The Remarkable Biology of Short RNAs

 


  Launch in standalone player
 
Air date: Wednesday, June 16, 2004, 3:00:00 PM
Category: Wednesday Afternoon Lectures
Description: The discovery of RNA Interference, specifically the importance of double-strand RNA as the key signal for gene silencing, stimulated the emergence of a new field of Biology concerning the functions of short RNAs. Partially double strand short RNAs, 21-23 nucleotides in length, target mRNA for cleavage and their use has revolutionized approaches to determine genotype/phenotype relationships in mammalian cells. Short RNAs, microRNAs, are also encoded by endogenous genes and recent studies have identified some of their regulatory targets.

For more information, visit Phillip Sharp at
MIT and 1993 Nobel Laureate in Medicine

NIH Director's Wednesday Afternoon Lecture Series
Author: Phillip A. Sharp, Ph.D., MIT and 1993 Nobel Laureate in Medicine
Runtime: 90 minutes
Rights: This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
Download: Download Video
How to download a Videocast
CIT File ID: 13969
CIT Live ID: 2631
Permanent link: http://videocast.nih.gov/launch.asp?13969