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Volume 7;  2008
Commentary
Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment
Christopher A Maxwell, Víctor Moreno, Xavier Solé, Laia Gómez, Pilar Hernández, Ander Urruticoechea, and Miguel Angel Pujana
Mol Cancer. 2008; 7: 4. Published online 2008 January 10. doi: 10.1186/1476-4598-7-4.
PMCID: PMC2244643
Reviews
The LIM and SH3 domain protein family: structural proteins or signal transducers or both?
Thomas GP Grunewald and Elke Butt
Mol Cancer. 2008; 7: 31. Published online 2008 April 17. doi: 10.1186/1476-4598-7-31.
PMCID: PMC2359764
Evaluation of cell types for assessment of cytogenetic damage in arsenic exposed population
Pritha Ghosh, Arindam Basu, Keshav K Singh, and Ashok K Giri
Mol Cancer. 2008; 7: 45. Published online 2008 May 28. doi: 10.1186/1476-4598-7-45.
PMCID: PMC2430711
Apoptotic pathways in pancreatic ductal adenocarcinoma
Rainer Hamacher, Roland M Schmid, Dieter Saur, and Günter Schneider
Mol Cancer. 2008; 7: 64. Published online 2008 July 24. doi: 10.1186/1476-4598-7-64.
PMCID: PMC2515336
DNA methylation-based biomarkers for early detection of non-small cell lung cancer: an update
Paul P Anglim, Todd A Alonzo, and Ite A Laird-Offringa
Mol Cancer. 2008; 7: 81. Published online 2008 October 23. doi: 10.1186/1476-4598-7-81.
PMCID: PMC2585582
The prince and the pauper. A tale of anticancer targeted agents
Alfonso Dueñas-González, Patricia García-López, Luis Alonso Herrera, Jose Luis Medina-Franco, Aurora González-Fierro, and Myrna Candelaria
Mol Cancer. 2008; 7: 82. Published online 2008 October 23. doi: 10.1186/1476-4598-7-82.
PMCID: PMC2615789
Tissue Inhibitor of Metalloproteinases-4. The road less traveled
Jorge Melendez-Zajgla, Luis Del Pozo, Gisela Ceballos, and Vilma Maldonado
Mol Cancer. 2008; 7: 85. Published online 2008 November 21. doi: 10.1186/1476-4598-7-85.
PMCID: PMC2599898
Short Communications
Intravenous administration of the conditionally replicative adenovirus Ad5-Δ24RGD induces regression of osteosarcoma lung metastases
Harm CA Graat, Victor W van Beusechem, Frederik HE Schagen, M Adhiambo Witlox, Eugenie S Kleinerman, Marco N Helder, Winald R Gerritsen, Gertjan JL Kaspers, and Paul IJM Wuisman
Mol Cancer. 2008; 7: 9. Published online 2008 January 23. doi: 10.1186/1476-4598-7-9.
PMCID: PMC2254437
A quantitative PCR method to detect blood microRNAs associated with tumorigenesis in transgenic mice
Alice C Fan, Marianna M Goldrick, Jennifer Ho, Yu Liang, Pavan Bachireddy, and Dean W Felsher
Mol Cancer. 2008; 7: 74. Published online 2008 September 30. doi: 10.1186/1476-4598-7-74.
PMCID: PMC2572631
Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?
Puri Catalina, Rosa Montes, Gertru Ligero, Laura Sanchez, Teresa de la Cueva, Clara Bueno, Paola E Leone, and Pablo Menendez
Mol Cancer. 2008; 7: 76. Published online 2008 October 3. doi: 10.1186/1476-4598-7-76.
PMCID: PMC2567976
Bone marrow ectopic expression of a non-coding RNA in childhood T-cell acute lymphoblastic leukemia with a novel t(2;11)(q11.2;p15.1) translocation
Maria Corsignano Guastadisegni, Angelo Lonoce, Luciana Impera, Francesco Albano, Pietro D'Addabbo, Sebastiano Caruso, Isabella Vasta, Ioannis Panagopoulos, Anna Leszl, Giuseppe Basso, Mariano Rocchi, and Clelia Tiziana Storlazzi
Mol Cancer. 2008; 7: 80. Published online 2008 October 23. doi: 10.1186/1476-4598-7-80.
