| | This journal provides immediate access to some articles. Commentaries Is knowing always feeling? Alan G. Sanfey and Jonathan D. Cohen PMCID: PMC534737 Postmenopausal osteoporosis, T cells, and immune dysfunction Steven L. Teitelbaum PMCID: PMC534741 Shifting paradigms: Herbivory and body size in lizards Laurie J. Vitt PMCID: PMC534748 Physical Sciences Applied Mathematics The organization of orientation and spatial frequency in primary visual cortex Lawrence Sirovich and Robert Uglesich PMCID: PMC534713 Chemistry From the Cover:
A small-molecule switch for Golgi sulfotransferases Christopher L. de Graffenried, Scott T. Laughlin, Jennifer J. Kohler, and Carolyn R. Bertozzi PMCID: PMC534710 Compound library development guided by protein structure similarity clustering and natural product structure Marcus A. Koch, Lars-Oliver Wittenberg, Sudipta Basu, Duraiswamy A. Jeyaraj, Eleni Gourzoulidou, Kerstin Reinecke, Alex Odermatt, and Herbert Waldmann PMCID: PMC534721 Synthesis of galmic: A nonpeptide galanin receptor agonist Susana Conde Ceide, Laurent Trembleau, Gebhard Haberhauer, Laszlo Somogyi, Xiaoying Lu, Tamas Bartfai, and Julius Rebek, Jr. PMCID: PMC534730 Recycling Frank: Spontaneous emergence of homochirality in noncatalytic systems Raphaël Plasson, Hugues Bersini, and Auguste Commeyras PMCID: PMC534711 Statistics Linkage analysis of ordinal traits for pedigree data Rui Feng, James F. Leckman, and Heping Zhang PMCID: PMC534720 Biological Sciences Applied Biological Sciences Evolution of new nonantibody proteins via iterative somatic hypermutation Lei Wang, W. Coyt Jackson, Paul A. Steinbach, and Roger Y. Tsien PMCID: PMC529417 Biochemistry Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex Steven L. Kazmirski, Marjetka Podobnik, Tanya F. Weitze, Mike O'Donnell, and John Kuriyan PMCID: PMC529418 Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel Sen Zhang, Alan Finkelstein, and R. John Collier PMCID: PMC534726 The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1 Wensheng Wang, Patrick Brandt, Marie L. Rossi, Laura Lindsey-Boltz, Vladimir Podust, Ellen Fanning, Aziz Sancar, and Robert A. Bambara PMCID: PMC534749 Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist Bogdan Z. Olenyuk, Guo-Jun Zhang, Jeffery M. Klco, Nicholas G. Nickols, William G. Kaelin, Jr., and Peter B. Dervan PMCID: PMC534742 On the mechanism and biology of cytochrome oxidase inhibition by nitric oxide Fernando Antunes, Alberto Boveris, and Enrique Cadenas PMCID: PMC534717 Biophysics Prediction of the structural motifs of sandwich proteins A. S. Fokas, I. M. Gelfand, and A. E. Kister PMCID: PMC534733 Running on water: Three-dimensional force generation by basilisk lizards S. Tonia Hsieh and George V. Lauder PMCID: PMC534722 Halogen bonds in biological molecules Pascal Auffinger, Franklin A. Hays, Eric Westhof, and P. Shing Ho PMCID: PMC529416 Cell Biology From the Cover:
Defective lysosomal exocytosis and plasma membrane repair in Chediak–Higashi/beige cells Chau Huynh, Doris Roth, Diane M. Ward, Jerry Kaplan, and Norma W. Andrews PMCID: PMC534728 Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland Manrico Morroni, Antonio Giordano, Maria Cristina Zingaretti, Romina Boiani, Rita De Matteis, Barbara B. Kahn, Enzo Nisoli, Cristina Tonello, Catalina Pisoschi, Michele M. Luchetti, Mariella Marelli, and Saverio Cinti PMCID: PMC534744 Sarcolipin retention in the endoplasmic reticulum depends on its C-terminal RSYQY sequence and its interaction with sarco(endo)plasmic Ca2+-ATPases Anthony O. Gramolini, Thomas Kislinger, Michio Asahi, Wenping Li, Andrew Emili, and David H. MacLennan PMCID: PMC534750 Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization Jennifer LeCouter, Constance Zlot, Max Tejada, Franklin Peale, and Napoleone Ferrara PMCID: PMC528996 Evolution From the Cover:
