Morphogenesis and Oncogenesis in 3D Epithelial Cultures

 


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Air date: Wednesday, September 15, 2004, 3:00:00 PM
Category: Wednesday Afternoon Lectures
Description: The proliferation, survival and branching of mammary epithelial cells is highly influenced by interactions of the epithelial cells with other cells, with their surrounding extracellular matrix, and with hormones and other regulatory factors in their microenvironment. Oncogenes, tumor suppressor genes, and factors in the microenvironment allow cells to escape regulatory controls imposed on cells in their natural tissue environment, thus leading to progressive changes in the organization of cells, their proliferative capacity, their sensitivity to stress-induced death and their ability to escape from their natural environment.

The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide.

For more information, visit
http://cellbio.med.harvard.edu/faculty/brugge
Author: Joan S.Brugge, Ph.D., Harvard Medical School
Runtime: 75 minutes
Rights: This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely.
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CIT File ID: 12147
CIT Live ID: 3424
Permanent link: http://videocast.nih.gov/launch.asp?12147