PMCID: PMC2579299
Editorials
To know or not to know: archiving and the under-appreciated historical value of data
David Covarrubias, Maurice Van Emburgh, Hassan R Naqvi, Christian Schmidt, and Shawn Mathur
Mol Cancer. 2008; 7: 18. Published online 2008 February 11. doi: 10.1186/1476-4598-7-18.
PMCID: PMC2257976
Another challenge for scientists
Laura M Christian, Hassan R Naqvi, Christian Schmidt, David Covarrubias, and Shawn Mathur
Mol Cancer. 2008; 7: 63. Published online 2008 July 17. doi: 10.1186/1476-4598-7-63.
PMCID: PMC2517074
The problem of choice
Hassan R Naqvi, Shawn Mathur, David Covarrubias, Josephine A Curcio, and Christian Schmidt
Mol Cancer. 2008; 7: 86. Published online 2008 November 23. doi: 10.1186/1476-4598-7-86.
PMCID: PMC2599897
Research
Identification and transcript analysis of a novel wallaby (Macropus eugenii) basal-like breast cancer cell line
Julie A Sharp, Sonia L Mailer, Peter C Thomson, Christophe Lefèvre, and Kevin R Nicholas
Mol Cancer. 2008; 7: 1. Published online 2008 January 7. doi: 10.1186/1476-4598-7-1.
PMCID: PMC2263075
Sub-megabase resolution tiling (SMRT) array-based comparative genomic hybridization profiling reveals novel gains and losses of chromosomal regions in Hodgkin Lymphoma and Anaplastic Large Cell Lymphoma cell lines
Faisal M Fadlelmola, Minglong Zhou, Ronald J de Leeuw, Nirpjit S Dosanjh, Karynn Harmer, David Huntsman, Wan L Lam, and Diponkar Banerjee
Mol Cancer. 2008; 7: 2. Published online 2008 January 7. doi: 10.1186/1476-4598-7-2.
PMCID: PMC2254646
Down-regulation of transforming growth factor-β type II receptor (TGF-βRII) protein and mRNA expression in cervical cancer
Jose Diaz-Chavez, Rogelio Hernandez-Pando, Paul F Lambert, and Patricio Gariglio
Mol Cancer. 2008; 7: 3. Published online 2008 January 9. doi: 10.1186/1476-4598-7-3.
PMCID: PMC2248208
The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer
Fan Cheng, Patricia J McLaughlin, Michael F Verderame, and Ian S Zagon
Mol Cancer. 2008; 7: 5. Published online 2008 January 11. doi: 10.1186/1476-4598-7-5.
PMCID: PMC2253554
Genome-wide screening of copy number alterations and LOH events in renal cell carcinomas and integration with gene expression profile
Ingrid Cifola, Roberta Spinelli, Luca Beltrame, Clelia Peano, Ester Fasoli, Stefano Ferrero, Silvano Bosari, Stefano Signorini, Francesco Rocco, Roberto Perego, Vanessa Proserpio, Francesca Raimondo, Paolo Mocarelli, and Cristina Battaglia
Mol Cancer. 2008; 7: 6. Published online 2008 January 14. doi: 10.1186/1476-4598-7-6.
PMCID: PMC2253555
Differential expression of metallothioneins (MTs) 1, 2, and 3 in response to zinc treatment in human prostate normal and malignant cells and tissues
Hua Wei, Mohamed Mokhtar Desouki, Shufei Lin, Dakai Xiao, Renty B Franklin, and Pei Feng
Mol Cancer. 2008; 7: 7. Published online 2008 January 21. doi: 10.1186/1476-4598-7-7.
PMCID: PMC2265743
An integrative model for recurrence in ovarian cancer
Alexandros Laios, Sharon A O'Toole, Richard Flavin, Cara Martin, Martina Ring, Noreen Gleeson, Tom D'Arcy, Eamonn PJ McGuinness, Orla Sheils, Brian L Sheppard, and John J O' Leary
Mol Cancer. 2008; 7: 8. Published online 2008 January 22. doi: 10.1186/1476-4598-7-8.
PMCID: PMC2248209
Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors
Samy L Habib, Simona Simone, Jeff J Barnes, and Hanna E Abboud
Mol Cancer. 2008; 7: 10. Published online 2008 January 24. doi: 10.1186/1476-4598-7-10.
PMCID: PMC2265742
Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice
Archana Thakur, Aliccia Bollig, Jiusheng Wu, and Dezhong J Liao
Mol Cancer. 2008; 7: 11. Published online 2008 January 24. doi: 10.1186/1476-4598-7-11.
