| | Other Issues: previous | next | latest | archiveMethodology Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease Caroline L Benn, Helen Fox, and Gillian P Bates PMCID: PMC2584034 In vivo silencing of alpha-synuclein using naked siRNA Jada Lewis, Heather Melrose, David Bumcrot, Andrew Hope, Cynthia Zehr, Sarah Lincoln, Adam Braithwaite, Zhen He, Sina Ogholikhan, Kelly Hinkle, Caroline Kent, Ivanka Toudjarska, Klaus Charisse, Ravi Braich, Rajendra K Pandey, Michael Heckman, Demetrius M Maraganore, Julia Crook, and Matthew J Farrer PMCID: PMC2612658 Research Articles Ginkgolides protect against amyloid-β1–42-mediated synapse damage in vitro Clive Bate, Mourad Tayebi, and Alun Williams PMCID: PMC2254622 Presenilins are required for maintenance of neural stem cells in the developing brain Woo-Young Kim and Jie Shen PMCID: PMC2235867 A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation Qing Yan Liu, Joy X Lei, Marianna Sikorska, and Rugao Liu PMCID: PMC2279130 Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein Celina V Zerbinatti, Joanna M Cordy, Ci-Di Chen, Maria Guillily, Sokreine Suon, William J Ray, Guy R Seabrook, Carmela R Abraham, and Benjamin Wolozin PMCID: PMC2323375 Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1 Donald B Carter, Edwige Dunn, Adele M Pauley, Denise D McKinley, Timothy J Fleck, Brenda R Ellerbrook, Nancy C Stratman, Xiangdong Zhou, Carol S Himes, Jeffrey S Nye, Alfredo Tomasselli, and Riqiang Yan PMCID: PMC2405781 Autoimmune-induced preferential depletion of myelin-associated glycoprotein (MAG) is genetically regulated in relapsing EAE (B6 × SJL) F1 mice Dusanka S Skundric, Rujuan Dai, Vaagn L Zakarian, and Weili Zhou PMCID: PMC2459167 Prion protein lacks robust cytoprotective activity in cultured cells Heather M Christensen and David A Harris PMCID: PMC2546390 Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role Luca Giliberto, Dawang Zhou, Richard Weldon, Elena Tamagno, Pasquale De Luca, Massimo Tabaton, and Luciano D'Adamio PMCID: PMC2538519 Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice Károly Mirnics, Eric M Norstrom, Krassimira Garbett, Se Hoon Choi, Xiaoqiong Zhang, Philip Ebert, and Sangram S Sisodia PMCID: PMC2569036 Evaluation of Dimebon in cellular model of Huntington's disease Jun Wu, Qin Li, and Ilya Bezprozvanny PMCID: PMC2577671 Formation of soluble amyloid oligomers and amyloid fibrils by the multifunctional protein vitronectin Thuzar M Shin, J Mario Isas, Chia-Ling Hsieh, Rakez Kayed, Charles G Glabe, Ralf Langen, and Jeannie Chen PMCID: PMC2577670 NG2 cells response to axonal alteration in the spinal cord white matter in mice with genetic disruption of neurofilament light subunit expression Ya Jun Wu, Ya Fang Tang, Zhi Cheng Xiao, Zhen Min Bao, and Bei Ping He PMCID: PMC2584033 Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations Chera L Maarouf, Ian D Daugs, Salvatore Spina, Ruben Vidal, Tyler A Kokjohn, R Lyle Patton, Walter M Kalback, Dean C Luehrs, Douglas G Walker, Eduardo M Castaño, Thomas G Beach, Bernardino Ghetti, and Alex E Roher PMCID: PMC2600784 Reviews Tau exon 10 alternative splicing and tauopathies Fei Liu and Cheng-Xin Gong PMCID: PMC2483273 The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease Nibaldo C Inestrosa and Enrique M Toledo PMCID: PMC2515306 Short Reports Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons Danling Wang, Beisha Tang, Guohua Zhao, Qian Pan, Kun Xia, Rolf Bodmer, and Zhuohua Zhang PMCID: PMC2276501 MicroRNAs can regulate human APP levels Neha Patel, David Hoang, Nathan Miller, Sara Ansaloni, Qihong Huang, Jack T Rogers, Jeremy C Lee, and Aleister J Saunders PMCID: PMC2529281 Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease Kathryn J Bryan, Xiongwei Zhu, Peggy L Harris, George Perry, Rudy J Castellani, Mark A Smith, and Gemma Casadesus PMCID: PMC2565661 |
