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Fenoterol Analogues for Treating Congestive Heart Failure

Background:
The Laboratory of Clinical Investigation of the National Institute of Aging is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize fenoterol analogues and their use in treating congestive heart failure. Approximately 5 million individuals are diagnosed with congestive heart failure in the United States and an estimated 3.5 million hospitalizations are attributed to heart failure each year.

Technology:
This technology is directed to the discovery of (R,R)- and (R,S,)-fenoterol analogues which are highly effective at binding 2-adrenergic receptors. The patent application includes methods of using such compounds and compositions for the treatment of cardiac disorders such as congestive heart failure and pulmonary disorders such as asthma or chronic obstructive pulmonary disease.

IP Status:
U.S. Provisional Application filed August, 2006.

Contact Information:
John D. Hewes, Ph.D., NCI Technology Transfer Center
Phone: 301-435-3121
E-mail: Hewesj@mail.nih.gov

Reference:  #454 ND

Updated 10/25/2007


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Page Last Updated: 12-17-2008