PMCID: PMC2259361
Constitutive overexpression of a novel 21 kDa protein by Hodgkin Lymphoma and Aggressive Non-Hodgkin Lymphomas
Minglong Zhou, Faisal M Fadlelmola, Jason B Cohn, Brian Skinnider, Randy D Gascoyne, and Diponkar Banerjee
Mol Cancer. 2008; 7: 12. Published online 2008 January 24. doi: 10.1186/1476-4598-7-12.
PMCID: PMC2267462
Insulin-like growth factor-I gene therapy reverses morphologic changes and reduces hyperprolactinemia in experimental rat prolactinomas
Gloria M Console, Claudia B Herenu, Gisela A Camihort, Georgina C Luna, Maria I Bracamonte, Gustavo R Morel, and Rodolfo G Goya
Mol Cancer. 2008; 7: 13. Published online 2008 January 25. doi: 10.1186/1476-4598-7-13.
PMCID: PMC2263076
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Nadia Vié, Virginie Copois, Caroline Bascoul-Mollevi, Vincent Denis, Nicole Bec, Bruno Robert, Caroline Fraslon, Emmanuel Conseiller, Franck Molina, Christian Larroque, Pierre Martineau, Maguy Del Rio, and Céline Gongora
Mol Cancer. 2008; 7: 14. Published online 2008 January 25. doi: 10.1186/1476-4598-7-14.
PMCID: PMC2245978
DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
J Devon Roll, Ashley G Rivenbark, Wendell D Jones, and William B Coleman
Mol Cancer. 2008; 7: 15. Published online 2008 January 25. doi: 10.1186/1476-4598-7-15.
PMCID: PMC2246151
Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
Sharmila Shankar, Suthakar Ganapathy, Qinghe Chen, and Rakesh K Srivastava
Mol Cancer. 2008; 7: 16. Published online 2008 January 29. doi: 10.1186/1476-4598-7-16.
PMCID: PMC2249593
Inducing apoptosis of human colon cancer cells by an IGF-I D domain analogue peptide
Shi Yu Yang, Kevin M Sales, Barry J Fuller, Alexander M Seifalian, and Marc C Winslet
Mol Cancer. 2008; 7: 17. Published online 2008 February 8. doi: 10.1186/1476-4598-7-17.
PMCID: PMC2276513
Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo
Xinrui Yan, Mei-Sze Chua, Jing He, and Samuel K So
Mol Cancer. 2008; 7: 19. Published online 2008 February 12. doi: 10.1186/1476-4598-7-19.
PMCID: PMC2276234
Preclinical studies of Apogossypolone: a new nonpeptidic pan small-molecule inhibitor of Bcl-2, Bcl-XL and Mcl-1 proteins in Follicular Small Cleaved Cell Lymphoma model
Alan A Arnold, Amro Aboukameel, Jianyong Chen, Dajun Yang, Shaomeng Wang, Ayad Al-Katib, and Ramzi M Mohammad
Mol Cancer. 2008; 7: 20. Published online 2008 February 14. doi: 10.1186/1476-4598-7-20.
PMCID: PMC2265299
Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma
Madeleine Austinat, Ruediger Dunsch, Christian Wittekind, Andrea Tannapfel, Rolf Gebhardt, and Frank Gaunitz
Mol Cancer. 2008; 7: 21. Published online 2008 February 18. doi: 10.1186/1476-4598-7-21.
PMCID: PMC2287186
In Silico analysis of Gastric carcinoma Serial Analysis of Gene Expression libraries reveals different profiles associated with ethnicity
Francisco J Ossandon, Cynthia Villarroel, Francisco Aguayo, Eudocia Santibanez, Naohide Oue, Wataru Yasui, and Alejandro H Corvalan
Mol Cancer. 2008; 7: 22. Published online 2008 February 27. doi: 10.1186/1476-4598-7-22.
PMCID: PMC2323622
Lymphangiogenesis and lymph node metastasis in breast cancer
Giles H Cunnick, Wen G Jiang, Tony Douglas-Jones, Gareth Watkins, Kelvin F Gomez, Mike J Morgan, Ashok Subramanian, Kefah Mokbel, and Robert E Mansel
Mol Cancer. 2008; 7: 23. Published online 2008 March 6. doi: 10.1186/1476-4598-7-23.
