Selected Publications

Molecular Endocrinology Group

1. Gross KL, Lu NZ, Cidlowski JA. Molecular mechanisms regulating glucocorticoid sensitivity and resistance. Mol Cell Endocrinol, 2008. [Epub ahead of print]. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/19000736?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
2. Franco R, Dehaven WI, Sifre MI, Bortner CD, Cidlowski JA. Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis. J Biol Chem 283(52):36071-36087, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18940791?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
3. Galliher-Beckley AJ, Williams JG, Collins JB, Cidlowski JA. Glycogen synthase kinase 3beta-mediated serine phosphorylation of the human glucocorticoid receptor redirects gene expression profiles. Molecular and cellular biology 28(24):7309-7322, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18838540)
4. Gross KL, Cidlowski JA. Tissue-specific glucocorticoid action: A family affair. Trends in endocrinology and metabolism: TEM 19(9):331-339, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18805703)
5. Bortner CD, Sifre MI, Cidlowski JA. Cationic gradient reversal and cytoskeleton-independent volume fegulatory pathways define an early stage of apoptosis. The Journal of Biological Chemistry 283(11):7219-7229, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18187415)
6. Lu NZ, Collins JB, Grissom SF, Cidlowski JA. Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor. Molecular and Cellular Biology 27(20):7143-7160, 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17682054)
7. Franco R, Panayiotidis MI, Cidlowski JA. Glutathione depletion is necessary for apoptosis in lymphoid cells independent of reactive oxygen species formation. Journal of Biological Chemistry 282(42):30452-30465, 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17724027&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
8. Lewis-Tuffin LJ, Jewell CM, Bienstock RJ, Collins JB and Cidlowski JA.  Human glucocorticoid receptor β binds RU-486 and is transcriptionally active.  Molecular and Cellular Biology p. 2266-2282, Mar 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17242213&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
9. Lu NZ and Cidlowski JA.  Glucocorticoid receptor isoforms generate transcription specificity.  Trends in Cell Biology 16(6):301-307, 2006. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16697199&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
10. Franco R, Bortner CD and Cidlowski JA.  Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis. J. of  Membrane Biology 209: 43-58, 2006. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16685600&ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
11. Franco R and Cidlowski JA.  SLCO/OATP-like transport of glutathione in FasL-induced apoptosis.  Journal of Biological Chemistry 281 (40):29542-29557, 2006. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16857677&ordinalpos=25&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
12. Smoak K and Cidlowski JA.  Glucocorticoids regulate tristetetraprolin synthesis and posttrancriptionally regulate tumor necrosis factor alpha inflammatory signaling.  Molecular and Celullar Biology 26(23):9126-9135, 2006. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16982682&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
13. G. Heimlich and Cidlowski JA.  Selective role of intracellular chloride in the regulation of the intrinsic but not extrinsic pathway of apoptosis in Jurkat T-cells. J. Biol. Chem. 281: 2232-2241, 2006. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16299378&ordinalpos=14&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
14. Schaaf MJM, Lewis-Tuffin LJ and Cidlowski JA. Ligand-Selective Targeting of the Glucocorticoid Receptor to Nuclear Subdomains is associated with Decreased Receptor Mobility. Molecular Endocrinology 19(6): 1501-1515, 2005. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15705660&ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
15. Lu NZ and Cidlowski JA. Translational Regulatory Mechanisms Generate N-terminal Glucocorticoid Receptor Isoforms with Unique Transcriptional Target Genes. Molecular Cell. Vol.18, 331-342 April 29, 2005. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15866175&ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)
16. Hermoso MA, Matsuguchi T, Smoak K and Cidlowski JA. Glucocorticoids and Tumor Necrosis Factor Alpha Cooperatively Regulate Toll-Like Receptor 2 Gene Expression. Molecular and Cellular Biology, p.4743-4756, June 2004. [Abstract] (http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=15143169&ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum)