| | This journal provides immediate access to some articles. Inaugural Article Structure, dynamics, and evolution of centromeric nucleosomes Yamini Dalal, Takehito Furuyama, Danielle Vermaak, and Steven Henikoff PMCID: PMC1993840 This Week in PNAS Proc Natl Acad Sci U S A. 2007 October 9; 104(41): 15967–15968. doi: 10.1073/iti4107104.PMCID: PMC2042143 Editorial Sustainable health: A new dimension of sustainability science Barry R. Bloom PMCID: PMC2042144 Commentaries Collective cell migration patterns: Follow the leader Nir S. Gov PMCID: PMC2042145 Locust plagues, climate variation, and the rhythms of nature Mauricio Lima PMCID: PMC2042146 Physical Sciences Applied Mathematics The narrow escape problem for diffusion in cellular microdomains Z. Schuss, A. Singer, and D. Holcman PMCID: PMC1994903 Applied Physical Sciences An interpretation of fluctuations in enzyme catalysis rate, spectral diffusion, and radiative component of lifetimes in terms of electric field fluctuations Meher K. Prakash and R. A. Marcus PMCID: PMC2042148 From the Cover:
Collective migration of an epithelial monolayer in response to a model wound M. Poujade, E. Grasland-Mongrain, A. Hertzog, J. Jouanneau, P. Chavrier, B. Ladoux, A. Buguin, and P. Silberzan PMCID: PMC2042149 Control of electrostatic interactions between F-actin and genetically modified lysozyme in aqueous media Lori K. Sanders, Wujing Xian, Camilo Guáqueta, Michael J. Strohman, Chuck R. Vrasich, Erik Luijten, and Gerard C. L. Wong PMCID: PMC2042150 Chemistry Adaptations of guest and host in expanded self-assembled capsules Dariush Ajami and Julius Rebek, Jr. PMCID: PMC2042151 Environmental Sciences Weak response of oceanic dimethylsulfide to upper mixing shoaling induced by global warming S. M. Vallina, R. Simó, and M. Manizza PMCID: PMC2042152 Geology Supermodeled sabercat, predatory behavior in Smilodon fatalis revealed by high-resolution 3D computer simulation Colin R. McHenry, Stephen Wroe, Philip D. Clausen, Karen Moreno, and Eleanor Cunningham PMCID: PMC2042153 Geophysics Evidence for an extraterrestrial impact 12,900 years ago that contributed to the megafaunal extinctions and the Younger Dryas cooling R. B. Firestone, A. West, J. P. Kennett, L. Becker, T. E. Bunch, Z. S. Revay, P. H. Schultz, T. Belgya, D. J. Kennett, J. M. Erlandson, O. J. Dickenson, A. C. Goodyear, R. S. Harris, G. A. Howard, J. B. Kloosterman, P. Lechler, P. A. Mayewski, J. Montgomery, R. Poreda, T. Darrah, S. S. Que Hee, A. R. Smith, A. Stich, W. Topping, J. H. Wittke, and W. S. Wolbach PMCID: PMC1994902 Physics A mechanobiochemical mechanism for monooriented chromosome oscillation in mitosis Jian Liu, Arshad Desai, José N. Onuchic, and Terence Hwa PMCID: PMC2042169 Biological Sciences Applied Biological Sciences Sticky overhangs enhance siRNA-mediated gene silencing Anne-Laure Bolcato-Bellemin, Marie-Elise Bonnet, Gaëlle Creusat, Patrick Erbacher, and Jean-Paul Behr PMCID: PMC2042160 Deletion mutations in N-terminal α1 helix render heat labile enterotoxin B subunit susceptible to degradation Pankaj V. Alone, Gunjan Malik, Anuja Krishnan, and Lalit C. Garg PMCID: PMC2042161 Biochemistry Structure, dynamics, and evolution of centromeric nucleosomes Yamini Dalal, Takehito Furuyama, Danielle Vermaak, and Steven Henikoff PMCID: PMC1993840 TFIIS elongation factor and Mediator act in conjunction during transcription initiation in vivo Benjamin Guglielmi, Julie Soutourina, Cyril Esnault, and Michel Werner PMCID: PMC2042162 The transcription elongation factor TFIIS is a component of RNA polymerase II preinitiation complexes Bong Kim, Alexey I. Nesvizhskii, P. Geetha Rani, Steven Hahn, Ruedi Aebersold, and Jeffrey A. Ranish PMCID: PMC2042163 A