PMCID: PMC2278160
Phenylbutyrate interferes with the Fanconi anemia and BRCA pathway and sensitizes head and neck cancer cells to cisplatin
Kyunghee Burkitt and Mats Ljungman
Mol Cancer. 2008; 7: 24. Published online 2008 March 6. doi: 10.1186/1476-4598-7-24.
PMCID: PMC2276233
The Involvement of Bax in Zinc-Induced Mitochondrial Apoptogenesis in Malignant Prostate Cells
Pei Feng, Tieluo Li, Zhixin Guan, Renty B Franklin, and Leslie C Costello
Mol Cancer. 2008; 7: 25. Published online 2008 March 10. doi: 10.1186/1476-4598-7-25.
PMCID: PMC2329666
Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells
Anna Jankowska, Samuel I Gunderson, Miroslaw Andrusiewicz, Beata Burczynska, Anna Szczerba, Artur Jarmolowski, Ewa Nowak-Markwitz, and Jerzy B Warchol
Mol Cancer. 2008; 7: 26. Published online 2008 March 14. doi: 10.1186/1476-4598-7-26.
PMCID: PMC2335103
Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity
Audrey Sermeus, Jean-Philippe Cosse, Marianne Crespin, Veronique Mainfroid, Francoise de Longueville, Noelle Ninane, Martine Raes, Jose Remacle, and Carine Michiels
Mol Cancer. 2008; 7: 27. Published online 2008 March 26. doi: 10.1186/1476-4598-7-27.
PMCID: PMC2330149
Transduction of E2F-1 TAT fusion proteins represses expression of hTERT in primary ductal breast carcinoma cell lines
Kimberly A Elliott, Lee F Rickords, and J Marcelete Labrum
Mol Cancer. 2008; 7: 28. Published online 2008 March 26. doi: 10.1186/1476-4598-7-28.
PMCID: PMC2346477
Molecular analysis reveals heterogeneity of mouse mammary tumors conditionally mutant for Brca1
Mollie H Wright, Ana I Robles, Jason I Herschkowitz, Melinda G Hollingshead, Miriam R Anver, Charles M Perou, and Lyuba Varticovski
Mol Cancer. 2008; 7: 29. Published online 2008 April 7. doi: 10.1186/1476-4598-7-29.
PMCID: PMC2329667
Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cγ at the centrosome
Hélène Lelièvre, Véronique Chevrier, Anne-Marie Tassin, and Daniel Birnbaum
Mol Cancer. 2008; 7: 30. Published online 2008 April 15. doi: 10.1186/1476-4598-7-30.
PMCID: PMC2373309
DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein
Jing An, Dong-Yan Yang, Qin-Zhi Xu, Shi-Meng Zhang, Yan-Ying Huo, Zeng-Fu Shang, Yu Wang, De-Chang Wu, and Ping-Kun Zhou
Mol Cancer. 2008; 7: 32. Published online 2008 April 22. doi: 10.1186/1476-4598-7-32.
PMCID: PMC2383926
Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning 1H magnetic resonance spectroscopy
Therese Seierstad, Kathrine Røe, Beathe Sitter, Jostein Halgunset, Kjersti Flatmark, Anne H Ree, Dag Rune Olsen, Ingrid S Gribbestad, and Tone F Bathen
Mol Cancer. 2008; 7: 33. Published online 2008 April 25. doi: 10.1186/1476-4598-7-33.
PMCID: PMC2377266
Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation
Giorgia Egidy, Sophia Julé, Philippe Bossé, Florence Bernex, Claudine Geffrotin, Silvia Vincent-Naulleau, Vratislav Horak, Xavier Sastre-Garau, and Jean-Jacques Panthier
Mol Cancer. 2008; 7: 34. Published online 2008 April 28. doi: 10.1186/1476-4598-7-34.
PMCID: PMC2387171
Potential role of miR-9 and miR-223 in recurrent ovarian cancer
Alexandros Laios, Sharon O'Toole, Richard Flavin, Cara Martin, Lynn Kelly, Martina Ring, Stephen P Finn, Ciara Barrett, Massimo Loda, Noreen Gleeson, Tom D'Arcy, Eamonn McGuinness, Orla Sheils, Brian Sheppard, and John O' Leary
Mol Cancer. 2008; 7: 35. Published online 2008 April 28. doi: 10.1186/1476-4598-7-35.
