ruffle, Craig Hemann, Michael Seibert, Michael R. Wasielewski, Russ Hille, Terry L. Gustafson, and Richard T. Sayre PMCID: PMC122653 Hydrogen peroxide homeostasis: Activation of plant catalase by calcium/calmodulin T. Yang and B. W. Poovaiah PMCID: PMC122654 Intercellular trafficking of a KNOTTED1 green fluorescent protein fusion in the leaf and shoot meristem of Arabidopsis Jae Yean Kim, Zhuang Yuan, Michelle Cilia, Zainab Khalfan-Jagani, and David Jackson PMCID: PMC122655 Overexpression of a Na+/H+ antiporter confers salt tolerance on a freshwater cyanobacterium, making it capable of growth in sea water Rungaroon Waditee, Takashi Hibino, Tatsunosuke Nakamura, Aran Incharoensakdi, and Teruhiro Takabe PMCID: PMC122656 Psychology Integration of emotion and cognition in the lateral prefrontal cortex Jeremy R. Gray, Todd S. Braver, and Marcus E. Raichle PMCID: PMC122657 Fear recognition in the voice is modulated by unconsciously recognized facial expressions but not by unconsciously recognized affective pictures Beatrice de Gelder, Gilles Pourtois, and Lawrence Weiskrantz PMCID: PMC122658 Social Sciences Psychology The perceptual reality of synesthetic colors Thomas J. Palmeri, Randolph Blake, René Marois, Marci A. Flanery, and William Whetsell, Jr. PMCID: PMC122659 Corrections Proc Natl Acad Sci U S A. 2002 March 19; 99(6): 4132. doi: 10.1073/pnas.062024199.PMCID: PMC122523 Corrects: Paul G. Mermelstein, et al. Calmodulin priming: Nuclear translocation of a
calmodulin complex and the memory of prior
neuronal activity. Proc Natl Acad Sci U S A. 2001 December 18; 98(26): 15342–15347. Proc Natl Acad Sci U S A. 2002 March 19; 99(6): 4134. doi: 10.1073/pnas.072044999.PMCID: PMC122524 Corrects: Yinghui Mao, et al. Subnuclear distribution of topoisomerase I is linked to ongoing transcription and p53 status. Proc Natl Acad Sci U S A. 2002 February 5; 99(3): 1235–1240. |