surface on the androgen receptor that allosterically regulates coactivator binding Eva Estébanez-Perpiñá, Alexander A. Arnold, Phuong Nguyen, Edson Delgado Rodrigues, Ellena Mar, Raynard Bateman, Peter Pallai, Kevan M. Shokat, John D. Baxter, R. Kiplin Guy, Paul Webb, and Robert J. Fletterick PMCID: PMC1999396 Disease-associated mutant α-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity Astrid Weins, Johannes S. Schlondorff, Fumihiko Nakamura, Bradley M. Denker, John H. Hartwig, Thomas P. Stossel, and Martin R. Pollak PMCID: PMC2042165 Chymotryptic specificity determinants in the 1.0 Å structure of the zinc-inhibited human tissue kallikrein 7 Mekdes Debela, Petra Hess, Viktor Magdolen, Norman M. Schechter, Thomas Steiner, Robert Huber, Wolfram Bode, and Peter Goettig PMCID: PMC2042166 Guanine riboswitch variants from Mesoplasma florum selectively recognize 2′-deoxyguanosine Jane N. Kim, Adam Roth, and Ronald R. Breaker PMCID: PMC1999398 Biophysics An interpretation of fluctuations in enzyme catalysis rate, spectral diffusion, and radiative component of lifetimes in terms of electric field fluctuations Meher K. Prakash and R. A. Marcus PMCID: PMC2042148 The narrow escape problem for diffusion in cellular microdomains Z. Schuss, A. Singer, and D. Holcman PMCID: PMC1994903 A mechanobiochemical mechanism for monooriented chromosome oscillation in mitosis Jian Liu, Arshad Desai, José N. Onuchic, and Terence Hwa PMCID: PMC2042169 Z-ring force and cell shape during division in rod-like bacteria Ganhui Lan, Charles W. Wolgemuth, and Sean X. Sun PMCID: PMC2042170 Neuroglobin dynamics observed with ultrafast 2D-IR vibrational echo spectroscopy Haruto Ishikawa, Ilya J. Finkelstein, Seongheun Kim, Kyungwon Kwak, Jean K. Chung, Keisuke Wakasugi, Aaron M. Massari, and Michael D. Fayer PMCID: PMC2042171 Toxofilin from Toxoplasma gondii forms a ternary complex with an antiparallel actin dimer Sung Haeng Lee, David B. Hayes, Grzegorz Rebowski, Isabelle Tardieux, and Roberto Dominguez PMCID: PMC2042172 Force fluctuations and polymerization dynamics of intracellular microtubules Clifford P. Brangwynne, F. C. MacKintosh, and David A. Weitz PMCID: PMC2042173 The coordination of cyclic microtubule association/dissociation and tail swing of cytoplasmic dynein Kenji Imamula, Takahide Kon, Reiko Ohkura, and Kazuo Sutoh PMCID: PMC1999400 Structure of outer membrane protein G by solution NMR spectroscopy Binyong Liang and Lukas K. Tamm PMCID: PMC2042175 From the Cover:
Kinetic insulation as an effective mechanism for achieving pathway specificity in intracellular signaling networks Marcelo Behar, Henrik G. Dohlman, and Timothy C. Elston PMCID: PMC2042176 Protein stability imposes limits on organism complexity and speed of molecular evolution Konstantin B. Zeldovich, Peiqiu Chen, and Eugene I. Shakhnovich PMCID: PMC2042177 Cell Biology From the Cover:
Collective migration of an epithelial monolayer in response to a model wound M. Poujade, E. Grasland-Mongrain, A. Hertzog, J. Jouanneau, P. Chavrier, B. Ladoux, A. Buguin, and P. Silberzan PMCID: PMC2042149 Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance Jiangbing Zhou, Julia Wulfkuhle, Hao Zhang, Peihua Gu, Yanqin Yang, Jianghong Deng, Joseph B. Margolick, Lance A. Liotta, Emanuel Petricoin, III, and Ying Zhang PMCID: PMC2042178 Modulation of LMP1 protein expression by EBV-encoded microRNAs Angela Kwok Fung Lo, Ka Fai To, Kwok Wai Lo, Raymond Wai Ming Lung, Jan Wai Ying Hui, Gangling Liao, and S. Diane Hayward PMCID: PMC2042179 Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development Meritxell Gironella, Mylène Seux, Min-Jue Xie, Carla Cano, Richard Tomasini, Julien Gommeaux, Stephane Garcia, Jonathan Nowak, Man Lung Yeung, Kuan-Teh Jeang, Amandine Chaix, Ladan Fazli, Yoshiharu Motoo, Qing Wang, Palma Rocchi, Antonio Russo, Martin Gleave, Jean-Charles Dagorn, Juan L. Iovanna, Alice Carrier, Marie-Josèphe Pébusque, and Nelson J. Dusetti PMCID: PMC2042180 Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages John H. Evans and Joseph J. Falke PMCID: PMC2042181 Developmental Biology Microtubule-based nuclear movement occurs independently of centrosome positioning in migrating neurons Hiroki Umeshima, Tomoo Hirano, and Mineko Kengaku PMCID: PMC2000450 Ecology From the Cover:
Thousand-year-long Chinese time series reveals climatic forcing of decadal locust dynamics Leif Christian Stige, Kung-Sik Chan, Zhibin Zhang, David Frank, and Nils C. Stenseth PMCID: PMC2042183 Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina Ricardo E. Gürtler, Uriel Kitron, M. Carla Cecere, Elsa L. Segura, and Joel E. Cohen PMCID: PMC2042184 Environmental Sciences Tracing the effects of the Little Ice Age in the tropical lowlands of eastern Mesoamerica Ma. del Socorro Lozano-García, Margarita Caballero, Beatriz Ortega, Alejandro Rodríguez, and Susana Sosa PMCID: PMC2000453 Toxins in transgenic crop byproducts may affect headwater stream ecosystems E. J. Rosi-Marshall, J. L. Tank, T. V. Royer, M. R. Whiles, M. Evans-White, C. Chambers, N. A. Griffiths, J. Pokelsek, and M. L. Stephen PMCID: PMC2042185 Evolution Gel-forming mucins appeared early in metazoan evolution Tiange Lang, Gunnar C. Hansson, and Tore Samuelsson PMCID: PMC2042186 Genetics A genome-wide analysis in Anopheles gambiae mosquitoes reveals 46 male accessory gland genes, possible modulators of female behavior Tania Dottorini, Lietta Nicolaides, Hilary Ranson, David W. Rogers, Andrea Crisanti, and Flaminia Catteruccia PMCID: PMC2042187 From the Cover:
Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial Hannah V. Siddle, Alexandre Kreiss, Mark D. B. Eldridge, Erin Noonan, Candice J. Clarke, Stephen Pyecroft, Gregory M. Woods, and Katherine Belov PMCID: PMC1999395 A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration Atsuhiro Kanda, Wei Chen, Mohammad Othman, Kari E. H. Branham, Matthew Brooks, Ritu Khanna, Shirley He, Robert Lyons, Gonçalo R. Abecasis, and Anand Swaroop PMCID: PMC1987388 Immunology Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype Alexandre Harari, Cristina Cellerai, Felicitas Bellutti Enders, Josef Köstler, Laura Codarri, Gonzalo Tapia, Onur Boyman, Erika Castro, Silvana Gaudieri, Ian James, Mina John, Ralf Wagner, Simon Mallal, and Giuseppe Pantaleo PMCID: PMC1999394 Activin A is a critical component of the inflammatory response, and its binding protein, follistatin, reduces mortality in endotoxemia Kristian L. Jones, Ashley Mansell, Shane Patella, Bernadette J. Scott, Mark P. Hedger, David M. de Kretser, and David J. Phillips PMCID: PMC2042191 Transcription factor expression in lipopolysaccharide-activated peripheral-blood-derived mononuclear cells Jared C. Roach, Kelly D. Smith, Katie L. Strobe, Stephanie M. Nissen, Christian D. Haudenschild, Daixing Zhou, Thomas J. Vasicek, G. A. Held, Gustavo A. Stolovitzky, Leroy E. Hood, and Alan Aderem PMCID: PMC2042192 Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes Anita Schwegmann, Reto Guler, Antony J. Cutler, Berenice Arendse, William G. C. Horsnell, Alexandra Flemming, Andreas H. Kottmann, Gregory Ryan, Winston Hide, Michael Leitges, Cathal Seoighe, and Frank Brombacher PMCID: PMC2000452 MAP kinase phosphatase activity sets the threshold for thymocyte positive selection Matthew L. Bettini and Gilbert J. Kersh PMCID: PMC2042194 Medical Sciences Educational status and cardiovascular risk profile in Indians K. Srinath Reddy, Dorairaj