PMCID: PMC2383925
DNA repair gene ERCC2 polymorphisms and associations with breast and ovarian cancer risk
Dominique Bernard-Gallon, Rémy Bosviel, Laetitia Delort, Luc Fontana, Alain Chamoux, Nadège Rabiau, Fabrice Kwiatkowski, Nasséra Chalabi, Samir Satih, and Yves-Jean Bignon
Mol Cancer. 2008; 7: 36. Published online 2008 May 2. doi: 10.1186/1476-4598-7-36.
PMCID: PMC2394522
Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
Purna Mukherjee, Tiernan J Mulrooney, Jeremy Marsh, Derek Blair, Thomas C Chiles, and Thomas N Seyfried
Mol Cancer. 2008; 7: 37. Published online 2008 May 12. doi: 10.1186/1476-4598-7-37.
PMCID: PMC2397440
COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro
Huan-Ching Chuang, Adel Kardosh, Kevin J Gaffney, Nicos A Petasis, and Axel H Schönthal
Mol Cancer. 2008; 7: 38. Published online 2008 May 16. doi: 10.1186/1476-4598-7-38.
PMCID: PMC2396175
Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas
Kenneth A Field, Soratree Charoenthongtrakul, J Michael Bishop, and Yosef Refaeli
Mol Cancer. 2008; 7: 39. Published online 2008 May 19. doi: 10.1186/1476-4598-7-39.
PMCID: PMC2409375
Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
David T Yang, Ken H Young, Brad S Kahl, Stephanie Markovina, and Shigeki Miyamoto
Mol Cancer. 2008; 7: 40. Published online 2008 May 19. doi: 10.1186/1476-4598-7-40.
PMCID: PMC2408930
Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile
François Ducray, Ahmed Idbaih, Aurélien de Reyniès, Ivan Bièche, Joëlle Thillet, Karima Mokhtari, Séverine Lair, Yannick Marie, Sophie Paris, Michel Vidaud, Khê Hoang-Xuan, Olivier Delattre, Jean-Yves Delattre, and Marc Sanson
Mol Cancer. 2008; 7: 41. Published online 2008 May 20. doi: 10.1186/1476-4598-7-41.
PMCID: PMC2415112
Evidence for efficient phosphorylation of EGFR and rapid endocytosis of phosphorylated EGFR via the early/late endocytic pathway in a gefitinib-sensitive non-small cell lung cancer cell line
Yukio Nishimura, Kiyoko Yoshioka, Biborka Bereczky, and Kazuyuki Itoh
Mol Cancer. 2008; 7: 42. Published online 2008 May 21. doi: 10.1186/1476-4598-7-42.
PMCID: PMC2412912
Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors
Laura Menendez, L DeEtte Walker, Lilya V Matyunina, Kimberly A Totten, Benedict B Benigno, and John F McDonald
Mol Cancer. 2008; 7: 43. Published online 2008 May 22. doi: 10.1186/1476-4598-7-43.
PMCID: PMC2429914
ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells
Karen Denning, Paul Smyth, Susanne Cahill, Jinghuan Li, Richard Flavin, Sinead Aherne, John J O' Leary, and Orla Sheils
Mol Cancer. 2008; 7: 44. Published online 2008 May 27. doi: 10.1186/1476-4598-7-44.
PMCID: PMC2423371
Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms
Shikha Gaur, John E Shively, Yun Yen, and Rajesh K Gaur
Mol Cancer. 2008; 7: 46. Published online 2008 May 28. doi: 10.1186/1476-4598-7-46.
PMCID: PMC2490704
Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of Head and Neck cancers
Samah Abu-Ali, Abbas Fotovati, and Kanemitsu Shirasuna
Mol Cancer. 2008; 7: 47. Published online 2008 June 3. doi: 10.1186/1476-4598-7-47.
PMCID: PMC2464604
DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH
Stine H Kresse, Magne Skårn, Hege O Ohnstad, Heidi M Namløs, Bodil Bjerkehagen, Ola Myklebost, and Leonardo A Meza-Zepeda
Mol Cancer. 2008; 7: 48. Published online 2008 June 3. doi: 10.1186/1476-4598-7-48.
PMCID: PMC2442610
Meta-analysis of human cancer microarrays reveals GATA3 is integral to the estrogen receptor alpha pathway
Brian J Wilson and Vincent Giguère
Mol Cancer. 2008; 7: 49. Published online 2008 June 4. doi: 10.1186/1476-4598-7-49.
