Fenoterol Analogues for Treating Congestive Heart Failure
Background:
The Laboratory of Clinical
Investigation of the National Institute of Aging is seeking
statements of capability or interest from parties interested in
collaborative research to further develop, evaluate, or
commercialize fenoterol analogues and their use in treating
congestive heart failure. Approximately 5 million individuals are
diagnosed with congestive heart failure in the United States and an
estimated 3.5 million hospitalizations are attributed to heart
failure each year.
Technology:
This technology is directed to
the discovery of (R,R)- and (R,S,)-fenoterol analogues which are
highly effective at binding 2-adrenergic receptors. The patent
application includes methods of using such compounds and
compositions for the treatment of cardiac disorders such as
congestive heart failure and pulmonary disorders such as asthma or
chronic obstructive pulmonary disease.
IP Status:
U.S.
Provisional Application filed August, 2006.
Contact
Information:
John D. Hewes, Ph.D., NCI
Technology Transfer Center
Phone: 301-435-3121
E-mail: Hewesj@mail.nih.gov
Reference: #454 ND
Updated 10/25/2007