| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 687–688. doi: 10.1073/iti0307104.PMCID: PMC1783372 Commentaries Nonpeptidic glucagon-like peptide 1 receptor agonists: A magic bullet for diabetes? K. G. Murphy and S. R. Bloom Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 689–690. Published online 2007 January 9. doi: 10.1073/pnas.0610679104.PMCID: PMC1783373 Deception point: Peptidoglycan modification as a means of immune evasion Jennifer L. Bishop, Erin C. Boyle, and B. Brett Finlay Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 691–692. Published online 2007 January 12. doi: 10.1073/pnas.0611133104.PMCID: PMC1783374 Profile Profile of J. Woodland Hastings Tinsley H. Davis Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 693–695. Published online 2007 January 10. doi: 10.1073/pnas.0610519104.PMCID: PMC1783375 Physical Sciences Applied Mathematics Noise can play an organizing role for the recurrent dynamics in excitable media Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 702–707. Published online 2007 January 8. doi: 10.1073/pnas.0607433104.PMCID: PMC1783377 Improved evolutionary optimization from genetically adaptive multimethod search Jasper A. Vrugt and Bruce A. Robinson Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 708–711. Published online 2007 January 10. doi: 10.1073/pnas.0610471104.PMCID: PMC1766340 Chemistry DNA folding and melting observed in real time redefine the energy landscape Hairong Ma, Chaozhi Wan, Aiguo Wu, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 712–716. Published online 2007 January 10. doi: 10.1073/pnas.0610028104.PMCID: PMC1766338 A precise packing sequence for self-assembled convex structures Ting Chen, Zhenli Zhang, and Sharon C. Glotzer Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 717–722. Published online 2007 January 10. doi: 10.1073/pnas.0604239104.PMCID: PMC1783380 Photoselected electron transfer pathways in DNA photolyase Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 802–807. Published online 2007 January 5. doi: 10.1073/pnas.0605319104.PMCID: PMC1783394 Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 808–813. Published online 2007 January 4. doi: 10.1073/pnas.0610202104.PMCID: PMC1783395 Computer Sciences A consensus view of protein dynamics Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 796–801. Published online 2007 January 10. doi: 10.1073/pnas.0605534104.PMCID: PMC1783393 Mathematics On positivity of certain systems of partial differential equations Alberto Parmeggiani Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 723–726. Published online 2007 January 9. doi: 10.1073/pnas.0609949104.PMCID: PMC1783381 Physics Characterization and application of single fluorescent nanodiamonds as cellular biomarkers Chi-Cheng Fu, Hsu-Yang Lee, Kowa Chen, Tsong-Shin Lim, Hsiao-Yun Wu, Po-Keng Lin, Pei-Kuen Wei, Pei-Hsi Tsao, Huan-Cheng Chang, and Wunshain Fann Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 727–732. Published online 2007 January 9. doi: 10.1073/pnas.0605409104.PMCID: PMC1783382 Effects of lengthscales and attractions on the collapse of hydrophobic polymers in water Manoj V. Athawale, Gaurav Goel, Tuhin Ghosh, Thomas M. Truskett, and Shekhar Garde Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 733–738. Published online 2007 January 10. doi: 10.1073/pnas.0605139104.PMCID: PMC1766333 Biological Sciences Anthropology Freshly excavated fossil bones are best for amplification of ancient DNA Mélanie Pruvost, Reinhard Schwarz, Virginia Bessa Correia, Sophie Champlot, Séverine Braguier, Nicolas Morel, Yolanda Fernandez-Jalvo, Thierry Grange, and Eva-Maria Geigl Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 739–744. Published online 2007 January 8. doi: 10.1073/pnas.0610257104.PMCID: PMC1783384 Biochemistry The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis M. Joanne Lemieux, Sarah J. Fischer, Maia M. Cherney, Katherine S. Bateman, and Michael N. G. James Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 750–754. Published online 2007 January 8. doi: 10.1073/pnas.0609981104.PMCID: PMC1783385 Alleviation of 1,N6-ethanoadenine genotoxicity by the Escherichia coli adaptive response protein AlkB Lauren E. Frick, James C. Delaney, Cintyu Wong, Catherine L. Drennan, and John M. Essigmann Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 755–760. Published online 2007 January 9. doi: 10.1073/pnas.0607377104.PMCID: PMC1783386 Biophysics Noise can play an organizing role for the recurrent dynamics in excitable media Cyrill B. Muratov, Eric Vanden-Eijnden, and Weinan E Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 702–707. Published online 2007 January 8. doi: 10.1073/pnas.0607433104.PMCID: PMC1783377 Flat and sigmoidally curved contact zones in vesicle–vesicle adhesion P. Ziherl and S. Svetina Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 761–765. Published online 2007 January 10. doi: 10.1073/pnas.0607633104.PMCID: PMC1766337 From the Cover: Neutron scattering reveals extremely slow cell water in a Dead Sea organism Moeava Tehei, Bruno Franzetti, Kathleen Wood, Frank Gabel, Elisa Fabiani, Marion Jasnin, Michaela Zamponi, Dieter Oesterhelt, Giuseppe Zaccai, Margaret Ginzburg, and Ben-Zion Ginzburg Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 766–771. Published online 2007 January 10. doi: 10.1073/pnas.0601639104.PMCID: PMC1783388 The power stroke of myosin VI and the basis of reverse directionality Zev Bryant, David Altman, and James A. Spudich Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 772–777. Published online 2006 December 20. doi: 10.1073/pnas.0610144104.PMCID: PMC1713167 The unique insert at the end of the myosin VI motor is the sole determinant of directionality Hyokeun Park, Anna Li, Li-Qiong Chen, Anne Houdusse, Paul R. Selvin, and H. Lee Sweeney Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 778–783. Published online 2007 January 9. doi: 10.1073/pnas.0610066104.PMCID: PMC1764864 Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain Kae-Jung Hwang, Fatemeh Mahmoodian, James A. Ferretti, Edward D. Korn, and James M. Gruschus Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 784–789. Published online 2007 January 10. doi: 10.1073/pnas.0610231104.PMCID: PMC1783391 Structure of the light-harvesting bacteriochlorophyll c assembly in chlorosomes from Chlorobium limicola determined by solid-state NMR Ayako Egawa, Toshimichi Fujiwara, Tadashi Mizoguchi, Yoshinori Kakitani, Yasushi Koyama, and Hideo Akutsu Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 790–795. Published online 2007 January 10. doi: 10.1073/pnas.0605911104.PMCID: PMC1783392 A consensus view of protein dynamics Manuel Rueda, Carles Ferrer-Costa, Tim Meyer, Alberto Pérez, Jordi Camps, Adam Hospital, Josep Lluis Gelpí, and Modesto Orozco Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 796–801. Published online 2007 January 10. doi: 10.1073/pnas.0605534104.PMCID: PMC1783393 Photoselected electron transfer pathways in DNA photolyase Tatiana R. Prytkova, David N. Beratan, and Spiros S. Skourtis Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 802–807. Published online 2007 January 5. doi: 10.1073/pnas.0605319104.PMCID: PMC1783394 Motifs for molecular recognition exploiting hydrophobic enclosure in protein–ligand binding Tom Young, Robert Abel, Byungchan Kim, Bruce J. Berne, and Richard A. Friesner Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 808–813. Published online 2007 January 4. doi: 10.1073/pnas.0610202104.PMCID: PMC1783395 A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol Pierre Aller, Mark A. Rould, Matthew Hogg, Susan S. Wallace, and Sylvie