PMCID: PMC2430971
Effect of bortezomib on human neuroblastoma: analysis of molecular mechanisms involved in cytotoxicity
Valérie Combaret, Sandrine Boyault, Isabelle Iacono, Stéphanie Brejon, Raphaël Rousseau, and Alain Puisieux
Mol Cancer. 2008; 7: 50. Published online 2008 June 5. doi: 10.1186/1476-4598-7-50.
PMCID: PMC2442611
Transformation of MCF-10A cells by random mutagenesis with frameshift mutagen ICR191: A model for identifying candidate breast-tumor suppressors
Helena Zientek-Targosz, Dimiter Kunnev, Lesleyann Hawthorn, Mikhail Venkov, Sei-Ichi Matsui, Richard T Cheney, and Yuri Ionov
Mol Cancer. 2008; 7: 51. Published online 2008 June 5. doi: 10.1186/1476-4598-7-51.
PMCID: PMC2430587
Involvement of GTA protein NC2β in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation
Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Veronica Giunta, Antonella Rapisarda, Elisa Tricarichi, Marco Miceli, Rosario Angelica, Agata Grillo, Barbara Banelli, Isabella Defferari, Stefano Forte, Alessandro Laganà, Camillo Bosco, Rosalba Giugno, Alfredo Pulvirenti, Alfredo Ferro, Karl H Grzeschik, Andrea Di Cataldo, Gian P Tonini, Massimo Romani, and Michele Purrello
Mol Cancer. 2008; 7: 52. Published online 2008 June 6. doi: 10.1186/1476-4598-7-52.
PMCID: PMC2443168
Stabilizing mutation of CTNNB1/beta-catenin and protein accumulation analyzed in a large series of parathyroid tumors of Swedish patients
Peyman Björklund, Daniel Lindberg, Göran Åkerström, and Gunnar Westin
Mol Cancer. 2008; 7: 53. Published online 2008 June 9. doi: 10.1186/1476-4598-7-53.
PMCID: PMC2435117
Resistance of mitochondrial p53 to dominant inhibition
Kristina Heyne, Katrin Schmitt, Daniel Mueller, Vivienne Armbruester, Pedro Mestres, and Klaus Roemer
Mol Cancer. 2008; 7: 54. Published online 2008 June 12. doi: 10.1186/1476-4598-7-54.
PMCID: PMC2440547
Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells
Annick Mühlethaler-Mottet, Roland Meier, Marjorie Flahaut, Katia Balmas Bourloud, Katya Nardou, Jean-Marc Joseph, and Nicole Gross
Mol Cancer. 2008; 7: 55. Published online 2008 June 12. doi: 10.1186/1476-4598-7-55.
PMCID: PMC2442609
Molecular profiling of angiogenesis in hypericin mediated photodynamic therapy
Ramaswamy Bhuvaneswari, Yik Y Gan, Sasidharan S Lucky, William WL Chin, Seyed M Ali, Khee C Soo, and Malini Olivo
Mol Cancer. 2008; 7: 56. Published online 2008 June 13. doi: 10.1186/1476-4598-7-56.
PMCID: PMC2440549
Identification of metabolites with anticancer properties by computational metabolomics
Adrian K Arakaki, Roman Mezencev, Nathan J Bowen, Ying Huang, John F McDonald, and Jeffrey Skolnick
Mol Cancer. 2008; 7: 57. Published online 2008 June 17. doi: 10.1186/1476-4598-7-57.
PMCID: PMC2453147
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha
Luigi Scotto, Gopeshwar Narayan, Subhadra V Nandula, Shivakumar Subramaniyam, Andreas M Kaufmann, Jason D Wright, Bhavana Pothuri, Mahesh Mansukhani, Achim Schneider, Hugo Arias-Pulido, and Vundavalli V Murty
Mol Cancer. 2008; 7: 58. Published online 2008 June 17. doi: 10.1186/1476-4598-7-58.
PMCID: PMC2440550
Smac/DIABLO enhances the therapeutic potential of chemotherapeutic drugs and irradiation, and sensitizes TRAIL-resistant breast cancer cells
Tamer E Fandy, Sharmila Shankar, and Rakesh K Srivastava
Mol Cancer. 2008; 7: 60. Published online 2008 June 30. doi: 10.1186/1476-4598-7-60.
PMCID: PMC2474652
Soluble histone H2AX is induced by DNA replication stress and sensitizes cells to undergo apoptosis
Ying Liu, Joshua A Parry, Anna Chin, Stefan Duensing, and Anette Duensing
Mol Cancer. 2008; 7: 61. Published online 2008 July 10. doi: 10.1186/1476-4598-7-61.
