The Remarkable Biology of Short RNAs |
|
---|---|
|
|
Launch in standalone player | |
Air date: | Wednesday, June 16, 2004, 3:00:00 PM |
Category: | Wednesday Afternoon Lectures |
Description: | The discovery of RNA Interference, specifically the importance of double-strand RNA as the key signal for gene silencing, stimulated the emergence of a new field of Biology concerning the functions of short RNAs. Partially double strand short RNAs, 21-23 nucleotides in length, target mRNA for cleavage and their use has revolutionized approaches to determine genotype/phenotype relationships in mammalian cells. Short RNAs, microRNAs, are also encoded by endogenous genes and recent studies have identified some of their regulatory targets.
For more information, visit Phillip Sharp at MIT and 1993 Nobel Laureate in Medicine NIH Director's Wednesday Afternoon Lecture Series |
Author: | Phillip A. Sharp, Ph.D., MIT and 1993 Nobel Laureate in Medicine |
Runtime: | 90 minutes |
Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
Download: | Download
Video How to download a Videocast |
CIT File ID: | 13969 |
CIT Live ID: | 2631 |
Permanent link: | http://videocast.nih.gov/launch.asp?13969 |