Imaging the Structure and Function of the Cortical Microcircuit |
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| Launch in standalone player | |
| Air date: | Wednesday, May 05, 2004, 3:00:00 PM |
| Category: | Wednesday Afternoon Lectures |
| Description: | Spontaneous cortical activity is prevalent in vivo and in vitro and its dynamics could reveal basic features about the structure and function (and help illuminate the logic) of the cortical microcircuitry. We have investigated these dynamics with single cell resolution, using calcium imaging to reveal action-potential associated calcium transients. Using two-photon or spinning disk confocal microscopy, we performed fast imaging of calcium events simultaneously from more than 3000 neurons in a slice of P14-30 mouse prefrontal and visual cortex in order to reconstruct the spatiotemporal dynamics of spontaneous activity.
For more information, visit Rafael Yuste The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. |
| Author: | Rafael Yuste, M.D., Ph.D. Columbia University |
| Runtime: | 01:09:20 |
| Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 12005 |
| CIT Live ID: | 2626 |
| Permanent link: | http://videocast.nih.gov/launch.asp?12005 |