PMCID: PMC2481267
Identification of a panel of sensitive and specific DNA methylation markers for squamous cell lung cancer
Paul P Anglim, Janice S Galler, Michael N Koss, Jeffrey A Hagen, Sally Turla, Mihaela Campan, Daniel J Weisenberger, Peter W Laird, Kimberly D Siegmund, and Ite A Laird-Offringa
Mol Cancer. 2008; 7: 62. Published online 2008 July 10. doi: 10.1186/1476-4598-7-62.
PMCID: PMC2483990
The parafibromin tumor suppressor protein interacts with actin-binding proteins actinin-2 and actinin-3
Sunita K Agarwal, William F Simonds, and Stephen J Marx
Mol Cancer. 2008; 7: 65. Published online 2008 August 7. doi: 10.1186/1476-4598-7-65.
PMCID: PMC2519076
Gene expression time-series analysis of Camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines
Elena Morandi, Cinzia Severini, Daniele Quercioli, Giovanni D'Ario, Stefania Perdichizzi, Miriam Capri, Giovanna Farruggia, Maria Grazia Mascolo, Wolfango Horn, Monica Vaccari, Roberto Serra, Annamaria Colacci, and Paola Silingardi
Mol Cancer. 2008; 7: 66. Published online 2008 August 11. doi: 10.1186/1476-4598-7-66.
PMCID: PMC2556695
Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression
Frida Hansson, Jacek Toporski, Robert Månsson, Bertil Johansson, Ulrika Norén-Nyström, Sten Eirik W Jacobsen, Thomas Wiebe, Marcus Larsson, Mikael Sigvardsson, and Anders Castor
Mol Cancer. 2008; 7: 67. Published online 2008 August 11. doi: 10.1186/1476-4598-7-67.
PMCID: PMC2525657
Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study
Hassan Brim, Pooneh Mokarram, Fakhraddin Naghibalhossaini, Mehdi Saberi-Firoozi, Mansour Al-Mandhari, Kamla Al-Mawaly, Rayhaneh Al-Mjeni, Abeer Al-Sayegh, Sandy Raeburn, Edward Lee, Francis Giardiello, Duane T Smoot, Alexander Vilkin, C Richard Boland, Ajay Goel, Mitra Hafezi, Mehdi Nouraie, and Hassan Ashktorab
Mol Cancer. 2008; 7: 68. Published online 2008 August 21. doi: 10.1186/1476-4598-7-68.
PMCID: PMC2551625
Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK
Klaus Dittmann, Claus Mayer, Rainer Kehlbach, and H Peter Rodemann
Mol Cancer. 2008; 7: 69. Published online 2008 September 12. doi: 10.1186/1476-4598-7-69.
PMCID: PMC2546440
Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells
Marielle Dejligbjerg, Morten Grauslund, Thomas Litman, Laura Collins, Xiaozhong Qian, Michael Jeffers, Henri Lichenstein, Peter Buhl Jensen, and Maxwell Sehested
Mol Cancer. 2008; 7: 70. Published online 2008 September 12. doi: 10.1186/1476-4598-7-70.
PMCID: PMC2553797
Eplin-alpha expression in human breast cancer, the impact on cellular migration and clinical outcome
Wen G Jiang, Tracey A Martin, Jonathan M Lewis-Russell, Anthony Douglas-Jones, Lin Ye, and Robert E Mansel
Mol Cancer. 2008; 7: 71. Published online 2008 September 16. doi: 10.1186/1476-4598-7-71.
PMCID: PMC2553413
Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover
Carsten Denkert, Jan Budczies, Wilko Weichert, Gert Wohlgemuth, Martin Scholz, Tobias Kind, Silvia Niesporek, Aurelia Noske, Anna Buckendahl, Manfred Dietel, and Oliver Fiehn
Mol Cancer. 2008; 7: 72. Published online 2008 September 18. doi: 10.1186/1476-4598-7-72.
PMCID: PMC2569965
Rac1 GTPase and the Rac1 exchange factor Tiam1 associate with Wnt-responsive promoters to enhance beta-catenin/TCF-dependent transcription in colorectal cancer cells
Pinella Buongiorno, Vaijayanti V Pethe, George S Charames, Susmita Esufali, and Bharati Bapat
Mol Cancer. 2008; 7: 73. Published online 2008 September 30. doi: 10.1186/1476-4598-7-73.