Doublié Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 814–818. Published online 2007 January 8. doi: 10.1073/pnas.0606648104.PMCID: PMC1783396 Cell Biology Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase Bin Zheng and Lewis C. Cantley Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 819–822. Published online 2007 January 4. doi: 10.1073/pnas.0610157104.PMCID: PMC1783397 Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype Nienwen Chow, Robert D. Bell, Rashid Deane, Jeffrey W. Streb, Jiyuan Chen, Andrew Brooks, William Van Nostrand, Joseph M. Miano, and Berislav V. Zlokovic Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 823–828. Published online 2007 January 10. doi: 10.1073/pnas.0608251104.PMCID: PMC1783398 Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex Qinghong Zhang, Su-Yan Wang, Capucine Fleuriel, Dominique Leprince, Jonathan V. Rocheleau, David W. Piston, and Richard H. Goodman Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 829–833. Published online 2007 January 9. doi: 10.1073/pnas.0610590104.PMCID: PMC1783399 Developmental Biology Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126) Caroline Schmitz, Parag Kinge, and Harald Hutter Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 834–839. Published online 2007 January 9. doi: 10.1073/pnas.0510527104.PMCID: PMC1783400 The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity John E. Pimanda, Ian J. Donaldson, Marella F. T. R. de Bruijn, Sarah Kinston, Kathy Knezevic, Liz Huckle, Sandie Piltz, Josette-Renée Landry, Anthony R. Green, David Tannahill, and Berthold Göttgens Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 840–845. Published online 2007 January 9. doi: 10.1073/pnas.0607196104.PMCID: PMC1783401 Baf60c is a nuclear Notch signaling component required for the establishment of left–right asymmetry Jun K. Takeuchi, Heiko Lickert, Brent W. Bisgrove, Xin Sun, Masamichi Yamamoto, Kallayanee Chawengsaksophak, Hiroshi Hamada, H. Joseph Yost, Janet Rossant, and Benoit G. Bruneau Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 846–851. Published online 2007 January 8. doi: 10.1073/pnas.0608118104.PMCID: PMC1783402 Polycomb-like genes are necessary for specification of dopaminergic and serotonergic neurons in Caenorhabditis elegans Yong Yang, Yinyan Sun, Xin Luo, Yuxia Zhang, Yaoyao Chen, E. Tian, Robyn Lints, and Hong Zhang Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 852–857. Published online 2007 January 10. doi: 10.1073/pnas.0610261104.PMCID: PMC1783403 Ecology Smelling home can prevent dispersal of reef fish larvae Gabriele Gerlach, Jelle Atema, Michael J. Kingsford, Kerry P. Black, and Vanessa Miller-Sims Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 858–863. Published online 2007 January 9. doi: 10.1073/pnas.0606777104.PMCID: PMC1783404 Soil nutrients influence spatial distributions of tropical tree species Robert John, James W. Dalling, Kyle E. Harms, Joseph B. Yavitt, Robert F. Stallard, Matthew Mirabello, Stephen P. Hubbell, Renato Valencia, Hugo Navarrete, Martha Vallejo, and Robin B. Foster Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 864–869. Published online 2007 January 10. doi: 10.1073/pnas.0604666104.PMCID: PMC1783405 Evolution INAUGURAL ARTICLE by a Recently Elected Academy Member: Two different domains of the luciferase gene in the heterotrophic dinoflagellate Noctiluca scintillans occur as two separate genes in photosynthetic species Liyun Liu and J. Woodland Hastings Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 696–701. Published online 2006 November 27. doi: 10.1073/pnas.0607816103.PMCID: PMC1783376 Improved evolutionary optimization from genetically adaptive multimethod search Jasper A. Vrugt and Bruce A. Robinson Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 708–711. Published online 2007 January 