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Technologies/Expertise
Amino Acid Microsequencing
Preparation of protein samples for amino acid analysis
Protein microsequencing (Edman degradation)
Biocore® Analysis of Macromolecular Interactions
Data analysis
Macromolecular interactions: DNA-protein, protein-protein, protein-ligand interactions
Molecular mechanism-based small molecule inhibitor screen
Fluorescence Anisotropy
High through-put molecular screens
MALDI-TOF Mass Spectrometry
MALDI-TOF mass spectrometry studies of proteins, peptides, DNA, and carbohydrates
Protein Identification
Bioinformatic analysis of sequence data
Chromatographic protein separation (ion-exchange, gel-filtration, reverse-phase chromatography, HPLC)
One- and two-dimensional gel electrophoresis with preservation of biological activity
Protein identification by Peptide Mass Fingerprinting (PMF) using enzymatic digestion and MALDI-TOF mass spectrometry
Proteolytic chemical fragmentation and purification of resultant peptides and proteins
Western blot analysis