Prabhakaran, Panniyammakal Jeemon, K. R. Thankappan, Prashant Joshi, Vivek Chaturvedi, Lakshmy Ramakrishnan, and Farooque Ahmed PMCID: PMC2042195 Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus Daniel X. Johansson, Cécile Voisset, Alexander W. Tarr, Mie Aung, Jonathan K. Ball, Jean Dubuisson, and Mats A. A. Persson PMCID: PMC2042196 Notch signaling in vascular smooth muscle cells is required to pattern the cerebral vasculature Aaron Proweller, Alex C. Wright, Debra Horng, Lan Cheng, Min Min Lu, John J. Lepore, Warren S. Pear, and Michael S. Parmacek PMCID: PMC2042197 Plasma sodium stiffens vascular endothelium and reduces nitric oxide release Hans Oberleithner, Christoph Riethmüller, Hermann Schillers, Graham A. MacGregor, Hugh E. de Wardener, and Martin Hausberg PMCID: PMC1999397 Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein Ke Lan, Subhash C. Verma, Masanao Murakami, Bharat Bajaj, Rajeev Kaul, and Erle S. Robertson PMCID: PMC1997218 Microbiology Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain Kelly A. Gangwer, Darren J. Mushrush, Devin L. Stauff, Ben Spiller, Mark S. McClain, Timothy L. Cover, and D. Borden Lacy PMCID: PMC2042200 Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq J. W. Wilson, C. M. Ott, K. Höner zu Bentrup, R. Ramamurthy, L. Quick, S. Porwollik, P. Cheng, M. McClelland, G. Tsaprailis, T. Radabaugh, A. Hunt, D. Fernandez, E. Richter, M. Shah, M. Kilcoyne, L. Joshi, M. Nelman-Gonzalez, S. Hing, M. Parra, P. Dumars, K. Norwood, R. Bober, J. Devich, A. Ruggles, C. Goulart, M. Rupert, L. Stodieck, P. Stafford, L. Catella, M. J. Schurr, K. Buchanan, L. Morici, J. McCracken, P. Allen, C. Baker-Coleman, T. Hammond, J. Vogel, R. Nelson, D. L. Pierson, H. M. Stefanyshyn-Piper, and C. A. Nickerson PMCID: PMC2042201 Stimulus-dependent differential regulation in the Escherichia coli PhoQ–PhoP system Tim Miyashiro and Mark Goulian PMCID: PMC2042202 Neuroscience Dissociating speech perception and comprehension at reduced levels of awareness Matthew H. Davis, Martin R. Coleman, Anthony R. Absalom, Jennifer M. Rodd, Ingrid S. Johnsrude, Basil F. Matta, Adrian M. Owen, and David K. Menon PMCID: PMC2042157 Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning Michael J. Frank, Ahmed A. Moustafa, Heather M. Haughey, Tim Curran, and Kent E. Hutchison PMCID: PMC2042203 Dentate gyrus-specific manipulation of β-Ca2+/calmodulin-dependent kinase II disrupts memory consolidation Min H. Cho, Xiaohua Cao, Deheng Wang, and Joe Z. Tsien PMCID: PMC2042204 TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations Wen-Li Wei, Hong-Shuo Sun, Michelle E. Olah, Xiujun Sun, Elzbieta Czerwinska, Waldemar Czerwinski, Yasuo Mori, Beverley A. Orser, Zhi-Gang Xiong, Michael F. Jackson, Michael Tymianski, and John F. MacDonald PMCID: PMC2042205 Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death Sung-Wuk Jang, Masashi Okada, Iqbal Sayeed, Ge Xiao, Donald Stein, Peng Jin, and Keqiang Ye PMCID: PMC2042206 Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens Alexandra Jean, Grégory Conductier, Christine Manrique, Constantin Bouras, Philippe Berta, René Hen, Yves Charnay, Joël Bockaert, and Valérie Compan PMCID: PMC2042207 Time course and calcium dependence of transmitter release at a single ribbon synapse Juan D. Goutman and Elisabeth Glowatzki PMCID: PMC2042208 α2-Chimaerin interacts with EphA4 and regulates EphA4-dependent growth cone collapse Lei Shi, Wing-Yu Fu, Kwok-Wang Hung, Cassandra Porchetta, Christine Hall, Amy K. Y. Fu, and Nancy Y. Ip PMCID: PMC2042209 Modeling a layer 4-to-layer 2/3 module of a single column in rat neocortex: Interweaving in vitro and in vivo experimental observations Leora Sarid, Randy