10. doi: 10.1073/pnas.0610471104.PMCID: PMC1766340 Ancestral genome sizes specify the minimum rate of lateral gene transfer during prokaryote evolution Tal Dagan and William Martin Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 870–875. Published online 2007 January 9. doi: 10.1073/pnas.0606318104.PMCID: PMC1783406 From the Cover: Cooperation and conflict in microbial biofilms Joao B. Xavier and Kevin R. Foster Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 876–881. Published online 2007 January 8. doi: 10.1073/pnas.0607651104.PMCID: PMC1783407 Modern origin of numerous alternatively spliced human introns from tandem arrays Degen Zhuo, Richard Madden, Sherif Abou Elela, and Benoit Chabot Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 882–886. Published online 2007 January 8. doi: 10.1073/pnas.0604777104.PMCID: PMC1783408 Global patterns of diversification in the history of modern amphibians Kim Roelants, David J. Gower, Mark Wilkinson, Simon P. Loader, S. D. Biju, Karen Guillaume, Linde Moriau, and Franky Bossuyt Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 887–892. Published online 2007 January 9. doi: 10.1073/pnas.0608378104.PMCID: PMC1783409 Genetics Role of SUMO in the dynamics of telomere maintenance in fission yeast Blerta Xhemalce, Eva Madi Riising, Peter Baumann, Anne Dejean, Benoît Arcangioli, and Jacob-S. Seeler Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 893–898. Published online 2007 January 5. doi: 10.1073/pnas.0605442104.PMCID: PMC1783410 Epigenetic memory at malaria virulence genes Thanat Chookajorn, Ron Dzikowski, Matthias Frank, Felomena Li, Alisha Z. Jiwani, Daniel L. Hartl, and Kirk W. Deitsch Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 899–902. Published online 2007 January 5. doi: 10.1073/pnas.0609084103.PMCID: PMC1764221 Immunology Role for rearranged variable gene segments in directing secondary T cell receptor α recombination Abbas Hawwari and Michael S. Krangel Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 903–907. Published online 2007 January 8. doi: 10.1073/pnas.0608248104.PMCID: PMC1783412 Negative feedback loop in T cell activation through IκB kinase-induced phosphorylation and degradation of Bcl10 Camille Lobry, Tatiana Lopez, Alain Israël, and Robert Weil Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 908–913. Published online 2007 January 9. doi: 10.1073/pnas.0606982104.PMCID: PMC1783413 Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFκB Hai-Chon Lee and Steven F. Ziegler Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 914–919. Published online 2007 January 9. doi: 10.1073/pnas.0607305104.PMCID: PMC1783414 Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis Francesca Odoardi, Naoto Kawakami, Zhaoxia Li, Chiara Cordiglieri, Kristina Streyl, Mikhail Nosov, Wolfgang E. F. Klinkert, Joachim W. Ellwart, Jan Bauer, Hans Lassmann, Hartmut Wekerle, and Alexander Flügel Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 920–925. Published online 2007 January 9. doi: 10.1073/pnas.0608383104.PMCID: PMC1783415 WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP) Miguel A. de la Fuente, Yoji Sasahara, Marco Calamito, Inés M. Antón, Abdallah Elkhal, Maria D. Gallego, Koduru Suresh, Katherine Siminovitch, Hans D. Ochs, Kenneth C. Anderson, Fred S. Rosen, Raif S. Geha, and Narayanaswamy Ramesh Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 926–931. Published online 2007 January 9. doi: 10.1073/pnas.0610275104.PMCID: PMC1783416 Medical Sciences Biomimetic amplification of nanoparticle homing to tumors Dmitri Simberg, Tasmia Duza, Ji Ho Park, Markus Essler, Jan Pilch, Lianglin Zhang, Austin M. Derfus, Meng Yang, Robert M. Hoffman, Sangeeta Bhatia, Michael J. Sailor, and Erkki Ruoslahti Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 932–936. Published online 2007 