Recurrent evolution of herbivory in small, cold-climate lizards: Breaking the ecophysiological rules of reptilian herbivory Robert E. Espinoza, John J. Wiens, and C. Richard Tracy PMCID: PMC534712 Coding sequences of functioning human genes derived entirely from mobile element sequences Roy J. Britten PMCID: PMC534736 Genetics dsu functions in a MYO5A-independent pathway to suppress the coat color of dilute mice T. Norene O'Sullivan, Xufeng S. Wu, Rivka A. Rachel, Jiang-Dong Huang, Deborah A. Swing, Lydia E. Matesic, John A. Hammer, III, Neal G. Copeland, and Nancy A. Jenkins PMCID: PMC534743 Discovery of functional noncoding elements by digital analysis of chromatin structure Peter J. Sabo, Michael Hawrylycz, James C. Wallace, Richard Humbert, Man Yu, Anthony Shafer, Janelle Kawamoto, Robert Hall, Joshua Mack, Michael O. Dorschner, Michael McArthur, and John A. Stamatoyannopoulos PMCID: PMC534745 Changes in genomewide occupancy of core transcriptional regulators during heat stress Sara J. Zanton and B. Franklin Pugh PMCID: PMC534727 A gene encoding a putative FAD-dependent l-2-hydroxyglutarate dehydrogenase is mutated in l-2-hydroxyglutaric aciduria Rim Rzem, Maria Veiga-da-Cunha, Gaëtane Noël, Sophie Goffette, Marie-Cécile Nassogne, Brahim Tabarki, Christina Schöller, Thorsten Marquardt, Miikka Vikkula, and Emile Van Schaftingen PMCID: PMC534725 GC/AT-content spikes as genomic punctuation marks Lingang Zhang, Simon Kasif, Charles R. Cantor, and Natalia E. Broude PMCID: PMC534751 Differentiation-induced replication-timing changes are restricted to AT-rich/long interspersed nuclear element (LINE)-rich isochores Ichiro Hiratani, Amanda Leskovar, and David M. Gilbert PMCID: PMC534734 Immunology Solution structure of the CD3εδ ectodomain and comparison with CD3εγ as a basis for modeling T cell receptor topology and signaling Zhen-Yu J. Sun, Sun Taek Kim, Il Chul Kim, Amr Fahmy, Ellis L. Reinherz, and Gerhard Wagner PMCID: PMC534738 Human and murine inhibitory natural killer cell receptors transfer from natural killer cells to target cells Bruno Vanherberghen, Katja Andersson, Leo M. Carlin, Esther N. M. Nolte-`t Hoen, Geoffrey S. Williams, Petter Höglund, and Daniel M. Davis PMCID: PMC534731 Activation of the complement system generates antibacterial peptides Emma Andersson Nordahl, Victoria Rydengård, Patrik Nyberg, D. Patric Nitsche, Matthias Mörgelin, Martin Malmsten, Lars Björck, and Artur Schmidtchen PMCID: PMC534732 The molecular program induced in T cells undergoing homeostatic proliferation Ananda W. Goldrath, C. John Luckey, Richard Park, Christophe Benoist, and Diane Mathis PMCID: PMC534746 Medical Sciences Transplanted human bone marrow contributes to vascular endothelium Shuguang Jiang, Luke Walker, Michael Afentoulis, Daniel A. Anderson, Linda Jauron-Mills, Christopher L. Corless, and William H. Fleming PMCID: PMC534718 SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells Manu Kohli, Jian Yu, Craig Seaman, Alberto Bardelli, Kenneth W. Kinzler, Bert Vogelstein, Christoph Lengauer, and Lin Zhang PMCID: PMC534714 From the Cover:
Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations Heidi Erlandsen, Angel L. Pey, Alejandra Gámez, Belén Pérez, Lourdes R. Desviat, Cristina Aguado, Richard Koch, Sankar Surendran, Stephen Tyring, Reuben Matalon, Charles R. Scriver, Magdalena Ugarte, Aurora Martínez, and Raymond C. Stevens PMCID: PMC534739 Bioluminescent imaging of a marking transgene and correction of Fabry mice by neonatal injection of recombinant lentiviral vectors Makoto Yoshimitsu, Takeya Sato, Kesheng Tao, Jagdeep S. Walia, Vanessa I. Rasaiah, Gillian T. Sleep, Gary J. Murray, Armando G. Poeppl, John Underwood, Lori West, Roscoe O. Brady, and Jeffrey A. Medin PMCID: PMC534735 Dynamical resonance can account for seasonality of influenza epidemics Jonathan Dushoff, Joshua B. Plotkin, Simon A. Levin, and David J. D. Earn PMCID: PMC534740 Microbiology Interspecies communication in Streptococcus gordonii–Veillonella atypica biofilms: Signaling in flow conditions requires juxtaposition Paul G. Egland, Robert J. Palmer, Jr., and Paul E. Kolenbrander PMCID: PMC534724 From the Cover:
Metastability of Helicobacter pylori bab adhesin genes and dynamics in Lewis b antigen binding Anna Bäckström, Carina Lundberg, Dangeruta Kersulyte, Douglas E. Berg, Thomas Borén, and Anna Arnqvist PMCID: PMC534723 Anaerobic growth of Methanosarcina acetivorans C2A on carbon monoxide: An unusual way of life for a methanogenic archaeon Michael Rother and William W. Metcalf PMCID: PMC529327 Neuroscience Experimental test of the birdsong error-correction model Anthony Leonardo PMCID: PMC534752 The organization of orientation and spatial frequency in primary visual cortex Lawrence Sirovich and Robert Uglesich PMCID: PMC534713 Perceptual deficits in patients with impaired recognition of biological motion after temporal lobe lesions Lucia M. Vaina and Charles G. Gross PMCID: PMC534747 Ca2+ activity at GABAB receptors constitutively promotes metabotropic glutamate signaling in the absence of GABA Toshihide Tabata, Kenji Araishi, Kouichi Hashimoto, Yuki Hashimotodani, Herman van der Putten, Bernhard Bettler, and Masanobu Kano PMCID: PMC529326 Pharmacology Differential nitros(yl)ation of blood and tissue constituents during glyceryl trinitrate biotransformation in vivo David R. Janero, Nathan S. Bryan, Fumito Saijo, Vijay Dhawan, David J. Schwalb, Michael C. Warren, and Martin Feelisch PMCID: PMC534729 Function recovery after chemobleaching (FRAC): Evidence for activity silent membrane receptors on cell surface Haiyan Sun, Sojin Shikano, Qiaojie Xiong, and Min Li PMCID: PMC534715 Physiology Coping with cold: An integrative, multitissue analysis of the transcriptome of a poikilothermic vertebrate Andrew Y. Gracey, E. Jane Fraser, Weizhong Li, Yongxiang Fang, Ruth R. Taylor, Jane Rogers, Andrew Brass, and Andrew R. Cossins PMCID: PMC534716 Plant Biology A highly specific l-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis William A. Laing, Sean Bulley, Michele Wright, Janine Cooney, Dwayne Jensen, Di Barraclough, and Elspeth MacRae PMCID: PMC534719 Correction Proc Natl Acad Sci U S A. 2004 November 30; 101(48): 16982. Published online 2004 November 10. doi: 10.1073/pnas.0408040101.PMCID: PMC534753 Corrects: Chih-Hung Lai, et al. Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons. Proc Natl Acad Sci U S A. 2004 November 2; 101(44): 15676–15681. |