Bruno, Bert Sakmann, Idan Segev, and Dirk Feldmeyer PMCID: PMC2000451 β-Nicotinamide adenine dinucleotide is an inhibitory neurotransmitter in visceral smooth muscle Violeta N. Mutafova-Yambolieva, Sung Jin Hwang, Xuemei Hao, Hui Chen, Michael X. Zhu, Jackie D. Wood, Sean M. Ward, and Kenton M. Sanders PMCID: PMC2042211 Physiology Chimeric constructs endow the human CFTR Cl− channel with the gating behavior of murine CFTR Toby S. Scott-Ward, Zhiwei Cai, Elizabeth S. Dawson, Ann Doherty, Ana Carina Da Paula, Heather Davidson, David J. Porteous, Brandon J. Wainwright, Margarida D. Amaral, David N. Sheppard, and A. Christopher Boyd PMCID: PMC2042212 Plant Biology From the Cover:
Genetic analysis reveals functional redundancy and the major target genes of the Arabidopsis miR159 family Robert S. Allen, Junyan Li, Melissa I. Stahle, Aurélie Dubroué, Frank Gubler, and Anthony A. Millar PMCID: PMC2042213 ATPase activity of KaiC determines the basic timing for circadian clock of cyanobacteria Kazuki Terauchi, Yohko Kitayama, Taeko Nishiwaki, Kumiko Miwa, Yoriko Murayama, Tokitaka Oyama, and Takao Kondo PMCID: PMC2042214 Psychology Impaired familiarity with preserved recollection after anterior temporal-lobe resection that spares the hippocampus Ben Bowles, Carina Crupi, Seyed M. Mirsattari, Susan E. Pigott, Andrew G. Parrent, Jens C. Pruessner, Andrew P. Yonelinas, and Stefan Köhler PMCID: PMC1995093 Social Sciences Anthropology Coevolution of languages and genes on the island of Sumba, eastern Indonesia J. Stephen Lansing, Murray P. Cox, Sean S. Downey, Brandon M. Gabler, Brian Hallmark, Tatiana M. Karafet, Peter Norquest, John W. Schoenfelder, Herawati Sudoyo, Joseph C. Watkins, and Michael F. Hammer PMCID: PMC2042155 Psychology Native language governs interpretation of salient speech sound differences at 18 months Christiane Dietrich, Daniel Swingley, and Janet F. Werker PMCID: PMC1999399 Dissociating speech perception and comprehension at reduced levels of awareness Matthew H. Davis, Martin R. Coleman, Anthony R. Absalom, Jennifer M. Rodd, Ingrid S. Johnsrude, Basil F. Matta, Adrian M. Owen, and David K. Menon PMCID: PMC2042157 Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning Michael J. Frank, Ahmed A. Moustafa, Heather M. Haughey, Tim Curran, and Kent E. Hutchison PMCID: PMC2042203 Sustainability Science Bridges to sustainable tropical health Burton H. Singer and Marcia Caldas de Castro PMCID: PMC2042158 Mortality traps and the dynamics of health transitions David E. Bloom and David Canning PMCID: PMC2042159 Sustainable vector control and management of Chagas disease in the Gran Chaco, Argentina Ricardo E. Gürtler, Uriel Kitron, M. Carla Cecere, Elsa L. Segura, and Joel E. Cohen PMCID: PMC2042184 Educational status and cardiovascular risk profile in Indians K. Srinath Reddy, Dorairaj Prabhakaran, Panniyammakal Jeemon, K. R. Thankappan, Prashant Joshi, Vivek Chaturvedi, Lakshmy Ramakrishnan, and Farooque Ahmed PMCID: PMC2042195 Corrections Correction for Scherr et al., Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis PMCID: PMC2042216 Corrects: Nicole Scherr, et al. From the Cover:
Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2007 July 17; 104(29): 12151–12156. Correction for Uenoyama and Miyata, Gliding ghosts of Mycoplasma mobile PMCID: PMC2042217 Corrects: Atsuko Uenoyama, et al. From the Cover:
Gliding ghosts of Mycoplasma mobile. Proc Natl Acad Sci U S A. 2005 September 6; 102(36): 12754–12758. Correction for Xi et al., Lsh controls Hox gene silencing during development PMCID: PMC2042218 Corrects: Sichuan Xi, et al. Lsh controls Hox gene silencing during development. Proc Natl Acad Sci U S A. 2007 September 4; 104(36): 14366–14371. |