January 10. doi: 10.1073/pnas.0610298104.PMCID: PMC1783417 From the Cover: Small-molecule agonists for the glucagon-like peptide 1 receptor Lotte Bjerre Knudsen, Dan Kiel, Min Teng, Carsten Behrens, Dilip Bhumralkar, János T. Kodra, Jens J. Holst, Claus B. Jeppesen, Michael D. Johnson, Johannes Cornelis de Jong, Anker Steen Jorgensen, Tim Kercher, Jarek Kostrowicki, Peter Madsen, Preben H. Olesen, Jacob S. Petersen, Fritz Poulsen, Ulla G. Sidelmann, Jeppe Sturis, Larry Truesdale, John May, and Jesper Lau Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 937–942. Published online 2007 January 9. doi: 10.1073/pnas.0605701104.PMCID: PMC1783418 From the Cover: A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice Desu Chen, Jiayu Liao, Na Li, Caihong Zhou, Qing Liu, Guangxing Wang, Rui Zhang, Song Zhang, Lilin Lin, Kaixian Chen, Xin Xie, Fajun Nan, Andrew A. Young, and Ming-Wei Wang Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 943–948. Published online 2007 January 9. doi: 10.1073/pnas.0610173104.PMCID: PMC1764862 Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1 Sophie Bensing, Sergueï O. Fetissov, Jan Mulder, Jaakko Perheentupa, Jan Gustafsson, Eystein S. Husebye, Mikael Oscarson, Olov Ekwall, Patricia A. Crock, Tomas Hökfelt, Anna-Lena Hulting, and Olle Kämpe Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 949–954. Published online 2007 January 10. doi: 10.1073/pnas.0610070104.PMCID: PMC1783420 Molecular markers of early Parkinson's disease based on gene expression in blood Clemens R. Scherzer, Aron C. Eklund, Lee J. Morse, Zhixiang Liao, Joseph J. Locascio, Daniel Fefer, Michael A. Schwarzschild, Michael G. Schlossmacher, Michael A. Hauser, Jeffery M. Vance, Lewis R. Sudarsky, David G. Standaert, John H. Growdon, Roderick V. Jensen, and Steven R. Gullans Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 955–960. Published online 2007 January 10. doi: 10.1073/pnas.0610204104.PMCID: PMC1766335 Detecting and assessing macrophages in vivo to evaluate atherosclerosis noninvasively using molecular MRI Vardan Amirbekian, Michael J. Lipinski, Karen C. Briley-Saebo, Smbat Amirbekian, Juan Gilberto S. Aguinaldo, David B. Weinreb, Esad Vucic, Juan C. Frias, Fabien Hyafil, Venkatesh Mani, Edward A. Fisher, and Zahi A. Fayad Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 961–966. Published online 2007 January 10. doi: 10.1073/pnas.0606281104.PMCID: PMC1766334 Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis Michael I. Dorrell, Edith Aguilar, Lea Scheppke, Faith H. Barnett, and Martin Friedlander Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 967–972. Published online 2007 January 8. doi: 10.1073/pnas.0607542104.PMCID: PMC1764763 Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma M. E. Prince, R. Sivanandan, A. Kaczorowski, G. T. Wolf, M. J. Kaplan, P. Dalerba, I. L. Weissman, M. F. Clarke, and L. E. Ailles Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 973–978. Published online 2007 January 8. doi: 10.1073/pnas.0610117104.PMCID: PMC1783424 From the Cover: Mechanisms underlying the resistance to diet-induced obesity in germ-free mice Fredrik Bäckhed, Jill K. Manchester, Clay F. Semenkovich, and Jeffrey I. Gordon Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 979–984. Published online 2007 January 8. doi: 10.1073/pnas.0605374104.PMCID: PMC1764762 A functional SNP of interferon-γ gene is important for interferon-α-induced and spontaneous recovery from hepatitis C virus infection Ying Huang, Huiying Yang, Brian B. Borg, Xiaowen Su, Shannon L. Rhodes, Kai Yang, Xiaomei Tong, George Tang, Charles D. Howell, Hugo R. Rosen, Chloe L. Thio, David L. Thomas, Harvey J. Alter, Ronda K. Sapp, and T. Jake Liang Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 985–990. Published online 2007 January 10. doi: 10.1073/pnas.0609954104.PMCID: PMC1783426 Mitochondrial dysfunction in the pathogenesis of Ullrich congenital muscular dystrophy and prospective therapy with cyclosporins Alessia Angelin, Tania Tiepolo, Patrizia Sabatelli, Paolo Grumati, Natascha Bergamin, Cristina Golfieri, Elisabetta Mattioli, Francesca Gualandi, Alessandra Ferlini, Luciano Merlini, Nadir M. Maraldi, Paolo Bonaldo, and Paolo Bernardi Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 991–996. Published online 2007 January 10. doi: 10.1073/pnas.0610270104.PMCID: PMC1783427 Microbiology From the Cover: A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system Ivo G. Boneca, Olivier Dussurget, Didier Cabanes, Marie-Anne Nahori, Sandra Sousa, Marc Lecuit, Emmanuel Psylinakis, Vassilis Bouriotis, Jean-Pierre Hugot, Marco Giovannini, Anthony Coyle, John Bertin, Abdelkader Namane, Jean-Claude Rousselle, Nadège Cayet, Marie-Christine Prévost, Viviane Balloy, Michel Chignard, Dana J. Philpott, Pascale Cossart, and Stephen E. Girardin Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 997–1002. Published online 2007 January 10. doi: 10.1073/pnas.0609672104.PMCID: PMC1766339 Rhomboid protease AarA mediates quorum-sensing in Providencia stuartii by activating TatA of the twin-arginine translocase Lindsay G. Stevenson, Kvido Strisovsky, Katy M. Clemmer, Shantanu Bhatt, Matthew Freeman, and Philip N. Rather Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1003–1008. Published online 2007 January 10. doi: 10.1073/pnas.0608140104.PMCID: PMC1783354 A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate Larry A. Gallagher, Elizabeth Ramage, Michael A. Jacobs, Rajinder Kaul, Mitchell Brittnacher, and Colin Manoil Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1009–1014. Published online 2007 January 10. doi: 10.1073/pnas.0606713104.PMCID: PMC1783355 HIV-susceptible transgenic rats allow rapid preclinical testing of antiviral compounds targeting virus entry or reverse transcription Christine Goffinet, Ina Allespach, and Oliver T. Keppler Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1015–1020. Published online 2007 January 5. doi: 10.1073/pnas.0607414104.PMCID: PMC1783356 A natural genetic code expansion cassette enables transmissible biosynthesis and genetic encoding of pyrrolysine David G. Longstaff, Ross C. Larue, Joseph E. Faust, Anirban Mahapatra, Liwen Zhang, Kari B. Green-Church, and Joseph A. Krzycki Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1021–1026. Published online 2007 January 4. doi: 10.1073/pnas.0610294104.PMCID: PMC1783357 Neuroscience Controlled expression of transgenes introduced by in vivo electroporation Takahiko Matsuda and Constance L. Cepko Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1027–1032. Published online 2007 January 5. doi: 10.1073/pnas.0610155104.PMCID: PMC1764220 Differential distribution of NCX1 contributes to spine–dendrite compartmentalization in CA1 pyramidal cells Andrea Lőrincz, Balázs Rózsa, Gergely Katona, E. Sylvester Vizi, and Gábor Tamás Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1033–1038. Published online 2007 January 10. doi: 10.1073/pnas.0605412104.PMCID: PMC1783359 A G protein/cAMP signal cascade is required for axonal convergence into olfactory glomeruli Alexander T. Chesler, Dong-Jing Zou, Claire E. Le Pichon, Zita A. Peterlin, Glennis A. Matthews, Xin Pei, Michael C. Miller, and Stuart Firestein Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1039–1044. Published online 2007 January 10. doi: 10.1073/pnas.0609215104.PMCID: PMC1783360 Further evidence that Whorfian effects are stronger in the right visual field than the left G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1097–1102. Published online 2007 January 9. doi: 10.1073/pnas.0610132104.PMCID: PMC1783370 Pharmacology In the regulation of cytochrome P450 