PMCID: PMC2565678
Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma
Eric Smith, Neville J De Young, Sandra J Pavey, Nicholas K Hayward, Derek J Nancarrow, David C Whiteman, B Mark Smithers, Andrew R Ruszkiewicz, Andrew D Clouston, David C Gotley, Peter G Devitt, Glyn G Jamieson, and Paul A Drew
Mol Cancer. 2008; 7: 75. Published online 2008 October 2. doi: 10.1186/1476-4598-7-75.
PMCID: PMC2567345
A conserved acidic patch in the Myb domain is required for activation of an endogenous target gene and for chromatin binding
Emily Ray Ko, Dennis Ko, Carolyn Chen, and Joseph S Lipsick
Mol Cancer. 2008; 7: 77. Published online 2008 October 7. doi: 10.1186/1476-4598-7-77.
PMCID: PMC2572630
Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival
Chun-Liang Chen, Ling Cen, Jennifer Kohout, Brian Hutzen, Christina Chan, Fu-Chuan Hsieh, Abbey Loy, Victor Huang, Gong Cheng, and Jiayuh Lin
Mol Cancer. 2008; 7: 78. Published online 2008 October 21. doi: 10.1186/1476-4598-7-78.
PMCID: PMC2577686
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes
Teresa WM Fan, Magda Kucia, Kacper Jankowski, Richard M Higashi, Janina Ratajczak, Marius Z Ratajczak, and Andrew N Lane
Mol Cancer. 2008; 7: 79. Published online 2008 October 21. doi: 10.1186/1476-4598-7-79.
PMCID: PMC2577687
Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancer
Jürgen Veeck, Erik Noetzel, Nuran Bektas, Edgar Jost, Arndt Hartmann, Ruth Knüchel, and Edgar Dahl
Mol Cancer. 2008; 7: 83. Published online 2008 November 6. doi: 10.1186/1476-4598-7-83.
PMCID: PMC2613402
ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells
Jan S Moreb, Henry V Baker, Lung-Ji Chang, Maria Amaya, M Cecilia Lopez, Blanca Ostmark, and Wayne Chou
Mol Cancer. 2008; 7: 87. Published online 2008 November 24. doi: 10.1186/1476-4598-7-87.
PMCID: PMC2605459
Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling
Sinéad T Aherne, Paul C Smyth, Richard J Flavin, Susan M Russell, Karen M Denning, Jing Huan Li, Simone M Guenther, John J O'Leary, and Orla M Sheils
Mol Cancer. 2008; 7: 89. Published online 2008 December 4. doi: 10.1186/1476-4598-7-89.
PMCID: PMC2612696
Down-regulation of PPARgamma1 suppresses cell growth and induces apoptosis in MCF-7 breast cancer cells
Yekaterina Y Zaytseva, Xin Wang, R Chase Southard, Natalie K Wallis, and Michael W Kilgore
Mol Cancer. 2008; 7: 90. Published online 2008 December 5. doi: 10.1186/1476-4598-7-90.
PMCID: PMC2614423
Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context
Massimiliano Monticone, Emanuela Biollo, Massimo Maffei, Alessandra Donadini, Francesco Romeo, Clelia Tiziana Storlazzi, Walter Giaretti, and Patrizio Castagnola
Mol Cancer. 2008; 7: 92. Published online 2008 December 16. doi: 10.1186/1476-4598-7-92.
PMCID: PMC2615043
Correction
Involvement of GTA protein NC2beta in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation
Cinzia Di Pietro, Marco Ragusa, Davide Barbagallo, Laura R Duro, Maria R Guglielmino, Alessandra Majorana, Veronica Giunta, Antonella Rapisarda, Elisa Tricarichi, Marco Miceli, Rosario Angelica, Agata Grillo, Barbara Banelli, Isabella Defferari, Stefano Forte, Alessandro Laganà, Camillo Bosco, Rosalba Giugno, Alfredo Pulvirenti, Alfredo Ferro, Karl H Grzeschik, Andrea Di Cataldo, Gian P Tonini, Massimo Romani, and Michele Purrello
Mol Cancer. 2008; 7: 59. Published online 2008 June 30. doi: 10.1186/1476-4598-7-59.
PMCID: PMC2474651
Corrects: Cinzia Di Pietro, et al. Involvement of GTA protein NC2β in Neuroblastoma pathogenesis suggests that it physiologically participates in the regulation of cell proliferation. Mol Cancer. 2008; 7: 52.
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