genes, phenobarbital targets LKB1 for necessary activation of AMP-activated protein kinase Sharon M. Blättler, Franck Rencurel, Michel R. Kaufmann, and Urs A. Meyer Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1045–1050. Published online 2007 January 9. doi: 10.1073/pnas.0610216104.PMCID: PMC1783361 Physiology A quantitative, theoretical framework for understanding mammalian sleep Van M. Savage and Geoffrey B. West Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1051–1056. Published online 2007 January 10. doi: 10.1073/pnas.0610080104.PMCID: PMC1783362 Mild mitochondrial uncoupling impacts cellular aging in human muscles in vivo Catherine E. Amara, Eric G. Shankland, Sharon A. Jubrias, David J. Marcinek, Martin J. Kushmerick, and Kevin E. Conley Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1057–1062. Published online 2007 January 10. doi: 10.1073/pnas.0610131104.PMCID: PMC1766336 A blasticidin S-resistant Plasmodium falciparum mutant with a defective plasmodial surface anion channel David A. Hill, Ajay D. Pillai, Fatima Nawaz, Karen Hayton, Lanxuan Doan, Godfrey Lisk, and Sanjay A. Desai Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1063–1068. Published online 2007 January 9. doi: 10.1073/pnas.0610353104.PMCID: PMC1783364 Plant Biology Requirement of the C3HC4 zinc RING finger of the Arabidopsis PEX10 for photorespiration and leaf peroxisome contact with chloroplasts Uwe Schumann, Jakob Prestele, Henriette O'Geen, Robert Brueggeman, Gerhard Wanner, and Christine Gietl Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1069–1074. Published online 2007 January 10. doi: 10.1073/pnas.0610402104.PMCID: PMC1783365 Arabidopsis systemic immunity uses conserved defense signaling pathways and is mediated by jasmonates William Truman, Mark H. Bennett, Ines Kubigsteltig, Colin Turnbull, and Murray Grant Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1075–1080. Published online 2007 January 10. doi: 10.1073/pnas.0605423104.PMCID: PMC1783366 Conservation of B class gene expression in the second whorl of a basal grass and outgroups links the origin of lodicules and petals Clinton J. Whipple, Michael J. Zanis, Elizabeth A. Kellogg, and Robert J. Schmidt Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1081–1086. Published online 2007 January 8. doi: 10.1073/pnas.0606434104.PMCID: PMC1783367 Social Sciences Anthropology Plants and people from the Early Neolithic to Shang periods in North China Gyoung-Ah Lee, Gary W. Crawford, Li Liu, and Xingcan Chen Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1087–1092. Published online 2007 January 9. doi: 10.1073/pnas.0609763104.PMCID: PMC1764861 Economic Sciences A compensation election for binary social choice Ryan D. Oprea, Vernon L. Smith, and Abel M. Winn Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1093–1096. Published online 2007 January 10. doi: 10.1073/pnas.0609866104.PMCID: PMC1783369 Psychology Further evidence that Whorfian effects are stronger in the right visual field than the left G. V. Drivonikou, P. Kay, T. Regier, R. B. Ivry, A. L. Gilbert, A. Franklin, and I. R. L. Davies Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1097–1102. Published online 2007 January 9. doi: 10.1073/pnas.0610132104.PMCID: PMC1783370 Correction Correction for Shoshani et al., A proboscidean from the late Oligocene of Eritrea, a ‘missing link’ between early Elephantiformes and Elephantimorpha, and biogeographic implications Proc Natl Acad Sci U S A. 2007 January 16; 104(3): 1103. Published online 2006 December 28. doi: 10.1073/pnas.0610824104.PMCID: PMC1783371 Corrects: Jeheskel Shoshani, et al. A proboscidean from the late Oligocene of Eritrea, a “missing link” between early Elephantiformes and Elephantimorpha, and biogeographic implications. Proc Natl Acad Sci U S A. 2006 November 14; 103(46): 17296–17301. |